ECM1 and RERE

Number of citations of the paper that reports this interaction (PMID 16713569)
214

Data Source:
BioGRID (two hybrid)
HPRD (two hybrid)

		ECM1	RERE
Gene Name		extracellular matrix protein 1	arginine-glutamic acid dipeptide (RE) repeats
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Proteinaceous Extracellular Matrix Extracellular Space Extracellular Matrix Extracellular Vesicular Exosome	Histone Deacetylase Complex Nucleus
	Molecular Function	Protease Binding Signal Transducer Activity Interleukin-2 Receptor Binding Protein Binding Protein C-terminus Binding Enzyme Binding Laminin Binding	Chromatin Binding Sequence-specific DNA Binding Transcription Factor Activity Protein Binding Poly-glutamine Tract Binding Zinc Ion Binding Sequence-specific DNA Binding
	Biological Process	Ossification Angiogenesis Positive Regulation Of Endothelial Cell Proliferation Negative Regulation Of Cytokine-mediated Signaling Pathway Regulation Of Type 2 Immune Response Regulation Of Transcription From RNA Polymerase II Promoter Inflammatory Response Signal Transduction Negative Regulation Of Peptidase Activity Negative Regulation Of Bone Mineralization Biomineral Tissue Development Positive Regulation Of I-kappaB Kinase/NF-kappaB Signaling Positive Regulation Of Angiogenesis Regulation Of T Cell Migration	Chromatin Remodeling Transcription, DNA-templated Regulation Of Transcription, DNA-templated NLS-bearing Protein Import Into Nucleus Multicellular Organismal Development
Pathways
Drugs
Diseases
GWAS			Autism spectrum disorder, attention deficit-hyperactivity disorder, bipolar disorder, major depressive disorder, and schizophrenia (combined) ( 23453885) Bone mineral density ( 22504420) Vertical cup-disc ratio ( 20548946) Vitiligo ( 20410501)
Protein-Protein Interactions		8 interactors: ATN1 BNIP3L CPTP FBLN1 HSPG2 IRAK3 RERE SRPK1	20 interactors: ALG13 ATN1 CBFA2T2 ECM1 EFEMP1 EFEMP2 EHMT2 HIST2H3C KAT6A KRTAP4-12 LZTR1 NR2E1 PLSCR1 PRRC2A PRRC2B PSMA3 RBFOX2 TRIM22 TRIP6 ZMYND8
Entrez ID		1893	473
HPRD ID		03727	05566
Ensembl ID		ENSG00000143369	ENSG00000142599
Uniprot IDs		Q16610	B1AKN3 Q9P2R6
PDB IDs			2YQK
Enriched GO Terms of Interacting Partners?		Positive Regulation Of Macrophage Tolerance Induction Ceramide 1-phosphate Transport Viral Process Mitochondrial Protein Catabolic Process Negative Regulation Of Macrophage Cytokine Production Ceramide Transport	Regulation Of Nitrogen Compound Metabolic Process Regulation Of Transcription, DNA-templated Regulation Of Nucleic Acid-templated Transcription Negative Regulation Of Cellular Metabolic Process Negative Regulation Of Nucleic Acid-templated Transcription Regulation Of RNA Biosynthetic Process Negative Regulation Of RNA Biosynthetic Process Regulation Of RNA Metabolic Process Negative Regulation Of Biosynthetic Process Regulation Of Gene Expression Negative Regulation Of Transcription, DNA-templated Negative Regulation Of Gene Expression Regulation Of Metabolic Process Gene Expression DNA Methylation On Cytosine Cellular Nitrogen Compound Metabolic Process Regulation Of Cellular Process Regulation Of Transcription From RNA Polymerase II Promoter Positive Regulation Of I-kappaB Kinase/NF-kappaB Signaling Nitrogen Compound Metabolic Process Nucleobase-containing Compound Metabolic Process Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Regulation Of I-kappaB Kinase/NF-kappaB Signaling Transcription, DNA-templated RNA Biosynthetic Process Amygdala Development RNA Metabolic Process DNA Methylation Somatic Stem Cell Maintenance Response To Stress Negative Regulation Of Cell Differentiation Cellular Macromolecule Biosynthetic Process DNA Modification Negative Regulation Of Transcription From RNA Polymerase II Promoter Macromolecule Biosynthetic Process Extracellular Matrix Organization Extracellular Structure Organization Positive Regulation Of DNA Topoisomerase (ATP-hydrolyzing) Activity DNA Methylation On Cytosine Within A CG Sequence Blood Coagulation Hemostasis Radial Glia Guided Migration Of Purkinje Cell Regulation Of Definitive Erythrocyte Differentiation Release Of Cytoplasmic Sequestered NF-kappaB Positive Regulation Of Angiogenesis Regulation Of Cell Differentiation Peptidyl-amino Acid Modification Phosphatidylserine Biosynthetic Process Regulation Of Timing Of Neuron Differentiation
Tagcloud ?		aberration additionally asn condition contrary defect defective derived extracellular glycan glycosylated glycosylation lipoid lp matrix mutants mutated negatively origin proteinosis putative rare residues secretion sites spectrometry suppresses variety wide	antagonism caudal downregulating e8 ectopic embryos exiting extending fgf fgf8 fused h3k27me3 lacz mesoderm neuroectoderm polycomb prc2 ra raldh2 rarb rare rares repress represses repressive somite somites trunk vertebrate
Tagcloud (Difference) ?		aberration additionally asn condition contrary defect defective derived extracellular glycan glycosylated glycosylation lipoid lp matrix mutants mutated negatively origin proteinosis putative residues secretion sites spectrometry suppresses variety wide	antagonism caudal downregulating e8 ectopic embryos exiting extending fgf fgf8 fused h3k27me3 lacz mesoderm neuroectoderm polycomb prc2 ra raldh2 rarb rares repress represses repressive somite somites trunk vertebrate
Tagcloud (Intersection) ?		rare