EFNB1 and CAPN10

Number of citations of the paper that reports this interaction (PMID 21988832)
14

Data Source:
BioGRID (two hybrid)

		EFNB1	CAPN10
Gene Name		ephrin-B1	calpain 10
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleus Cytoplasm Plasma Membrane Integral Component Of Plasma Membrane Membrane Raft Synapse Extracellular Vesicular Exosome	Cell Mitochondrion Cytosol Plasma Membrane
	Molecular Function	Protein Binding Ephrin Receptor Binding	SNARE Binding Calcium-dependent Cysteine-type Endopeptidase Activity Cytoskeletal Protein Binding
	Biological Process	Neural Crest Cell Migration Cell Adhesion Cell-cell Signaling Axon Guidance Embryonic Pattern Specification Positive Regulation Of T Cell Proliferation Ephrin Receptor Signaling Pathway	Proteolysis Cellular Component Disassembly Involved In Execution Phase Of Apoptosis Actin Cytoskeleton Reorganization Positive Regulation Of Insulin Secretion Positive Regulation Of Intracellular Transport Cellular Response To Insulin Stimulus Positive Regulation Of Glucose Import Type B Pancreatic Cell Apoptotic Process Positive Regulation Of Type B Pancreatic Cell Apoptotic Process
Pathways		EPHB-mediated forward signaling Ephrin signaling EPH-ephrin mediated repulsion of cells Axon guidance EPH-Ephrin signaling
Drugs
Diseases
GWAS
Protein-Protein Interactions		16 interactors: CAPN10 CUL3 EPHA3 EPHB1 EPHB2 GRIP1 MYC NCK2 PICK1 PTPN13 RGS3 SDCBP SORBS1 SRC TIAM1 YWHAQ	4 interactors: EFNB1 FANCC FLOT1 PSMA7
Entrez ID		1947	11132
HPRD ID		02072	05595
Ensembl ID		ENSG00000090776	ENSG00000142330
Uniprot IDs		P98172	Q9HC96
PDB IDs
Enriched GO Terms of Interacting Partners?		Ephrin Receptor Signaling Pathway Regulation Of Signaling Regulation Of Cellular Component Organization Enzyme Linked Receptor Protein Signaling Pathway Neuron Development Axon Guidance Transmembrane Receptor Protein Tyrosine Kinase Signaling Pathway Cell Morphogenesis Involved In Differentiation Regulation Of Signal Transduction Neuron Differentiation Cell Projection Organization Neuron Projection Development Axonogenesis Cell Development Axon Development Regulation Of Organelle Organization Cell Morphogenesis Involved In Neuron Differentiation Chemotaxis Neuron Projection Morphogenesis Stress Fiber Assembly Cell Morphogenesis Generation Of Neurons Dendritic Spine Organization Neurogenesis Nervous System Development Regulation Of Intracellular Signal Transduction Cell Surface Receptor Signaling Pathway Locomotion Cell Migration Cell Projection Morphogenesis Cell Part Morphogenesis Signal Transduction Cell Motility Cellular Response To Stimulus Positive Regulation Of Cellular Component Biogenesis Apoptotic Process Actin Cytoskeleton Organization Movement Of Cell Or Subcellular Component Signaling Programmed Cell Death Actin Filament-based Process Cell Communication Cell Death Death Multicellular Organismal Development Anatomical Structure Development Positive Regulation Of Organelle Organization Positive Regulation Of Transport Anatomical Structure Morphogenesis Optic Nerve Morphogenesis
Tagcloud ?		allow attenuation cetuximab contribution dimerization disappointing drives egf egfr ephrinb1 erbb1 head hnscc mechanistically mediate neck overexpress partner partners persistent persists rearrangements shift slowed squamous substantial targeted trigger yielded	6c calpain carcinoma cdna clinicopathological clinocopathologcial correction differentially esophageal gaec1 greatest knocking kyse150 microarray microarrays mts normalized oncogene parental prominently psilencer rnai squamous tnrc6c transfected transfecting trinucleotide u133 vector
Tagcloud (Difference) ?		allow attenuation cetuximab contribution dimerization disappointing drives egf egfr ephrinb1 erbb1 head hnscc mechanistically mediate neck overexpress partner partners persistent persists rearrangements shift slowed substantial targeted trigger yielded	6c calpain carcinoma cdna clinicopathological clinocopathologcial correction differentially esophageal gaec1 greatest knocking kyse150 microarray microarrays mts normalized oncogene parental prominently psilencer rnai tnrc6c transfected transfecting trinucleotide u133 vector
Tagcloud (Intersection) ?		squamous