FTL and SDCBP

Number of citations of the paper that reports this interaction (PMID 25416956)
0

Data Source:
BioGRID (two hybrid)

		FTL	SDCBP
Gene Name		ferritin, light polypeptide	syndecan binding protein (syntenin)
Image
Gene Ontology Annotations	Cellular Component	Cytosol Intracellular Ferritin Complex Membrane Extracellular Vesicular Exosome	Extracellular Space Nucleus Cytoplasm Endoplasmic Reticulum Membrane Cytosol Cytoskeleton Plasma Membrane Interleukin-5 Receptor Complex Adherens Junction Focal Adhesion Membrane Vesicle Melanosome Extracellular Vesicular Exosome Blood Microparticle
	Molecular Function	Iron Ion Binding Protein Binding Ferric Iron Binding Identical Protein Binding	Glycoprotein Binding Frizzled Binding Interleukin-5 Receptor Binding Protein Binding Protein C-terminus Binding Cytoskeletal Adaptor Activity Growth Factor Binding Neurexin Family Protein Binding Identical Protein Binding Protein Homodimerization Activity Syndecan Binding Ephrin Receptor Binding Protein Heterodimerization Activity Protein N-terminus Binding Cell Adhesion Molecule Binding
	Biological Process	Iron Ion Transport Cellular Iron Ion Homeostasis Post-Golgi Vesicle-mediated Transport Receptor-mediated Endocytosis Iron Ion Homeostasis Transmembrane Transport Membrane Organization	Protein Targeting To Membrane Substrate-dependent Cell Migration, Cell Extension Ras Protein Signal Transduction Synaptic Transmission Axon Guidance Actin Cytoskeleton Organization Intracellular Signal Transduction Positive Regulation Of Phosphorylation Positive Regulation Of JNK Cascade Ephrin Receptor Signaling Pathway Positive Regulation Of Exosomal Secretion Positive Regulation Of Extracellular Vesicular Exosome Assembly
Pathways		Iron uptake and transport Golgi Associated Vesicle Biogenesis Scavenging by Class A Receptors trans-Golgi Network Vesicle Budding Clathrin derived vesicle budding	Ephrin signaling Axon guidance Neurofascin interactions EPH-Ephrin signaling L1CAM interactions
Drugs		Iron Dextran Protoporphyrin Ix
Diseases
GWAS
Protein-Protein Interactions		24 interactors: CLEC4G FTH1 GADD45A GRB2 HTT IGDCC3 KNG1 KPNA3 MAP3K12 MPHOSPH6 MPP6 MYOC MYOG PIK3CA PPP1CC PTN RAP2A SDCBP SMAD9 SPINK7 TAF10 USHBP1 VKORC1 ZDHHC17	167 interactors: ABI2 AES ANKRD40 ANP32B APIP BCL2L15 C11orf57 C11orf68 C1orf109 CADM1 CADPS CALCOCO2 CBR3 CCDC102B CCDC36 CCDC53 CD6 CD63 CDA CDC34 CDCP1 CDIPT CEP55 CGGBP1 CLK2 CLK3 CMTM5 COX4I1 CRYAA CT45A3 CT45A5 CUTC DAK DCTD DCTPP1 DMC1 DTNBP1 EAF1 EDARADD EFNB1 EFNB2 EIF1AD EIF5A2 ELAVL1 ENOX1 EPHB2 ERICH2 FAM118A FAM118B FAM9B FLAD1 FOXP2 FTH1 FTL GNMT GPATCH11 GPR37 GRIA1 GRIA2 GRIA3 GRIA4 GRIK1 GRIK2 GRIK3 GRM3 HIVEP1 HMGB3 HNRNPC HOMEZ HOXA1 HPRT1 HSBP1 IKZF1 IL5RA INO80E KCNH1 KCTD1 KCTD6 KCTD9 KHDRBS2 KLHL12 KLHL2 KRTAP10-3 KRTAP10-7 KRTAP5-9 LDOC1 LGALS2 LSM6 LZTFL1 MAD2L1 MAPRE3 MBD3 MED4 MID2 MRFAP1L1 MTUS2 NADK NAGK NECAB2 NF2 NFASC NOTCH2NL NT5C2 OSTF1 PDCD6IP PDE4DIP PHC2 PNMA1 PNMA2 PRPF38A PRPF40A PRR13 PSMC6 PSTPIP1 PTPRJ PTS PUF60 PYCRL RAB5A RBM39 REEP6 REL RIC8A RNF11 RNH1 ROPN1 RP9P RTN1 RUNDC3A SDC1 SDC2 SDC4 SDCBP2 SDCCAG3 SEPT3 SET SIAH1 SLC6A5 SMARCA2 SOX4 SREK1IP1 SRSF11 SRSF7 SSNA1 STX1A SULT1B1 TDO2 TEKT1 TFCP2 TGFA THG1L TIFA TMEM239 TNFAIP8 TRAF5 TRIM27 TRIM32 TRIM38 TRIM54 UBE2A ULK1 WASL WDR91 ZBTB14 ZBTB8A ZCCHC10 ZCCHC17
Entrez ID		2512	6386
HPRD ID		00616	03741
Ensembl ID		ENSG00000087086	ENSG00000137575
Uniprot IDs		P02792	B4DHN5 G5EA09 O00560
PDB IDs		2FFX 2FG4 2FG8 3HX2 3HX5 3HX7 3KXU	1N99 1NTE 1OBX 1OBY 1OBZ 1R6J 1V1T 1W9E 1W9O 1W9Q 1YBO
Enriched GO Terms of Interacting Partners?		Enzyme Linked Receptor Protein Signaling Pathway Regulation Of MAPK Cascade Regulation Of Phosphorus Metabolic Process Response To Stimulus Positive Regulation Of Intracellular Signal Transduction Muscle System Process Positive Regulation Of Signal Transduction Regulation Of Intracellular Signal Transduction Regulation Of Phosphorylation Maturation Of 5.8S RRNA Cellular Response To Growth Factor Stimulus Signal Transduction Response To Growth Factor Response To Abiotic Stimulus Signaling Regulation Of Metabolic Process Cellular Response To Stimulus Regulation Of Signal Transduction Cell Communication ERBB Signaling Pathway Regulation Of JNK Cascade Blood Coagulation Hemostasis Regulation Of Stress-activated MAPK Cascade Response To Radiation Platelet Activation Membrane Organization Positive Regulation Of Phosphorylation Regulation Of Signaling Intracellular Signal Transduction Neural Plate Formation Skeletal Muscle Hypertrophy Positive Regulation Of Muscle Atrophy ERBB2-ERBB3 Signaling Pathway Ras Protein Signal Transduction Cellular Response To Organic Substance Cell Surface Receptor Signaling Pathway Cellular Component Assembly Bone Development Positive Regulation Of Cellular Metabolic Process Cellular Response To Ionizing Radiation Regulation Of Body Fluid Levels Hypomethylation Of CpG Island Response To Muscle Activity Involved In Regulation Of Muscle Adaptation Intracellular Sequestering Of Iron Ion Serotonin Uptake ERBB2 Signaling Pathway Lactate Biosynthetic Process From Pyruvate Viral Penetration Into Host Nucleus Positive Regulation Of Metabolic Process	Glutamate Receptor Signaling Pathway Ionotropic Glutamate Receptor Signaling Pathway Synaptic Transmission, Glutamatergic Neuron-neuron Synaptic Transmission Positive Regulation Of Extracellular Vesicular Exosome Assembly Regulation Of Cellular Process Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Nitrogen Compound Metabolic Process Regulation Of Extracellular Vesicular Exosome Assembly Synaptic Transmission Nucleobase-containing Compound Metabolic Process Cellular Nitrogen Compound Metabolic Process Protein Homooligomerization Positive Regulation Of Exocytosis Protein Tetramerization Positive Regulation Of Exosomal Secretion Regulation Of Exosomal Secretion Cellular Metabolic Process Regulation Of Cellular Component Organization Protein Oligomerization Protein Homotetramerization Negative Regulation Of Synaptic Transmission, Glutamatergic Response To Stimulus Cell-cell Signaling Regulation Of Synaptic Transmission Cellular Process Protein Complex Assembly Positive Regulation Of Cellular Component Biogenesis Negative Regulation Of Viral Release From Host Cell Gene Expression Positive Regulation Of Secretion Protein Ubiquitination Negative Regulation Of Cellular Metabolic Process RNA Splicing Protein Modification By Small Protein Conjugation Positive Regulation Of Dopamine Metabolic Process Negative Regulation Of Biosynthetic Process Transcription, DNA-templated Ephrin Receptor Signaling Pathway Regulation Of Exocytosis Negative Regulation Of Viral Transcription Regulation Of Viral Release From Host Cell Nucleoside Metabolic Process Adenylate Cyclase-inhibiting G-protein Coupled Receptor Signaling Pathway Positive Regulation Of Organelle Assembly Negative Regulation Of Synaptic Transmission RNA Biosynthetic Process Regulation Of Synaptic Transmission, Glutamatergic Protein Polyubiquitination
Tagcloud ?		apoc2 atp1a3 bckdha cgb cgm2 cyp2a d19s112 d19s116 d19s117 d19s118 d19s119 d19s19 d19s2 d19s37 d19s50 d19s51 d19s54 d19s55 d19s6 d19s62 d19s63 d19s7 d19s8 d19s9 manb pepd prkcg psg1 pw39 tnnt1	conversely datasets fak healing hepatocyte hgf il2rgamma immunofluorescence indication lethality matrigel mda melanoma melanomas metastases metastasizes metastatic migrate opposite pseudo scid syndecan syndecans syntenin triggered unrelated uveal warrants wound
Tagcloud (Difference) ?		apoc2 atp1a3 bckdha cgb cgm2 cyp2a d19s112 d19s116 d19s117 d19s118 d19s119 d19s19 d19s2 d19s37 d19s50 d19s51 d19s54 d19s55 d19s6 d19s62 d19s63 d19s7 d19s8 d19s9 manb pepd prkcg psg1 pw39 tnnt1	conversely datasets fak healing hepatocyte hgf il2rgamma immunofluorescence indication lethality matrigel mda melanoma melanomas metastases metastasizes metastatic migrate opposite pseudo scid syndecan syndecans syntenin triggered unrelated uveal warrants wound
Tagcloud (Intersection) ?