JMJD6 and SLFN12

Number of citations of the paper that reports this interaction (PMID 23455924)
3

Data Source:
BioGRID (two hybrid)

		JMJD6	SLFN12
Gene Name		jumonji domain containing 6	schlafen family member 12
Image			No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleus Nucleoplasm Nucleolus Plasma Membrane
	Molecular Function	RNA Binding Single-stranded RNA Binding Receptor Activity Iron Ion Binding Protein Binding Histone Demethylase Activity (H3-R2 Specific) Histone Demethylase Activity (H4-R3 Specific) Identical Protein Binding Peptidyl-lysine 5-dioxygenase Activity	ATP Binding
	Biological Process	Kidney Development Sprouting Angiogenesis Transcription, DNA-templated Regulation Of Transcription, DNA-templated MRNA Processing Cell Surface Receptor Signaling Pathway Heart Development RNA Splicing Peptidyl-lysine Hydroxylation To 5-hydroxy-L-lysine Lung Development T Cell Differentiation In Thymus Macrophage Activation Recognition Of Apoptotic Cell Regulation Of MRNA Splicing, Via Spliceosome Erythrocyte Development Oxidation-reduction Process Retina Development In Camera-type Eye Histone H3-R2 Demethylation Histone H4-R3 Demethylation
Pathways
Drugs
Diseases
GWAS		Retinal arteriolar caliber ( 23776548)
Protein-Protein Interactions		28 interactors: AEBP2 ANKEF1 BRD4 C17orf97 CCNL1 CENPL DIP2A FAM9A FGD5 FRMD6 GNA14 HIST1H2BJ HMGXB4 LARP7 NAA50 NFIX NHP2 PRPF38A PSMC1 RSPO2 RSRC1 SLFN12 SLU7 STAC3 TAF1A U2AF1 ZCCHC17 ZNF451	2 interactors: JMJD6 SUV39H1
Entrez ID		23210	55106
HPRD ID		05371	08543
Ensembl ID		ENSG00000070495	ENSG00000172123
Uniprot IDs		Q6NYC1	Q8IYM2
PDB IDs		3K2O 3LD8 3LDB
Enriched GO Terms of Interacting Partners?		Chromatin Organization RNA Processing RNA Metabolic Process Gene Expression Chromosome Organization Alternative MRNA Splicing, Via Spliceosome Nucleosome Assembly Chromatin Modification Cellular Nitrogen Compound Metabolic Process Chromatin Assembly RNA Splicing Nucleosome Organization Chromatin Assembly Or Disassembly G1/S Transition Of Mitotic Cell Cycle Nucleobase-containing Compound Metabolic Process Protein-DNA Complex Assembly Mitotic Cell Cycle MRNA Processing Chromatin Remodeling DNA Packaging Nitrogen Compound Metabolic Process Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Mitotic Sister Chromatid Cohesion, Centromeric RRNA Pseudouridine Synthesis Histone H4 Acetylation MRNA Splicing, Via Spliceosome RNA Splicing, Via Transesterification Reactions MRNA Metabolic Process Regulation Of Phosphorylation Of RNA Polymerase II C-terminal Domain Mitotic Cell Cycle Phase Transition Cell Cycle Phase Transition DNA-templated Transcription, Termination Negative Regulation Of Gene Expression, Epigenetic DNA Conformation Change Regulation Of Wnt Signaling Pathway Cellular Macromolecular Complex Assembly Negative Regulation Of DNA Damage Checkpoint Apical Constriction Lung Growth Histone H3-K14 Acetylation Mitotic Cell Cycle Process MRNA 3'-splice Site Recognition Transcription, DNA-templated Histone Acetylation Trachea Cartilage Morphogenesis Internal Peptidyl-lysine Acetylation Positive Regulation Of Canonical Wnt Signaling Pathway Peptidyl-lysine Acetylation Internal Protein Amino Acid Acetylation	Histone H3-R2 Demethylation Histone H4-R3 Demethylation Peptidyl-lysine Hydroxylation To 5-hydroxy-L-lysine Peptidyl-lysine Modification Histone Modification Histone H3-K9 Dimethylation Recognition Of Apoptotic Cell Chromatin Modification Histone H3-K9 Trimethylation Chromatin Organization Peptidyl-lysine Dimethylation Chromatin Silencing At RDNA Phagocytosis, Recognition Peptidyl-amino Acid Modification Negative Regulation Of Circadian Rhythm Histone H3-K9 Methylation Chromosome Organization Peptidyl-lysine Trimethylation Protein Hydroxylation Macrophage Activation Apoptotic Cell Clearance Chromatin Silencing Histone Demethylation Histone H3-K9 Modification Protein Demethylation Erythrocyte Development Sprouting Angiogenesis Demethylation Regulation Of MRNA Splicing, Via Spliceosome T Cell Differentiation In Thymus Negative Regulation Of Gene Expression, Epigenetic Regulation Of MRNA Processing Histone Lysine Methylation Regulation Of Circadian Rhythm Peptidyl-lysine Methylation Cellular Response To Hypoxia Cellular Response To Decreased Oxygen Levels Regulation Of RNA Splicing Gene Silencing Erythrocyte Differentiation Cellular Response To Oxygen Levels Transcription, DNA-templated Erythrocyte Homeostasis Histone Methylation RNA Biosynthetic Process Cell Recognition RRNA Processing RRNA Metabolic Process Myeloid Cell Homeostasis T Cell Differentiation
Tagcloud ?		acinus arginine auxiliary bona definition exerts exon fide hydroxylate localises luc7 luc7l3 modifies modulator modulatory nascent oxoglutarate oxygenase plasmid punctually reporter rs splice splicing sr srsf1 srsf11 u2 u2af65
Tagcloud (Difference) ?		acinus arginine auxiliary bona definition exerts exon fide hydroxylate localises luc7 luc7l3 modifies modulator modulatory nascent oxoglutarate oxygenase plasmid punctually reporter rs splice splicing sr srsf1 srsf11 u2 u2af65
Tagcloud (Intersection) ?