DMPK and GEMIN4

Number of citations of the paper that reports this interaction (PMID 21988832)
14

Data Source:
BioGRID (two hybrid)

		DMPK	GEMIN4
Gene Name		dystrophia myotonica-protein kinase	gem (nuclear organelle) associated protein 4
Image			No pdb structure
Gene Ontology Annotations	Cellular Component	Nuclear Outer Membrane Endoplasmic Reticulum Membrane Cytosol Plasma Membrane Integral Component Of Mitochondrial Outer Membrane Nuclear Membrane Sarcoplasmic Reticulum Membrane	Nucleoplasm Nucleolus Cytoplasm Cytosol Membrane Small Nuclear Ribonucleoprotein Complex SMN Complex SMN-Sm Protein Complex Extracellular Vesicular Exosome Gemini Of Coiled Bodies
	Molecular Function	Protein Serine/threonine Kinase Activity Protein Binding ATP Binding Myosin Phosphatase Regulator Activity Metal Ion Binding	Protein Binding
	Biological Process	Protein Phosphorylation Cellular Calcium Ion Homeostasis Nuclear Envelope Organization Regulation Of Heart Contraction Muscle Cell Apoptotic Process Regulation Of Myotube Differentiation Regulation Of Catalytic Activity	Spliceosomal SnRNP Assembly RRNA Processing Gene Expression NcRNA Metabolic Process
Pathways			snRNP Assembly Metabolism of non-coding RNA
Drugs
Diseases
GWAS			Prostate cancer ( 23535732)
Protein-Protein Interactions		18 interactors: ANXA7 ATN1 ATXN1 CELF1 FXYD1 GABARAP GEMIN4 HOXA2 HSPB2 PIN1 PLN PPP1R12A RAC1 RAF1 RPS10 SMN1 TK1 UBQLN4	25 interactors: AGO2 CALCOCO2 DDX20 DHX9 DMPK FLAD1 GEMIN5 GLYR1 KARS LGALS1 LGALS3 MORC4 PIAS3 RN7SL1 RNU1-1 RNU2-1 SNRPB SNRPD1 SNRPD2 SPRY1 SQSTM1 SRRT STXBP2 STXBP3 TOP1
Entrez ID		1760	50628
HPRD ID		05645	07370
Ensembl ID		ENSG00000104936	ENSG00000179409
Uniprot IDs		E5KR05 E5KR06 E5KR07 E5KR08 M0R333 Q09013	I3L2C7 P57678 Q8WUM5
PDB IDs		1WT6 2VD5
Enriched GO Terms of Interacting Partners?		Regulation Of Cardiac Muscle Cell Membrane Potential Cellular Component Assembly Response To Organic Substance Ribonucleoprotein Complex Assembly Spliceosomal SnRNP Assembly MRNA Metabolic Process MRNA Splicing, Via Spliceosome RNA Splicing, Via Transesterification Reactions RNA Processing Death-inducing Signaling Complex Assembly Fetal Process Involved In Parturition Negative Regulation Of Calcium Ion Import Into Sarcoplasmic Reticulum Negative Regulation Of Calcium-transporting ATPase Activity Spliceosomal Complex Assembly Anatomical Structure Development Regulation Of Membrane Potential Cellular Macromolecular Complex Assembly Cellular Calcium Ion Homeostasis Calcium Ion Homeostasis Regulation Of Cellular Component Movement Embryonic Olfactory Bulb Interneuron Precursor Migration Negative Regulation Of Interleukin-23 Production Rhombomere 3 Morphogenesis Rhombomere 2 Development Skeletal Muscle Cell Proliferation Negative Regulation Of Calcium Ion Binding Regulation Of The Force Of Heart Contraction By Cardiac Conduction Ribonucleoprotein Complex Biogenesis Response To Metal Ion Cell Proliferation Regulation Of Rho Protein Signal Transduction RNA Splicing Response To Osmotic Stress Apoptotic Signaling Pathway Regulation Of Metabolic Process Brain Segmentation Engulfment Of Apoptotic Cell Regulation Of Myosin-light-chain-phosphatase Activity Regulation Of Calcium-transporting ATPase Activity Adrenergic Receptor Signaling Pathway Involved In Heart Process Negative Regulation Of Gene Expression Vascular Endothelial Growth Factor Receptor Signaling Pathway Developmental Process Axon Guidance Extrinsic Apoptotic Signaling Pathway Mast Cell Chemotaxis Rhombomere 3 Development Positive Regulation Of Sodium Ion Export From Cell G-protein Coupled Receptor Signaling Pathway Involved In Heart Process Negative Regulation Of Cellular Metabolic Process	Spliceosomal SnRNP Assembly RNA Processing MRNA Processing NcRNA Metabolic Process Ribonucleoprotein Complex Assembly MRNA Metabolic Process RNA Splicing MRNA Splicing, Via Spliceosome RNA Splicing, Via Transesterification Reactions Ribonucleoprotein Complex Biogenesis Nucleobase-containing Compound Metabolic Process Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Cellular Nitrogen Compound Metabolic Process Cellular Macromolecular Complex Assembly Neutrophil Degranulation RNA Metabolic Process Nitrogen Compound Metabolic Process Neutrophil Activation Involved In Immune Response Gene Expression Immune Response Cellular Component Assembly Neutrophil Mediated Immunity Production Of MiRNAs Involved In Gene Silencing By MiRNA Neutrophil Activation Immune System Process Leukocyte Activation Involved In Immune Response Gene Silencing By MiRNA Cellular Response To DsRNA Posttranscriptional Gene Silencing Leukocyte Degranulation Lysyl-tRNA Aminoacylation Negative Regulation Of Immunological Synapse Formation FAD Biosynthetic Process Positive Regulation Of Erythrocyte Aggregation Regulated Secretory Pathway Vesicle Docking Involved In Exocytosis Spliceosomal Complex Assembly Gene Silencing By RNA Cellular Metabolic Process MRNA Cleavage Involved In Gene Silencing By MiRNA Negative Regulation Of T Cell Activation Via T Cell Receptor Contact With Antigen Bound To MHC Molecule On Antigen Presenting Cell Diadenosine Tetraphosphate Biosynthetic Process Response To DsRNA Cellular Process Vesicle Docking Membrane Docking SiRNA Loading Onto RISC Involved In RNA Interference Positive Regulation Of Mononuclear Cell Migration Mononuclear Cell Migration
Tagcloud ?		acquire arenas bioanalysis budgets capturing career celltech ei employing exactive graduating introducing joined lloyd momentum oceanography orbitrap pharma projects qc qual quan spent swansea tasked thermospray ucb whilst wyeth	a1 a11 a2 a4 a5 a6 accomplishments annealing annexin annexins carbohydrate conjunction cytoplasm cytoskeleton extensively galectin galectins helicase inside interacting lectin lectins outside phospholipid possesses primer summarizes synexin unwinding
Tagcloud (Difference) ?		acquire arenas bioanalysis budgets capturing career celltech ei employing exactive graduating introducing joined lloyd momentum oceanography orbitrap pharma projects qc qual quan spent swansea tasked thermospray ucb whilst wyeth	a1 a11 a2 a4 a5 a6 accomplishments annealing annexin annexins carbohydrate conjunction cytoplasm cytoskeleton extensively galectin galectins helicase inside interacting lectin lectins outside phospholipid possesses primer summarizes synexin unwinding
Tagcloud (Intersection) ?