FARSA and HNRNPR

Number of citations of the paper that reports this interaction (PMID 16169070)
531

Data Source:
HPRD (two hybrid)

		FARSA	HNRNPR
Gene Name		phenylalanyl-tRNA synthetase, alpha subunit	heterogeneous nuclear ribonucleoprotein R
Image
Gene Ontology Annotations	Cellular Component	Cytoplasm Cytosol Membrane	Nucleoplasm Spliceosomal Complex Nucleolus Cytoplasm Ribonucleoprotein Complex Catalytic Step 2 Spliceosome
	Molecular Function	TRNA Binding Phenylalanine-tRNA Ligase Activity Protein Binding ATP Binding Poly(A) RNA Binding	Nucleotide Binding RNA Binding Protein Binding Poly(A) RNA Binding
	Biological Process	TRNA Aminoacylation For Protein Translation Phenylalanyl-tRNA Aminoacylation Gene Expression	MRNA Splicing, Via Spliceosome MRNA Processing RNA Splicing Gene Expression
Pathways		Cytosolic tRNA aminoacylation tRNA Aminoacylation	Processing of Capped Intron-Containing Pre-mRNA mRNA Splicing mRNA Splicing - Major Pathway
Drugs		L-Phenylalanine
Diseases
GWAS		Red blood cell traits ( 23222517)
Protein-Protein Interactions		8 interactors: A2M ABI3 APOE ECSIT GORAB HNRNPR RNF32 TDGF1	9 interactors: BMPR2 FARSA HIST3H3 IL7R KHDRBS2 PRMT1 RPL26 SMN1 TAB1
Entrez ID		2193	10236
HPRD ID		04227	06228
Ensembl ID		ENSG00000179115	ENSG00000125944
Uniprot IDs		B4E363 Q6IBR2 Q9Y285	B4DT28 E7ETM7 O43390 Q0VGD6 Q6MZS5 S4R3J4
PDB IDs		3L4G	2DK2
Enriched GO Terms of Interacting Partners?		BMP Signaling Pathway Regulation Of Oxidoreductase Activity Positive Regulation Of Low-density Lipoprotein Particle Receptor Catabolic Process Positive Regulation Of Dendritic Spine Maintenance Negative Regulation Of Dendritic Spine Maintenance Negative Regulation Of Phospholipid Efflux Negative Regulation Of Lipid Transport Across Blood Brain Barrier Positive Regulation Of Lipid Transport Across Blood Brain Barrier Positive Regulation Of Postsynaptic Membrane Organization Negative Regulation Of Postsynaptic Membrane Organization Regulation Of Cell Migration Regulation Of Endothelial Cell Migration Regulation Of Cell Motility Regulation Of Locomotion Regulation Of Cellular Component Movement Positive Regulation Of Neurofibrillary Tangle Assembly Negative Regulation Of Complement Activation, Lectin Pathway Negative Regulation Of Presynaptic Membrane Organization Positive Regulation Of Presynaptic Membrane Organization Regulation Of Epithelial Cell Migration Positive Regulation Of Phospholipid Efflux Negative Regulation Of Cholesterol Biosynthetic Process Regulation Of Postsynaptic Membrane Organization Very-low-density Lipoprotein Particle Clearance Gastrulation Regulation Of Low-density Lipoprotein Particle Receptor Catabolic Process Regulation Of Tau-protein Kinase Activity Negative Regulation Of Cholesterol Efflux N-methyl-D-aspartate Receptor Clustering Regulation Of Presynaptic Membrane Organization Regulation Of Catalytic Activity Negative Regulation Of Dendritic Spine Development High-density Lipoprotein Particle Clearance Transmembrane Receptor Protein Serine/threonine Kinase Signaling Pathway Regulation Of Beta-amyloid Clearance Positive Regulation Of Inclusion Body Assembly Very-low-density Lipoprotein Particle Remodeling Positive Regulation Of Cholesterol Esterification Alpha-amino-3-hydroxy-5-methyl-4-isoxazole Propionate Selective Glutamate Receptor Clustering High-density Lipoprotein Particle Assembly Regulation Of Inflammatory Response Cellular Response To Hepatocyte Growth Factor Stimulus Positive Regulation Of Phospholipid Transport Chylomicron Remnant Clearance Regulation Of MAP Kinase Activity Regulation Of Cholesterol Esterification Peripheral Nervous System Axon Regeneration Triglyceride-rich Lipoprotein Particle Remodeling Stem Cell Differentiation CGMP-mediated Signaling	NcRNA Metabolic Process Interleukin-7-mediated Signaling Pathway Regulation Of Lung Blood Pressure Negative Regulation Of Chondrocyte Proliferation
Tagcloud ?			absent alleles aml atlas australasian bank box conjunction enrichment epigenetic frequently hypermethylation leukemic marks matr3 promoter sf3a1 sf3b1 silence silico somatic splicing srsf2 suppressing u2af1 u937 ybx3 zfr zrsr2
Tagcloud (Difference) ?			absent alleles aml atlas australasian bank box conjunction enrichment epigenetic frequently hypermethylation leukemic marks matr3 promoter sf3a1 sf3b1 silence silico somatic splicing srsf2 suppressing u2af1 u937 ybx3 zfr zrsr2
Tagcloud (Intersection) ?