SYNM and DTNA

Number of citations of the paper that reports this interaction (PMID 11353857)
18

Data Source:
HPRD (in vitro, two hybrid)

		SYNM	DTNA
Gene Name		synemin, intermediate filament protein	dystrobrevin, alpha
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Intermediate Filament Adherens Junction Membrane Costamere Neurofilament Cytoskeleton	Cytoplasm Cell Junction Axon Extrinsic Component Of Cytoplasmic Side Of Plasma Membrane Sarcolemma Protein Complex Synapse
	Molecular Function	Structural Constituent Of Cytoskeleton Protein Binding Structural Constituent Of Muscle Vinculin Binding Intermediate Filament Binding	Protein Binding Zinc Ion Binding PDZ Domain Binding
	Biological Process	Intermediate Filament Cytoskeleton Organization	Striated Muscle Contraction Signal Transduction Synaptic Transmission Neuromuscular Synaptic Transmission
Pathways
Drugs
Diseases
GWAS
Protein-Protein Interactions		2 interactors: DES DTNA	14 interactors: ACTA1 DMD DRP2 DTNBP1 GFI1B KCNJ12 SNTA1 SNTB1 SNTB2 SNTG1 SNTG2 SYNC SYNM UTRN
Entrez ID		23336	1837
HPRD ID		07305	03141
Ensembl ID		ENSG00000182253	ENSG00000134769
Uniprot IDs		O15061	A8K541 B7Z3X3 M0QYX6 Q9Y4J8
PDB IDs			2E5R
Enriched GO Terms of Interacting Partners?		Muscle Contraction Muscle System Process Neuromuscular Synaptic Transmission Muscle Filament Sliding Actin-myosin Filament Sliding Actin-mediated Cell Contraction Actin Filament-based Movement Striated Muscle Contraction Regulation Of Heart Contraction	Muscle Contraction Muscle System Process Negative Regulation Of Peptidyl-cysteine S-nitrosylation Regulation Of Sodium Ion Transmembrane Transport Regulation Of Sodium Ion Transport Regulation Of Ion Transport Regulation Of Ion Transmembrane Transport Regulation Of Heart Contraction Regulation Of Sodium Ion Transmembrane Transporter Activity Myotube Cell Development Actin-myosin Filament Sliding Muscle Filament Sliding Cardiac Muscle Cell Action Potential Intermediate Filament-based Process Actin-mediated Cell Contraction Muscle Fiber Development Positive Regulation Of Cell-matrix Adhesion Muscle Organ Development Myotube Differentiation Actin Filament-based Movement Regulation Of Vasoconstriction By Circulating Norepinephrine Regulation Of Heart Rate Regulation Of Cardiac Muscle Contraction Action Potential Regulation Of Striated Muscle Contraction Skeletal Muscle Fiber Adaptation Establishment Of Glial Blood-brain Barrier Regulation Of Cell-matrix Adhesion Positive Regulation Of Cell-substrate Adhesion Muscle Structure Development Skeletal Muscle Tissue Development Regulation Of Skeletal Muscle Contraction By Regulation Of Release Of Sequestered Calcium Ion Establishment Of Blood-nerve Barrier Regulation Of Ion Transmembrane Transporter Activity Regulation Of Transmembrane Transporter Activity Skeletal Muscle Organ Development System Development Regulation Of Muscle Contraction Striated Muscle Cell Development Synaptic Transmission Regulation Of Dopamine Receptor Signaling Pathway Skeletal Muscle Thin Filament Assembly Olfactory Nerve Development Muscle Cell Development Regulation Of Skeletal Muscle Contraction Actin Filament-based Process Skeletal Myofibril Assembly Neurotransmitter Receptor Metabolic Process Regulation Of Cell-substrate Adhesion Platelet Dense Granule Organization
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