CD93 and MBL2

Number of citations of the paper that reports this interaction (PMID 9476117)
16

Data Source:
HPRD (in vitro)

		CD93	MBL2
Gene Name		CD93 molecule	mannose-binding lectin (protein C) 2, soluble
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Plasma Membrane Cell Surface Integral Component Of Membrane Cytoplasmic Membrane-bounded Vesicle	Extracellular Region Collagen Trimer Extracellular Space Cell Surface
	Molecular Function	Complement Component C1q Binding Receptor Activity Calcium Ion Binding Protein Binding Carbohydrate Binding	Receptor Binding Calcium Ion Binding Protein Binding Mannose Binding Calcium-dependent Protein Binding
	Biological Process	Phagocytosis Viral Process Single Organismal Cell-cell Adhesion Macrophage Activation	Complement Activation, Lectin Pathway Acute-phase Response Complement Activation Complement Activation, Classical Pathway Response To Oxidative Stress Opsonization Defense Response To Bacterium Negative Regulation Of Growth Of Symbiont In Host Innate Immune Response Negative Regulation Of Viral Process Positive Regulation Of Phagocytosis Defense Response To Gram-positive Bacterium Killing By Host Of Symbiont Cells
Pathways			Creation of C4 and C2 activators Complement cascade Initial triggering of complement Lectin pathway of complement activation Innate Immune System
Drugs
Diseases
GWAS		Obesity-related traits ( 23251661)	Age-related macular degeneration ( 23326517) Bone mineral density ( 22504420)
Protein-Protein Interactions		23 interactors: ARHGAP15 BAG6 C1QA COL1A1 COL1A2 COL4A1 COL4A2 COL4A3 COL4A4 COL4A5 COL4A6 COPS5 F12 FAM46A GIPC1 KIR2DL2 KNG1 MBL2 MSN MYD88 RANBP1 SCYL1 UBQLN2	8 interactors: CALCR CALR CD93 KRT1 MAD2L1 MASP1 MASP2 PTPRC
Entrez ID		22918	4153
HPRD ID		00396	01107
Ensembl ID		ENSG00000125810	ENSG00000165471
Uniprot IDs		Q9NPY3	P11226 Q5SQS3
PDB IDs			1HUP
Enriched GO Terms of Interacting Partners?		Collagen Catabolic Process Collagen Metabolic Process Multicellular Organismal Macromolecule Metabolic Process Multicellular Organismal Metabolic Process Extracellular Matrix Disassembly Extracellular Matrix Organization Extracellular Structure Organization Locomotion Movement Of Cell Or Subcellular Component Catabolic Process Protein Activation Cascade Axon Guidance Cellular Response To Amino Acid Stimulus Vesicle-mediated Transport Regulation Of Protein Processing Protein Heterotrimerization Axonogenesis Glomerular Basement Membrane Development Blood Coagulation, Intrinsic Pathway Regulation Of Blood Coagulation Response To External Stimulus Axon Development Response To Amino Acid Cell Morphogenesis Involved In Neuron Differentiation Chemotaxis Renal System Development Regulation Of Wound Healing Neuron Projection Morphogenesis Response To Stimulus Negative Regulation Of Proteolysis Endocytosis Receptor-mediated Endocytosis Negative Regulation Of Growth Of Symbiont In Host Negative Regulation Of Protein Processing Establishment Of Endothelial Barrier Urogenital System Development Cell Morphogenesis Involved In Differentiation Immune System Process Protein Trimerization Cellular Response To Acid Chemical Blood Coagulation Inflammatory Response Hemostasis Immunoglobulin Mediated Immune Response B Cell Mediated Immunity Cellular Response To Transforming Growth Factor Beta Stimulus Response To Transforming Growth Factor Beta Platelet Activation Neuron Projection Development Cell Projection Morphogenesis	Complement Activation, Lectin Pathway Positive Regulation Of Immune System Process Complement Activation Immune System Process Protein Activation Cascade Regulation Of Immune System Process Positive Regulation Of Immune Response Endocytosis Humoral Immune Response Cellular Calcium Ion Homeostasis Regulation Of Immune Response Chemical Homeostasis Calcium Ion Homeostasis Negative Regulation Of Protein Metabolic Process Regulation Of Humoral Immune Response Receptor-mediated Endocytosis Cellular Metal Ion Homeostasis Cellular Cation Homeostasis Peptide Antigen Assembly With MHC Class I Protein Complex Cellular Ion Homeostasis Metal Ion Homeostasis Cellular Chemical Homeostasis Defense Response Homeostatic Process Immunoglobulin Biosynthetic Process Positive Regulation Of Hematopoietic Stem Cell Migration Ion Homeostasis Vesicle-mediated Transport Negative Regulation Of Immune Response Positive Regulation Of DNA Metabolic Process Positive Regulation Of Cytosolic Calcium Ion Concentration Cellular Homeostasis Negative Regulation Of APC-Cdc20 Complex Activity Sequestering Of Calcium Ion Cytosolic Calcium Ion Homeostasis Positive Regulation Of Mitotic Cell Cycle Spindle Assembly Checkpoint Negative Regulation Of T Cell Mediated Cytotoxicity Innate Immune Response Negative Regulation Of Cellular Protein Metabolic Process Positive Regulation Of Dendritic Cell Chemotaxis Positive Regulation Of Humoral Immune Response Mediated By Circulating Immunoglobulin Positive Regulation Of Spindle Checkpoint Positive Regulation Of Isotype Switching To IgG Isotypes Bone Marrow Development Response To Stress Glucocorticoid Receptor Signaling Pathway Protein Metabolic Process Regulation Of Cell Cycle Regulation Of Cell Division Positive Regulation Of Gamma-delta T Cell Differentiation
Tagcloud ?		29a 29b 29c acp5 calcitonin calcr cdc42 commitment concert cytoskeletal gpr85 gtpase hypothesize mir monocytic multinucleated nfia osteoclast osteoclastic osteoclasts raw264 rnas robo slit sponge srgap2 tartrate tempo transduced	32p alkali arises cytoskeletal detergent distinctive encode enzymatic heavily incubation insoluble labelled lstra membranous mo moloney momulv mulv murine phosphoproteins phosphorylate pp60src reflecting sarcoma shares transformed transforming view viruses
Tagcloud (Difference) ?		29a 29b 29c acp5 calcitonin calcr cdc42 commitment concert gpr85 gtpase hypothesize mir monocytic multinucleated nfia osteoclast osteoclastic osteoclasts raw264 rnas robo slit sponge srgap2 tartrate tempo transduced	32p alkali arises detergent distinctive encode enzymatic heavily incubation insoluble labelled lstra membranous mo moloney momulv mulv murine phosphoproteins phosphorylate pp60src reflecting sarcoma shares transformed transforming view viruses
Tagcloud (Intersection) ?		cytoskeletal