EPHB6 and EPHB1

Number of citations of the paper that reports this interaction (PMID 11713248)
11

Data Source:
HPRD (in vivo)

		EPHB6	EPHB1
Gene Name		EPH receptor B6	EPH receptor B1
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Extracellular Region Cytosol Plasma Membrane Integral Component Of Plasma Membrane	Extracellular Region Cytosol Plasma Membrane Integral Component Of Plasma Membrane Axon Dendrite Early Endosome Membrane Membrane Raft Extracellular Vesicular Exosome
	Molecular Function	Receptor Activity Ephrin Receptor Activity ATP Binding	Transmembrane-ephrin Receptor Activity Protein Binding ATP Binding Axon Guidance Receptor Activity
	Biological Process	Protein Phosphorylation Axon Guidance Ephrin Receptor Signaling Pathway	Angiogenesis Axon Guidance Peptidyl-tyrosine Phosphorylation Optic Nerve Morphogenesis Central Nervous System Projection Neuron Axonogenesis Neurogenesis Establishment Of Cell Polarity Retinal Ganglion Cell Axon Guidance Cell-substrate Adhesion Regulation Of JNK Cascade Protein Autophosphorylation Ephrin Receptor Signaling Pathway Camera-type Eye Morphogenesis Detection Of Temperature Stimulus Involved In Sensory Perception Of Pain Positive Regulation Of Synapse Assembly Cell Chemotaxis Dendritic Spine Development Dendritic Spine Morphogenesis Neural Precursor Cell Proliferation Regulation Of ERK1 And ERK2 Cascade Regulation Of Neuron Death
Pathways		EPHB-mediated forward signaling Ephrin signaling EPH-ephrin mediated repulsion of cells Axon guidance EPH-Ephrin signaling	EPHB-mediated forward signaling Ephrin signaling EPH-ephrin mediated repulsion of cells Axon guidance EPH-Ephrin signaling
Drugs
Diseases
GWAS			Visceral adipose tissue adjusted for BMI ( 22589738) Visceral adipose tissue/subcutaneous adipose tissue ratio ( 22589738)
Protein-Protein Interactions		15 interactors: CBL CRK CRKL EFNB2 EPHB1 GRB2 HDHD2 INCA1 MLLT4 NIF3L1 NOTCH2NL REL SAT1 TCF4 TRIM39	11 interactors: ACP1 EFNA1 EFNA5 EFNB1 EFNB2 EPHB6 GRB10 GRB2 NCK1 PRKCG PXN
Entrez ID		2051	2047
HPRD ID		04133	02790
Ensembl ID		ENSG00000106123	ENSG00000154928
Uniprot IDs		O15197	P54762
PDB IDs			2DJS 2EAO
Enriched GO Terms of Interacting Partners?		Positive Regulation Of Signal Transduction Regulation Of Signal Transduction Transmembrane Receptor Protein Tyrosine Kinase Signaling Pathway Regulation Of Signaling Regulation Of Intracellular Signal Transduction Enzyme Linked Receptor Protein Signaling Pathway Blood Vessel Development Vasculature Development Ephrin Receptor Signaling Pathway Signaling Cell Communication Positive Regulation Of Intracellular Signal Transduction Cardiovascular System Development Regulation Of Cell Death Cell Surface Receptor Signaling Pathway Signal Transduction Neurotrophin TRK Receptor Signaling Pathway Cellular Response To Stimulus Neurotrophin Signaling Pathway Cellular Response To Growth Factor Stimulus Negative Regulation Of Epidermal Growth Factor Receptor Signaling Pathway Negative Regulation Of ERBB Signaling Pathway Response To Growth Factor Regulation Of MAPK Cascade Regulation Of Cellular Process Activation Of MAPKK Activity Regulation Of Phosphorylation Regulation Of Metabolic Process Regulation Of Epidermal Growth Factor Receptor Signaling Pathway Angiogenesis Regulation Of ERBB Signaling Pathway Spermidine Acetylation Catenin Import Into Nucleus 7,8-dihydroneopterin 3'-triphosphate Biosynthetic Process Canonical Wnt Signaling Pathway Involved In Positive Regulation Of Epithelial To Mesenchymal Transition Regulation Of Protein Metabolic Process Regulation Of Phosphorus Metabolic Process Axon Guidance Positive Regulation Of Heparan Sulfate Proteoglycan Biosynthetic Process Dihydrobiopterin Metabolic Process Putrescine Catabolic Process Cell-cell Signaling Blood Vessel Morphogenesis Response To Stimulus Anatomical Structure Morphogenesis Maintenance Of DNA Repeat Elements Positive Regulation Of Metabolic Process Organ Morphogenesis Response To Organic Substance Oxalate Transport	Transmembrane Receptor Protein Tyrosine Kinase Signaling Pathway Enzyme Linked Receptor Protein Signaling Pathway Axon Guidance Cell Morphogenesis Involved In Differentiation Ephrin Receptor Signaling Pathway Axonogenesis Axon Development Cell Morphogenesis Involved In Neuron Differentiation Chemotaxis Cell Morphogenesis Neuron Projection Morphogenesis Cell Projection Organization Neuron Projection Development Cell Surface Receptor Signaling Pathway Cell Projection Morphogenesis Cell Part Morphogenesis Movement Of Cell Or Subcellular Component Neuron Development Neuron Differentiation Cell Development Locomotion Nervous System Development Generation Of Neurons Anatomical Structure Morphogenesis Neurogenesis Signal Transduction Response To External Stimulus Regulation Of Cell Adhesion Signaling Cell Communication Regulation Of Phosphorylation Regulation Of Cell-cell Adhesion Signal Complex Assembly Multicellular Organismal Development Cell Differentiation Regulation Of Phosphorus Metabolic Process Cell Migration Cellular Response To Stimulus Anatomical Structure Development Cell Motility Cell-cell Signaling Positive Regulation Of Cellular Metabolic Process Epidermal Growth Factor Receptor Signaling Pathway ERBB Signaling Pathway Developmental Process System Development Positive Regulation Of T Cell Activation Cell Adhesion Positive Regulation Of Homotypic Cell-cell Adhesion Positive Regulation Of Signal Transduction
Tagcloud ?		abca1 adamtsl3 aiming apc crc elac1 epha3 ercc6 excluding exome fbxw7 germline kbiosciences marginal mll3 obscn pkhd1 recessive rs4987622 rs6464211 rs6947538 silico smad4 snps somatic spite strongest syne1 trpv6	anlage b3 cascades cortical cue endogenously entering ephrin fak gives interneurons migrate migrating misrouted path pfak poa preoptic psrc repulsion repulsive reverse stop str striatal striatum superficial terminate
Tagcloud (Difference) ?		abca1 adamtsl3 aiming apc crc elac1 epha3 ercc6 excluding exome fbxw7 germline kbiosciences marginal mll3 obscn pkhd1 recessive rs4987622 rs6464211 rs6947538 silico smad4 snps somatic spite strongest syne1 trpv6	anlage b3 cascades cortical cue endogenously entering ephrin fak gives interneurons migrate migrating misrouted path pfak poa preoptic psrc repulsion repulsive reverse stop str striatal striatum superficial terminate
Tagcloud (Intersection) ?