DSC1 and PKP3

Number of citations of the paper that reports this interaction (PMID 12707304)
37

Data Source:
HPRD (two hybrid)

		DSC1	PKP3
Gene Name		desmocollin 1	plakophilin 3
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Plasma Membrane Gap Junction Membrane Integral Component Of Membrane Desmosome Extracellular Vesicular Exosome	Nucleus Plasma Membrane Cell-cell Junction Desmosome
	Molecular Function	Calcium Ion Binding	Cell Adhesion Molecule Binding
	Biological Process	Homophilic Cell Adhesion Via Plasma Membrane Adhesion Molecules	Desmosome Assembly Single Organismal Cell-cell Adhesion Establishment Of Protein Localization To Plasma Membrane
Pathways
Drugs
Diseases
GWAS		Multiple sclerosis ( 23412934)
Protein-Protein Interactions		8 interactors: DSG1 DSG2 DSP JUP PKP1 PKP2 PKP3 UCHL5	9 interactors: DSC1 DSC2 DSC3 DSG1 DSG2 DSG3 DSP JUP KRT18
Entrez ID		1823	11187
HPRD ID		00511	05711
Ensembl ID		ENSG00000134765	ENSG00000184363
Uniprot IDs		Q08554 Q9HB00	F8J390 Q9Y446
PDB IDs
Enriched GO Terms of Interacting Partners?		Bundle Of His Cell To Purkinje Myocyte Communication Desmosome Organization Ventricular Cardiac Muscle Cell Action Potential Regulation Of Heart Rate By Cardiac Conduction Desmosome Assembly Cardiac Muscle Cell Action Potential Involved In Contraction Cardiac Muscle Cell Action Potential Regulation Of Cardiac Muscle Cell Contraction Cardiac Conduction Cell-cell Junction Organization Cellular Component Disassembly Involved In Execution Phase Of Apoptosis Single Organismal Cell-cell Adhesion Cell Adhesion Execution Phase Of Apoptosis Regulation Of Heart Rate Regulation Of Cardiac Muscle Contraction Action Potential Regulation Of Striated Muscle Contraction Intermediate Filament Organization Cell-cell Junction Assembly Regulation Of Muscle Contraction Regulation Of Heart Contraction Intermediate Filament Cytoskeleton Organization Cell Junction Assembly Intermediate Filament-based Process Regulation Of Membrane Potential Intermediate Filament Bundle Assembly Adherens Junction Organization Regulation Of Actin Filament-based Process Regulation Of Cellular Component Movement Ventricular Cardiac Muscle Tissue Morphogenesis Response To Progesterone Ventricular Cardiac Muscle Tissue Development Cellular Component Assembly Cardiac Muscle Tissue Morphogenesis Apoptotic Process Programmed Cell Death Muscle Tissue Morphogenesis Cell Death Death Muscle Organ Morphogenesis Cardiac Ventricle Morphogenesis Cytoskeleton Organization Establishment Of Protein Localization To Plasma Membrane Maternal Process Involved In Female Pregnancy Cardiac Ventricle Development Ventricular Compact Myocardium Morphogenesis Endothelial Cell-cell Adhesion Adherens Junction Maintenance Cardiac Chamber Development	Bundle Of His Cell To Purkinje Myocyte Communication Ventricular Cardiac Muscle Cell Action Potential Regulation Of Heart Rate By Cardiac Conduction Cardiac Muscle Cell Action Potential Involved In Contraction Cardiac Muscle Cell Action Potential Regulation Of Cardiac Muscle Cell Contraction Cardiac Conduction Homophilic Cell Adhesion Via Plasma Membrane Adhesion Molecules Regulation Of Heart Rate Regulation Of Cardiac Muscle Contraction Regulation Of Striated Muscle Contraction Action Potential Cell-cell Adhesion Via Plasma-membrane Adhesion Molecules Cell-cell Adhesion Cell Adhesion Regulation Of Muscle Contraction Regulation Of Heart Contraction Cellular Component Disassembly Involved In Execution Phase Of Apoptosis Execution Phase Of Apoptosis Regulation Of Membrane Potential Cardiac Muscle Cell-cardiac Muscle Cell Adhesion Regulation Of Actin Filament-based Process Single Organismal Cell-cell Adhesion Regulation Of Cellular Component Movement Desmosome Organization Apoptotic Process Programmed Cell Death Cell Death Death Cell-cell Junction Organization Intermediate Filament Cytoskeleton Organization Intermediate Filament-based Process Response To Progesterone Golgi To Plasma Membrane CFTR Protein Transport Establishment Of Protein Localization To Plasma Membrane Maternal Process Involved In Female Pregnancy Adherens Junction Organization Protein Stabilization Ventricular Compact Myocardium Morphogenesis Cell-cell Junction Assembly Signaling Cell Communication Endothelial Cell-cell Adhesion Regulation Of Protein Stability Cellular Response To Starvation Response To Stimulus Protein Localization To Plasma Membrane Desmosome Assembly Protein Localization To Adherens Junction Cellular Response To Indole-3-methanol
Tagcloud ?		cadherins companion continuity desmocollin desmoglein desmoplakin desmosomal desmosomes displaying dsc2 dsc3 dsg1 dsg2 dsg3 exclusive follicle hair immunopositive mutually ontogenic outer plakoglobin plakophilin practically rood root sheath subinfundibular trichocytes	ankrd33b asthma beadchip cntd2 concordant cpg detrimental dpp10 enrichment epigenome fetal goal gtf2h2c gtf2h2d humanmethylation450 illumina ius lung mapped methylation methylome nicotine origins placental smoke surrogate utero variation wheezing
Tagcloud (Difference) ?		cadherins companion continuity desmocollin desmoglein desmoplakin desmosomal desmosomes displaying dsc2 dsc3 dsg1 dsg2 dsg3 exclusive follicle hair immunopositive mutually ontogenic outer plakoglobin plakophilin practically rood root sheath subinfundibular trichocytes	ankrd33b asthma beadchip cntd2 concordant cpg detrimental dpp10 enrichment epigenome fetal goal gtf2h2c gtf2h2d humanmethylation450 illumina ius lung mapped methylation methylome nicotine origins placental smoke surrogate utero variation wheezing
Tagcloud (Intersection) ?