FBL and PRMT3

Number of citations of the paper that reports this interaction (PMID 16157300)
14

Data Source:
BioGRID (enzymatic study)

		FBL	PRMT3
Gene Name		fibrillarin	protein arginine methyltransferase 3
Image
Gene Ontology Annotations	Cellular Component	Granular Component Nucleus Nucleolus Cajal Body Membrane Box C/D SnoRNP Complex Extracellular Vesicular Exosome	Cytoplasm Cytosol Ribosome
	Molecular Function	RNA Binding Protein Binding Poly(A) RNA Binding Histone-glutamine Methyltransferase Activity	Protein Binding Methyltransferase Activity Histone-arginine N-methyltransferase Activity Protein-arginine N-methyltransferase Activity Protein-arginine Omega-N Asymmetric Methyltransferase Activity Metal Ion Binding Modified Amino Acid Binding
	Biological Process	Osteoblast Differentiation RRNA Processing TRNA Processing SnoRNA Metabolic Process Histone Glutamine Methylation	Regulation Of Transcription, DNA-templated Peptidyl-arginine Methylation, To Asymmetrical-dimethyl Arginine Negative Regulation Of Protein Ubiquitination Histone Arginine Methylation
Pathways
Drugs
Diseases
GWAS
Protein-Protein Interactions		19 interactors: DDX17 DDX5 ERG KLF6 MAP3K14 NOP56 PIH1D1 PIN4 PRMT1 PRMT3 PRMT6 PSMB6 RUVBL1 RUVBL2 SMN1 SMN2 SNRPN TAF9 TBC1D17	7 interactors: FBL HNRNPA1 PABPN1 PPARD RASSF2 RPS2 STAT1
Entrez ID		2091	10196
HPRD ID		00617	11934
Ensembl ID		ENSG00000105202	ENSG00000185238
Uniprot IDs		P22087	O60678 Q8WUV3
PDB IDs		2IPX	2FYT 3SMQ 4HSG
Enriched GO Terms of Interacting Partners?		Peptidyl-arginine Methylation, To Asymmetrical-dimethyl Arginine RNA Metabolic Process Peptidyl-arginine N-methylation Peptidyl-amino Acid Modification Histone Arginine Methylation Peptidyl-arginine Methylation Histone Modification Cellular Nitrogen Compound Metabolic Process Gene Expression Cellular Metabolic Process Nucleobase-containing Compound Metabolic Process Nitrogen Compound Metabolic Process Ribonucleoprotein Complex Biogenesis Chromatin Modification Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Positive Regulation Of Intracellular Estrogen Receptor Signaling Pathway Chromatin Organization Positive Regulation Of Intracellular Steroid Hormone Receptor Signaling Pathway Histone H4-R3 Methylation Cellular Protein Modification Process Histone H2A Acetylation RNA Processing Chromosome Organization Regulation Of Skeletal Muscle Cell Differentiation Histone Acetylation Histone Methylation Internal Peptidyl-lysine Acetylation Peptidyl-lysine Acetylation Internal Protein Amino Acid Acetylation RNA Splicing Protein Acetylation Regulation Of Intracellular Estrogen Receptor Signaling Pathway Transcription, DNA-templated RNA Biosynthetic Process Protein Methylation Ribonucleoprotein Complex Assembly Regulation Of Nitrogen Compound Metabolic Process Cellular Response To DNA Damage Stimulus Metabolic Process NcRNA Metabolic Process Spliceosomal SnRNP Assembly Regulation Of Signal Transduction By P53 Class Mediator Regulation Of Transcription, DNA-templated Regulation Of Nucleic Acid-templated Transcription Cellular Protein Metabolic Process Regulation Of RNA Biosynthetic Process MRNA Splicing, Via Spliceosome RNA Splicing, Via Transesterification Reactions Histone H4 Acetylation	Viral Process RNA Metabolic Process RNA Export From Nucleus Negative Regulation Of Macrophage Fusion Epidermal Growth Factor Receptor Signaling Pathway Via I-kappaB Kinase/NF-kappaB Cascade Histone Glutamine Methylation Nucleobase-containing Compound Metabolic Process Regulation Of Smooth Muscle Cell Proliferation MRNA Metabolic Process Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Cellular Nitrogen Compound Metabolic Process Nuclear Export MRNA Transport Negative Regulation By Virus Of Viral Protein Levels In Host Cell Modification By Virus Of Host MRNA Processing Negative Regulation Of Metanephric Nephron Tubule Epithelial Cell Differentiation Peptidyl-glutamine Methylation Negative Regulation Of Epithelial Cell Proliferation RNA Transport Cytoplasmic Transport RNA Localization Negative Regulation Of Nephron Tubule Epithelial Cell Differentiation Metanephric Mesenchymal Cell Proliferation Involved In Metanephros Development Nitrogen Compound Metabolic Process Gene Expression Negative Regulation Of NIK/NF-kappaB Signaling SnoRNA Metabolic Process Viral Life Cycle Metanephric Mesenchymal Cell Differentiation Transcription From RNA Polymerase II Promoter Response To Nutrient Keratinocyte Migration Negative Regulation Of Syncytium Formation By Plasma Membrane Fusion Negative Regulation Of Mesenchymal To Epithelial Transition Involved In Metanephros Morphogenesis MRNA Splicing, Via Spliceosome RNA Splicing, Via Transesterification Reactions Negative Regulation Of Collagen Biosynthetic Process Vitamin A Metabolic Process Nucleocytoplasmic Transport Nuclear Transport Mesenchymal Cell Differentiation Involved In Kidney Development Negative Regulation Of Multicellular Organismal Metabolic Process RNA Biosynthetic Process Ossification Regulation Of Epithelial Cell Proliferation Cell Proliferation Involved In Metanephros Development Regulation Of Mesenchymal To Epithelial Transition Involved In Metanephros Morphogenesis Regulation Of Metanephric Nephron Tubule Epithelial Cell Differentiation Poly(A)+ MRNA Export From Nucleus
Tagcloud ?		actinomycin character condensed contribution delays differentiation es example fibrillarin hyperdynamic interestingly knockdown latter lif lineages methyltransferase nucleolar nucleoli partial pluripotency pluripotent processing prolonged promoted proper ribosomal rrna stem unique	bbrd brucei clade clades connects dart dihydrolipoamide exemplified fmr homologues methyltransferases outgroup paralogue phylogeny prmt1 prmt2 prmt4 prmt5 prmt6 prmt7 prmt8 prmt9 prmts reconstructing resolve tbprmts tedious trypanosoma uncharacterized
Tagcloud (Difference) ?		actinomycin character condensed contribution delays differentiation es example fibrillarin hyperdynamic interestingly knockdown latter lif lineages methyltransferase nucleolar nucleoli partial pluripotency pluripotent processing prolonged promoted proper ribosomal rrna stem unique	bbrd brucei clade clades connects dart dihydrolipoamide exemplified fmr homologues methyltransferases outgroup paralogue phylogeny prmt1 prmt2 prmt4 prmt5 prmt6 prmt7 prmt8 prmt9 prmts reconstructing resolve tbprmts tedious trypanosoma uncharacterized
Tagcloud (Intersection) ?