FTL and SPINK7

Number of citations of the paper that reports this interaction (PMID 12646258)
4

Data Source:
BioGRID (two hybrid)

		FTL	SPINK7
Gene Name		ferritin, light polypeptide	serine peptidase inhibitor, Kazal type 7 (putative)
Image
Gene Ontology Annotations	Cellular Component	Cytosol Intracellular Ferritin Complex Membrane Extracellular Vesicular Exosome	Extracellular Region
	Molecular Function	Iron Ion Binding Protein Binding Ferric Iron Binding Identical Protein Binding	Serine-type Endopeptidase Inhibitor Activity Protein Binding
	Biological Process	Iron Ion Transport Cellular Iron Ion Homeostasis Post-Golgi Vesicle-mediated Transport Receptor-mediated Endocytosis Iron Ion Homeostasis Transmembrane Transport Membrane Organization	Negative Regulation Of Endopeptidase Activity
Pathways		Iron uptake and transport Golgi Associated Vesicle Biogenesis Scavenging by Class A Receptors trans-Golgi Network Vesicle Budding Clathrin derived vesicle budding
Drugs		Iron Dextran Protoporphyrin Ix
Diseases
GWAS
Protein-Protein Interactions		24 interactors: CLEC4G FTH1 GADD45A GRB2 HTT IGDCC3 KNG1 KPNA3 MAP3K12 MPHOSPH6 MPP6 MYOC MYOG PIK3CA PPP1CC PTN RAP2A SDCBP SMAD9 SPINK7 TAF10 USHBP1 VKORC1 ZDHHC17	8 interactors: EPB42 FTL HBA1 MRPS12 MT1G MT1H MT2A RABL6
Entrez ID		2512	84651
HPRD ID		00616	16850
Ensembl ID		ENSG00000087086	ENSG00000145879
Uniprot IDs		P02792	P58062
PDB IDs		2FFX 2FG4 2FG8 3HX2 3HX5 3HX7 3KXU	2LEO
Enriched GO Terms of Interacting Partners?		Enzyme Linked Receptor Protein Signaling Pathway Regulation Of MAPK Cascade Regulation Of Phosphorus Metabolic Process Response To Stimulus Positive Regulation Of Intracellular Signal Transduction Muscle System Process Positive Regulation Of Signal Transduction Regulation Of Intracellular Signal Transduction Regulation Of Phosphorylation Maturation Of 5.8S RRNA Cellular Response To Growth Factor Stimulus Signal Transduction Response To Growth Factor Response To Abiotic Stimulus Signaling Regulation Of Metabolic Process Cellular Response To Stimulus Regulation Of Signal Transduction Cell Communication ERBB Signaling Pathway Regulation Of JNK Cascade Blood Coagulation Hemostasis Regulation Of Stress-activated MAPK Cascade Response To Radiation Platelet Activation Membrane Organization Positive Regulation Of Phosphorylation Regulation Of Signaling Intracellular Signal Transduction Neural Plate Formation Skeletal Muscle Hypertrophy Positive Regulation Of Muscle Atrophy ERBB2-ERBB3 Signaling Pathway Ras Protein Signal Transduction Cellular Response To Organic Substance Cell Surface Receptor Signaling Pathway Cellular Component Assembly Bone Development Positive Regulation Of Cellular Metabolic Process Cellular Response To Ionizing Radiation Regulation Of Body Fluid Levels Hypomethylation Of CpG Island Response To Muscle Activity Involved In Regulation Of Muscle Adaptation Intracellular Sequestering Of Iron Ion Serotonin Uptake ERBB2 Signaling Pathway Lactate Biosynthetic Process From Pyruvate Viral Penetration Into Host Nucleus Positive Regulation Of Metabolic Process	Cellular Response To Zinc Ion Response To Zinc Ion Cellular Response To Metal Ion Response To Inorganic Substance Cellular Response To Inorganic Substance Transition Metal Ion Homeostasis Cellular Response To Cadmium Ion Negative Regulation Of Growth Response To Metal Ion Response To Cadmium Ion Metal Ion Homeostasis Iron Ion Homeostasis Ion Homeostasis Regulation Of Growth Cellular Response To Erythropoietin Cellular Response To Interleukin-3 Cellular Response To Copper Ion Chemical Homeostasis Monocyte Activation Myeloid Cell Differentiation Erythrocyte Maturation Hemoglobin Metabolic Process Receptor-mediated Endocytosis Cellular Copper Ion Homeostasis Monocyte Differentiation Hydrogen Peroxide Catabolic Process Cellular Metal Ion Homeostasis Copper Ion Homeostasis Response To Copper Ion Oxygen Transport Homeostatic Process Cellular Cation Homeostasis Cellular Ion Homeostasis Bicarbonate Transport Hydrogen Peroxide Metabolic Process Cellular Chemical Homeostasis Cellular Response To Vascular Endothelial Growth Factor Stimulus Erythrocyte Development Peptide Cross-linking Spleen Development
Tagcloud ?		apoc2 atp1a3 bckdha cgb cgm2 cyp2a d19s112 d19s116 d19s117 d19s118 d19s119 d19s19 d19s2 d19s37 d19s50 d19s51 d19s54 d19s55 d19s6 d19s62 d19s63 d19s7 d19s8 d19s9 manb pepd prkcg psg1 pw39 tnnt1
Tagcloud (Difference) ?		apoc2 atp1a3 bckdha cgb cgm2 cyp2a d19s112 d19s116 d19s117 d19s118 d19s119 d19s19 d19s2 d19s37 d19s50 d19s51 d19s54 d19s55 d19s6 d19s62 d19s63 d19s7 d19s8 d19s9 manb pepd prkcg psg1 pw39 tnnt1
Tagcloud (Intersection) ?