CD93 and COL4A1

Number of citations of the paper that reports this interaction (PMID 1377218)
2

Data Source:
HPRD (in vitro)

		CD93	COL4A1
Gene Name		CD93 molecule	collagen, type IV, alpha 1
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Plasma Membrane Cell Surface Integral Component Of Membrane Cytoplasmic Membrane-bounded Vesicle	Extracellular Region Collagen Type IV Trimer Basement Membrane Endoplasmic Reticulum Lumen Extracellular Matrix
	Molecular Function	Complement Component C1q Binding Receptor Activity Calcium Ion Binding Protein Binding Carbohydrate Binding	Extracellular Matrix Structural Constituent Protein Binding Extracellular Matrix Constituent Conferring Elasticity Platelet-derived Growth Factor Binding
	Biological Process	Phagocytosis Viral Process Single Organismal Cell-cell Adhesion Macrophage Activation	Patterning Of Blood Vessels Receptor-mediated Endocytosis Axon Guidance Brain Development Neuromuscular Junction Development Extracellular Matrix Disassembly Extracellular Matrix Organization Collagen Catabolic Process Epithelial Cell Differentiation Blood Vessel Morphogenesis Retinal Blood Vessel Morphogenesis Renal Tubule Morphogenesis Cellular Response To Amino Acid Stimulus Basement Membrane Organization
Pathways			Signaling by PDGF NCAM1 interactions Collagen formation Axon guidance Collagen degradation Anchoring fibril formation Non-integrin membrane-ECM interactions Degradation of the extracellular matrix Assembly of collagen fibrils and other multimeric structures Laminin interactions ECM proteoglycans Integrin cell surface interactions Collagen biosynthesis and modifying enzymes NCAM signaling for neurite out-growth Scavenging by Class A Receptors
Drugs
Diseases
GWAS		Obesity-related traits ( 23251661)	Arterial stiffness ( 20031579) Coronary heart disease ( 21378990) Obesity-related traits ( 23251661)
Protein-Protein Interactions		23 interactors: ARHGAP15 BAG6 C1QA COL1A1 COL1A2 COL4A1 COL4A2 COL4A3 COL4A4 COL4A5 COL4A6 COPS5 F12 FAM46A GIPC1 KIR2DL2 KNG1 MBL2 MSN MYD88 RANBP1 SCYL1 UBQLN2	27 interactors: ACHE APCS APP BMP3 CD93 COL4A2 COL7A1 DCN DISC1 FBLN2 FN1 HABP2 MAG MATN2 MMP9 NID1 NID2 OSM PDGFA PDGFB SAA1 SAA2 SAA4 SERPINE2 SMAD1 TGFBI THBS1
Entrez ID		22918	1282
HPRD ID		00396	00359
Ensembl ID		ENSG00000125810	ENSG00000187498
Uniprot IDs		Q9NPY3	P02462
PDB IDs			1LI1
Enriched GO Terms of Interacting Partners?		Collagen Catabolic Process Collagen Metabolic Process Multicellular Organismal Macromolecule Metabolic Process Multicellular Organismal Metabolic Process Extracellular Matrix Disassembly Extracellular Matrix Organization Extracellular Structure Organization Locomotion Movement Of Cell Or Subcellular Component Catabolic Process Protein Activation Cascade Axon Guidance Cellular Response To Amino Acid Stimulus Vesicle-mediated Transport Regulation Of Protein Processing Protein Heterotrimerization Axonogenesis Glomerular Basement Membrane Development Blood Coagulation, Intrinsic Pathway Regulation Of Blood Coagulation Response To External Stimulus Axon Development Response To Amino Acid Cell Morphogenesis Involved In Neuron Differentiation Chemotaxis Renal System Development Regulation Of Wound Healing Neuron Projection Morphogenesis Response To Stimulus Negative Regulation Of Proteolysis Endocytosis Receptor-mediated Endocytosis Negative Regulation Of Growth Of Symbiont In Host Negative Regulation Of Protein Processing Establishment Of Endothelial Barrier Urogenital System Development Cell Morphogenesis Involved In Differentiation Immune System Process Protein Trimerization Cellular Response To Acid Chemical Blood Coagulation Inflammatory Response Hemostasis Immunoglobulin Mediated Immune Response B Cell Mediated Immunity Cellular Response To Transforming Growth Factor Beta Stimulus Response To Transforming Growth Factor Beta Platelet Activation Neuron Projection Development Cell Projection Morphogenesis	Extracellular Matrix Organization Extracellular Structure Organization Response To Wounding Wound Healing Acute-phase Response Extracellular Matrix Disassembly Tissue Development Blood Coagulation Platelet Degranulation Hemostasis Acute Inflammatory Response Multicellular Organismal Development System Development Cell Adhesion Anatomical Structure Development Locomotion Platelet Activation Response To Stress Endodermal Cell Differentiation Regulation Of Body Fluid Levels Developmental Process Formation Of Primary Germ Layer Regulation Of Wound Healing Inflammatory Response Endoderm Formation Anatomical Structure Morphogenesis Negative Regulation Of Platelet Activation Negative Regulation Of Wound Healing Organ Development Defense Response Negative Regulation Of Phosphatidylinositol Biosynthetic Process Gastrulation Cell Migration Movement Of Cell Or Subcellular Component Endoderm Development Chemotaxis Positive Regulation Of Metanephric Mesenchymal Cell Migration Positive Regulation Of Metanephric Mesenchymal Cell Migration By Platelet-derived Growth Factor Receptor-beta Signaling Pathway Cell Differentiation Regulation Of Blood Coagulation Regulation Of Platelet Activation Cell Motility Response To Stimulus Leukocyte Migration Connective Tissue Development Blood Vessel Morphogenesis Negative Regulation Of Phospholipid Biosynthetic Process Cell Activation Immune System Process Regulation Of Protein Metabolic Process
Tagcloud ?		29a 29b 29c acp5 calcitonin calcr cdc42 commitment concert cytoskeletal gpr85 gtpase hypothesize mir monocytic multinucleated nfia osteoclast osteoclastic osteoclasts raw264 rnas robo slit sponge srgap2 tartrate tempo transduced	arteriopathy autosomal cadasil cavitary confirms eif2b encountered entity excluded fifty frequencies heterogeneous increasingly infancy infarcts inherited leukoencephalopathies leukoencephalopathy magnetic matter onset oriented realized resonance subcortical symmetrical systematic underestimated white
Tagcloud (Difference) ?		29a 29b 29c acp5 calcitonin calcr cdc42 commitment concert cytoskeletal gpr85 gtpase hypothesize mir monocytic multinucleated nfia osteoclast osteoclastic osteoclasts raw264 rnas robo slit sponge srgap2 tartrate tempo transduced	arteriopathy autosomal cadasil cavitary confirms eif2b encountered entity excluded fifty frequencies heterogeneous increasingly infancy infarcts inherited leukoencephalopathies leukoencephalopathy magnetic matter onset oriented realized resonance subcortical symmetrical systematic underestimated white
Tagcloud (Intersection) ?