FBL

Gene Name		fibrillarin
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Gene Ontology Annotations	Cellular Component	Granular Component Nucleus Nucleolus Cajal Body Membrane Box C/D SnoRNP Complex Extracellular Vesicular Exosome
	Molecular Function	RNA Binding Protein Binding Poly(A) RNA Binding Histone-glutamine Methyltransferase Activity
	Biological Process	Osteoblast Differentiation RRNA Processing TRNA Processing SnoRNA Metabolic Process Histone Glutamine Methylation
Pathways
Drugs
Diseases
GWAS
Protein-protein Interactions		19 interactors: DDX17 DDX5 ERG KLF6 MAP3K14 NOP56 PIH1D1 PIN4 PRMT1 PRMT3 PRMT6 PSMB6 RUVBL1 RUVBL2 SMN1 SMN2 SNRPN TAF9 TBC1D17
Entrez ID		2091
HPRD ID		00617
Ensembl ID		ENSG00000105202
Uniprot IDs		P22087
PDB IDs		2IPX
Enriched GO Terms of Interacting Partners?		Peptidyl-arginine Methylation, To Asymmetrical-dimethyl Arginine RNA Metabolic Process Peptidyl-arginine N-methylation Peptidyl-amino Acid Modification Histone Arginine Methylation Peptidyl-arginine Methylation Histone Modification Cellular Nitrogen Compound Metabolic Process Gene Expression Cellular Metabolic Process Nucleobase-containing Compound Metabolic Process Nitrogen Compound Metabolic Process Ribonucleoprotein Complex Biogenesis Chromatin Modification Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Positive Regulation Of Intracellular Estrogen Receptor Signaling Pathway Chromatin Organization Positive Regulation Of Intracellular Steroid Hormone Receptor Signaling Pathway Histone H4-R3 Methylation Cellular Protein Modification Process Histone H2A Acetylation RNA Processing Chromosome Organization Regulation Of Skeletal Muscle Cell Differentiation Histone Acetylation Histone Methylation Internal Peptidyl-lysine Acetylation Peptidyl-lysine Acetylation Internal Protein Amino Acid Acetylation RNA Splicing Protein Acetylation Regulation Of Intracellular Estrogen Receptor Signaling Pathway Transcription, DNA-templated RNA Biosynthetic Process Protein Methylation Ribonucleoprotein Complex Assembly Regulation Of Nitrogen Compound Metabolic Process Cellular Response To DNA Damage Stimulus Metabolic Process NcRNA Metabolic Process Spliceosomal SnRNP Assembly Regulation Of Signal Transduction By P53 Class Mediator Regulation Of Transcription, DNA-templated Regulation Of Nucleic Acid-templated Transcription Cellular Protein Metabolic Process Regulation Of RNA Biosynthetic Process MRNA Splicing, Via Spliceosome RNA Splicing, Via Transesterification Reactions Histone H4 Acetylation
Tagcloud ?		actinomycin character condensed contribution delays differentiation es example fibrillarin hyperdynamic interestingly knockdown latter lif lineages methyltransferase nucleolar nucleoli partial pluripotency pluripotent processing prolonged promoted proper ribosomal rrna stem unique