ALAS2 and RABGGTB

Number of citations of the paper that reports this interaction (PMID 546546)
0

Data Source:
HPRD (in vivo)

		ALAS2	RABGGTB
Gene Name		5-aminolevulinate synthase 2	Rab geranylgeranyltransferase, beta subunit
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Mitochondrion Mitochondrial Inner Membrane Mitochondrial Matrix	Rab-protein Geranylgeranyltransferase Complex
	Molecular Function	5-aminolevulinate Synthase Activity Protein Binding Glycine Binding Pyridoxal Phosphate Binding Coenzyme Binding	Rab Geranylgeranyltransferase Activity Protein Binding Zinc Ion Binding Rab GTPase Binding
	Biological Process	Response To Hypoxia Porphyrin-containing Compound Metabolic Process Protoporphyrinogen IX Biosynthetic Process Heme Biosynthetic Process Cellular Iron Ion Homeostasis Erythrocyte Differentiation Oxygen Homeostasis Hemoglobin Biosynthetic Process Small Molecule Metabolic Process	Cellular Protein Modification Process Visual Perception Protein Geranylgeranylation
Pathways		Heme biosynthesis Metabolism of porphyrins
Drugs		Glycine
Diseases
GWAS
Protein-Protein Interactions		4 interactors: BANP GRB2 RABGGTB SUCLA2	16 interactors: ALAS2 ARAF B4GALT7 CHML FAM19A1 PTP4A2 RAB11A RAB1A RAB27A RAB37 RAB3A RAB5A RAB6A RAB7A TMEM25 WDR4
Entrez ID		212	5876
HPRD ID		02356	01532
Ensembl ID		ENSG00000158578	ENSG00000137955
Uniprot IDs		P22557	A8KAJ2 P53611 Q6IB63
PDB IDs
Enriched GO Terms of Interacting Partners?		Succinyl-CoA Pathway Uroporphyrinogen III Biosynthetic Process	Rab Protein Signal Transduction Ras Protein Signal Transduction Intracellular Protein Transport Small GTPase Mediated Signal Transduction Cellular Protein Localization Protein Transport Establishment Of Protein Localization Regulation Of Exocytosis Intracellular Transport Regulation Of Vesicle-mediated Transport Positive Regulation Of Exocytosis Establishment Of Vesicle Localization Vesicle Localization Intracellular Signal Transduction Protein Localization Membrane Docking Establishment Of Localization In Cell Multivesicular Body Organization Vesicle-mediated Transport Protein Secretion Melanosome Transport Pigment Granule Transport Establishment Of Organelle Localization Establishment Of Melanosome Localization Regulation Of Endosome Size Melanosome Localization Cellular Localization Exosomal Secretion Organelle Localization Regulation Of Neuronal Synaptic Plasticity Cellular Pigmentation Endosomal Transport Vesicle Docking Involved In Exocytosis Secretion By Cell Vesicle Docking Secretion Regulation Of Secretion Positive Regulation Of Secretion Synaptic Vesicle Transport Cytoplasmic Transport Exocytosis Pigmentation Positive Regulation Of Regulated Secretory Pathway Early Endosome To Late Endosome Transport Endomembrane System Organization Regulation Of Synaptic Plasticity Regulation Of Long-term Neuronal Synaptic Plasticity Endosome Organization Regulation Of Synaptic Vesicle Exocytosis Synaptic Vesicle Recycling
Tagcloud ?		abcb7 advance asxl1 bclaf1 brca1 causal cbl cd34 december deregulation disruption doi erythroid exon hnrnpd leu link online pathophysiology prpf8 publication rars refractory sf3b1 sideroblasts slc25a37 splicing transcript transcriptome
Tagcloud (Difference) ?		abcb7 advance asxl1 bclaf1 brca1 causal cbl cd34 december deregulation disruption doi erythroid exon hnrnpd leu link online pathophysiology prpf8 publication rars refractory sf3b1 sideroblasts slc25a37 splicing transcript transcriptome
Tagcloud (Intersection) ?