KAT6B and ATN1

Number of citations of the paper that reports this interaction (PMID 16713569)
214

Data Source:
BioGRID (two hybrid)
HPRD (two hybrid)

		KAT6B	ATN1
Gene Name		K(lysine) acetyltransferase 6B	atrophin 1
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleosome Nucleus Nucleoplasm MOZ/MORF Histone Acetyltransferase Complex	Nucleus Nucleoplasm Cytoplasm Nuclear Matrix Cell Junction Perinuclear Region Of Cytoplasm
	Molecular Function	DNA Binding Histone Acetyltransferase Activity Protein Binding Transcription Factor Binding Zinc Ion Binding Acetyltransferase Activity	Transcription Corepressor Activity Protein Binding Protein Domain Specific Binding Toxin Receptor Binding
	Biological Process	Chromatin Organization Nucleosome Assembly Transcription, DNA-templated Regulation Of Transcription, DNA-templated Histone Acetylation Histone H3 Acetylation Negative Regulation Of Transcription, DNA-templated Positive Regulation Of Transcription, DNA-templated	Negative Regulation Of Transcription From RNA Polymerase II Promoter Transcription, DNA-templated Central Nervous System Development Toxin Metabolic Process Cell Migration Maintenance Of Cell Polarity Neuron Apoptotic Process
Pathways		Chromatin modifying enzymes Chromatin organization HATs acetylate histones
Drugs
Diseases
GWAS
Protein-Protein Interactions		4 interactors: ATN1 RUNX1 RUNX2 SUMO1	93 interactors: AES AGRN ALG13 ARF3 ATRX BAG6 BAIAP2 CACNB1 CASP1 CASP3 CBFA2T2 CENPJ CHRD CRACR2A CRIP2 CTNND2 DMPK DVL1 DVL2 ECM1 EFEMP1 EFEMP2 EWSR1 FBLN1 FBLN2 FBLN5 GAPDH GCC1 GIGYF1 GRN HINFP HSPG2 ITCH JAG2 KAT6A KAT6B KAT7 KRT31 KRTAP4-12 LENG8 LRP2 LTBP1 LTBP4 LYST MAGI1 MAGI2 MAP7D1 MBP MDFI MEGF11 MEGF6 MEGF8 NCK2 NELL1 NELL2 NOC2L NR2E1 PCSK5 PDCD6IP PFKL PLSCR1 PRRC2A PRRC2B PSMA3 PSME3 RAD54L2 RBFOX1 RBFOX2 RBM10 RBPMS RCHY1 RERE RHOXF2 RNF115 RNF31 RUNX1T1 SIAH1 SIAH2 SLIT1 SPAG5 SSPO STXBP4 SYVN1 TEP1 TLE1 TRIP6 USP54 VIM WDR5 WWP1 WWP2 ZMYND8 ZSWIM8
Entrez ID		23522	1822
HPRD ID		07065	06311
Ensembl ID		ENSG00000156650	ENSG00000111676
Uniprot IDs		B2RWN8 Q8WYB5	P54259 Q86V38
PDB IDs
Enriched GO Terms of Interacting Partners?		Positive Regulation Of Progesterone Secretion Negative Regulation Of Transcription, DNA-templated Negative Regulation Of Nucleic Acid-templated Transcription Negative Regulation Of RNA Biosynthetic Process Regulation Of Progesterone Secretion PML Body Organization Regulation Of Hair Follicle Cell Proliferation Negative Regulation Of Gene Expression Negative Regulation Of Biosynthetic Process Protein Localization To Nuclear Pore Protein Localization To Nuclear Envelope Regulation Of Transcription, DNA-templated Regulation Of Nucleic Acid-templated Transcription Regulation Of RNA Biosynthetic Process Negative Regulation Of Granulocyte Differentiation Regulation Of RNA Metabolic Process Myeloid Progenitor Cell Differentiation Positive Regulation Of Granulocyte Differentiation Nucleobase-containing Compound Metabolic Process Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Regulation Of Transcription From RNA Polymerase II Promoter Regulation Of Gene Expression Cellular Response To Organic Substance Anatomical Structure Development Osteoblast Fate Commitment Peripheral Nervous System Neuron Development Regulation Of Female Gonad Development Maintenance Of Cell Polarity Regulation Of Nitrogen Compound Metabolic Process Cellular Nitrogen Compound Metabolic Process Toxin Metabolic Process Embryonic Organ Development Hematopoietic Stem Cell Proliferation Negative Regulation Of Cellular Metabolic Process Regulation Of Odontogenesis Of Dentin-containing Tooth Immune System Process Developmental Process Nitrogen Compound Metabolic Process Skeletal System Development Transcription, DNA-templated Cellular Response To Growth Factor Stimulus Regulation Of Interferon-gamma-mediated Signaling Pathway Behavioral Response To Pain Response To Growth Factor Regulation Of Response To Interferon-gamma RNA Biosynthetic Process Definitive Hemopoiesis Hemopoiesis Protein Sumoylation	Regulation Of Cellular Process Regulation Of Metabolic Process Negative Regulation Of Cellular Metabolic Process Multicellular Organismal Development Regulation Of Nitrogen Compound Metabolic Process Developmental Process Regulation Of Gene Expression Signaling Regulation Of Signaling Signal Transduction Nervous System Development Anatomical Structure Development Cell Communication Negative Regulation Of Signaling Negative Regulation Of Signal Transduction Regulation Of RNA Metabolic Process Cellular Response To Stimulus Proteolysis Involved In Cellular Protein Catabolic Process Extracellular Matrix Organization Extracellular Structure Organization Cellular Protein Catabolic Process Regulation Of Nucleic Acid-templated Transcription Regulation Of Proteolysis Regulation Of RNA Biosynthetic Process System Development Response To Stimulus Cell Death Death Ubiquitin-dependent Protein Catabolic Process Anatomical Structure Morphogenesis Modification-dependent Protein Catabolic Process Protein Catabolic Process Apoptotic Process Negative Regulation Of Wnt Signaling Pathway Programmed Cell Death Regulation Of Transcription, DNA-templated Regulation Of Signal Transduction Negative Regulation Of Cellular Protein Metabolic Process Regulation Of Cellular Protein Metabolic Process Cellular Macromolecule Catabolic Process Regulation Of Protein Metabolic Process Negative Regulation Of Nucleic Acid-templated Transcription Negative Regulation Of RNA Biosynthetic Process Protein Ubiquitination Involved In Ubiquitin-dependent Protein Catabolic Process Negative Regulation Of Protein Metabolic Process Regulation Of Cellular Component Organization Enzyme Linked Receptor Protein Signaling Pathway Negative Regulation Of Biosynthetic Process Protein Ubiquitination Axon Development
Tagcloud ?		acetal applying arises brca1 brca2 carrier clustering coding damaging decade detects dispositions entire exome exons familial families focusing germline identifying nonsynonymous obligate predisposition sanger sequenced spite transferase unaffected variants	atrophin1 atrophy chip cortical degenerative demethylase dentatorubral depletion h3k4 hint inducing knockout lbal lsd1 lysine maintenance methylation npc pallidoluysian phenocopied poorly precise premature progenitor repression rescued seq surprisingly tranylcypromine
Tagcloud (Difference) ?		acetal applying arises brca1 brca2 carrier clustering coding damaging decade detects dispositions entire exome exons familial families focusing germline identifying nonsynonymous obligate predisposition sanger sequenced spite transferase unaffected variants	atrophin1 atrophy chip cortical degenerative demethylase dentatorubral depletion h3k4 hint inducing knockout lbal lsd1 lysine maintenance methylation npc pallidoluysian phenocopied poorly precise premature progenitor repression rescued seq surprisingly tranylcypromine
Tagcloud (Intersection) ?