JMJD6 and NHP2

Number of citations of the paper that reports this interaction (PMID 23455924)
3

Data Source:
BioGRID (two hybrid)

		JMJD6	NHP2
Gene Name		jumonji domain containing 6	NHP2 ribonucleoprotein
Image			No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleus Nucleoplasm Nucleolus Plasma Membrane	Nucleoplasm Nucleolus Small Nucleolar Ribonucleoprotein Complex Cytoplasm Cajal Body
	Molecular Function	RNA Binding Single-stranded RNA Binding Receptor Activity Iron Ion Binding Protein Binding Histone Demethylase Activity (H3-R2 Specific) Histone Demethylase Activity (H4-R3 Specific) Identical Protein Binding Peptidyl-lysine 5-dioxygenase Activity	SnoRNA Binding Poly(A) RNA Binding
	Biological Process	Kidney Development Sprouting Angiogenesis Transcription, DNA-templated Regulation Of Transcription, DNA-templated MRNA Processing Cell Surface Receptor Signaling Pathway Heart Development RNA Splicing Peptidyl-lysine Hydroxylation To 5-hydroxy-L-lysine Lung Development T Cell Differentiation In Thymus Macrophage Activation Recognition Of Apoptotic Cell Regulation Of MRNA Splicing, Via Spliceosome Erythrocyte Development Oxidation-reduction Process Retina Development In Camera-type Eye Histone H3-R2 Demethylation Histone H4-R3 Demethylation	RRNA Pseudouridine Synthesis
Pathways			Telomere Maintenance Chromosome Maintenance Extension of Telomeres Telomere Extension By Telomerase
Drugs
Diseases
GWAS		Retinal arteriolar caliber ( 23776548)
Protein-Protein Interactions		28 interactors: AEBP2 ANKEF1 BRD4 C17orf97 CCNL1 CENPL DIP2A FAM9A FGD5 FRMD6 GNA14 HIST1H2BJ HMGXB4 LARP7 NAA50 NFIX NHP2 PRPF38A PSMC1 RSPO2 RSRC1 SLFN12 SLU7 STAC3 TAF1A U2AF1 ZCCHC17 ZNF451	8 interactors: IKBKG JMJD6 MYL2 NEDD4 NEDD4L NOP10 PRNP UBC
Entrez ID		23210	55651
HPRD ID		05371	07570
Ensembl ID		ENSG00000070495	ENSG00000145912
Uniprot IDs		Q6NYC1	J3QSY4 Q9NX24
PDB IDs		3K2O 3LD8 3LDB
Enriched GO Terms of Interacting Partners?		Chromatin Organization RNA Processing RNA Metabolic Process Gene Expression Chromosome Organization Alternative MRNA Splicing, Via Spliceosome Nucleosome Assembly Chromatin Modification Cellular Nitrogen Compound Metabolic Process Chromatin Assembly RNA Splicing Nucleosome Organization Chromatin Assembly Or Disassembly G1/S Transition Of Mitotic Cell Cycle Nucleobase-containing Compound Metabolic Process Protein-DNA Complex Assembly Mitotic Cell Cycle MRNA Processing Chromatin Remodeling DNA Packaging Nitrogen Compound Metabolic Process Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Mitotic Sister Chromatid Cohesion, Centromeric RRNA Pseudouridine Synthesis Histone H4 Acetylation MRNA Splicing, Via Spliceosome RNA Splicing, Via Transesterification Reactions MRNA Metabolic Process Regulation Of Phosphorylation Of RNA Polymerase II C-terminal Domain Mitotic Cell Cycle Phase Transition Cell Cycle Phase Transition DNA-templated Transcription, Termination Negative Regulation Of Gene Expression, Epigenetic DNA Conformation Change Regulation Of Wnt Signaling Pathway Cellular Macromolecular Complex Assembly Negative Regulation Of DNA Damage Checkpoint Apical Constriction Lung Growth Histone H3-K14 Acetylation Mitotic Cell Cycle Process MRNA 3'-splice Site Recognition Transcription, DNA-templated Histone Acetylation Trachea Cartilage Morphogenesis Internal Peptidyl-lysine Acetylation Positive Regulation Of Canonical Wnt Signaling Pathway Peptidyl-lysine Acetylation Internal Protein Amino Acid Acetylation	Regulation Of Potassium Ion Transmembrane Transport Regulation Of Potassium Ion Transport Negative Regulation Of Cellular Response To Growth Factor Stimulus Negative Regulation Of Sodium Ion Transport Negative Regulation Of Signal Transduction Negative Regulation Of Signaling Viral Process Protein Polyubiquitination Ubiquitin-dependent Protein Catabolic Process Via The Multivesicular Body Sorting Pathway Regulation Of Cellular Response To Growth Factor Stimulus Nucleotide-binding Oligomerization Domain Containing Signaling Pathway Intracellular Receptor Signaling Pathway Regulation Of Potassium Ion Transmembrane Transporter Activity Positive Regulation Of Protein Catabolic Process Protein Monoubiquitination Nucleotide-binding Domain, Leucine Rich Repeat Containing Receptor Signaling Pathway Regulation Of Sequence-specific DNA Binding Transcription Factor Activity Regulation Of Transcription From RNA Polymerase II Promoter In Response To Stress Response To Metal Ion Toll-like Receptor 5 Signaling Pathway Toll-like Receptor 10 Signaling Pathway Regulation Of DNA-templated Transcription In Response To Stress I-kappaB Kinase/NF-kappaB Signaling Toll-like Receptor TLR6:TLR2 Signaling Pathway Toll-like Receptor TLR1:TLR2 Signaling Pathway Toll-like Receptor 2 Signaling Pathway Protein Ubiquitination Involved In Ubiquitin-dependent Protein Catabolic Process Toll-like Receptor 9 Signaling Pathway TRIF-dependent Toll-like Receptor Signaling Pathway Regulation Of Sodium Ion Transport MyD88-independent Toll-like Receptor Signaling Pathway Toll-like Receptor 3 Signaling Pathway Regulation Of Protein Catabolic Process Negative Regulation Of Transforming Growth Factor Beta Receptor Signaling Pathway MyD88-dependent Toll-like Receptor Signaling Pathway Regulation Of Ion Transmembrane Transport Regulation Of Protein Metabolic Process Positive Regulation Of Type I Interferon Production Toll-like Receptor 4 Signaling Pathway Negative Regulation Of Transcription From RNA Polymerase II Promoter In Response To UV-induced DNA Damage Histone H3-R2 Demethylation Histone H4-R3 Demethylation Peptidyl-lysine Hydroxylation To 5-hydroxy-L-lysine Muscle Cell Fate Specification Transmission Of Virus Development Involved In Symbiotic Interaction Regulation Of Striated Muscle Contraction JNK Cascade Response To Inorganic Substance Positive Regulation Of Protein Metabolic Process
Tagcloud ?		acinus arginine auxiliary bona definition exerts exon fide hydroxylate localises luc7 luc7l3 modifies modulator modulatory nascent oxoglutarate oxygenase plasmid punctually reporter rs splice splicing sr srsf1 srsf11 u2 u2af65	acd bi boundaries characterised congenita dc directional dkc1 dyskeratosis dystrophic ex1 ex9 exceedingly inherited intron leukoplakia nails nop10 pigmentation pot1 shelterin sixteen telomeres terc terf1 terf2 terf2ip tert tinf2
Tagcloud (Difference) ?		acinus arginine auxiliary bona definition exerts exon fide hydroxylate localises luc7 luc7l3 modifies modulator modulatory nascent oxoglutarate oxygenase plasmid punctually reporter rs splice splicing sr srsf1 srsf11 u2 u2af65	acd bi boundaries characterised congenita dc directional dkc1 dyskeratosis dystrophic ex1 ex9 exceedingly inherited intron leukoplakia nails nop10 pigmentation pot1 shelterin sixteen telomeres terc terf1 terf2 terf2ip tert tinf2
Tagcloud (Intersection) ?