SMYD1 and OGDHL

Number of citations of the paper that reports this interaction (PMID 23455924)
3

Data Source:
BioGRID (two hybrid)

		SMYD1	OGDHL
Gene Name		SET and MYND domain containing 1	oxoglutarate dehydrogenase-like
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleus Cytoplasm	Mitochondrion Mitochondrial Matrix Cytosol Oxoglutarate Dehydrogenase Complex
	Molecular Function	DNA Binding Transcription Corepressor Activity Protein Binding Histone-lysine N-methyltransferase Activity Metal Ion Binding	Oxoglutarate Dehydrogenase (succinyl-transferring) Activity Protein Binding Thiamine Pyrophosphate Binding Metal Ion Binding
	Biological Process	Chromatin Remodeling Transcription, DNA-templated Heart Development Positive Regulation Of Myotube Differentiation Histone Lysine Methylation Skeletal Muscle Cell Differentiation Positive Regulation Of Myoblast Differentiation Negative Regulation Of Transcription, DNA-templated	Glycolytic Process Tricarboxylic Acid Cycle
Pathways
Drugs
Diseases
GWAS
Protein-Protein Interactions		19 interactors: ADSS BHLHE40 C11orf16 C11orf53 CCDC113 FAM204A H3F3C HDAC2 HDAC3 HOMEZ LENG8 MYH7B NACA OGDHL RBM4B TTC33 UTP14A WDR77 ZBTB44	2 interactors: SMYD1 STAT3
Entrez ID		150572	55753
HPRD ID		06025	07704
Ensembl ID		ENSG00000115593	ENSG00000197444
Uniprot IDs		E9PHG3 Q5HYE8 Q8NB12	Q9ULD0
PDB IDs
Enriched GO Terms of Interacting Partners?		Circadian Regulation Of Gene Expression Circadian Rhythm RNA Metabolic Process Rhythmic Process Nucleobase-containing Compound Metabolic Process Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Histone H4 Deacetylation Negative Regulation Of Transcription From RNA Polymerase II Promoter Cellular Nitrogen Compound Metabolic Process Entrainment Of Circadian Clock By Photoperiod Photoperiodism Entrainment Of Circadian Clock Histone H3 Deacetylation Nitrogen Compound Metabolic Process Histone H3-K9 Modification Gene Expression Negative Regulation Of Transcription, DNA-templated Negative Regulation Of Nucleic Acid-templated Transcription Negative Regulation Of RNA Biosynthetic Process Regulation Of Growth Regulation Of Transcription From RNA Polymerase II Promoter Histone Deacetylation Regulation Of Developmental Growth Protein Deacetylation Negative Regulation Of Transcription From RNA Polymerase II Promoter Involved In Heart Development Negative Regulation Of Gene Expression Negative Regulation Of Biosynthetic Process Transcription, DNA-templated Response To Ammonium Ion Regulation Of Striated Muscle Cell Differentiation RNA Biosynthetic Process Regulation Of Circadian Rhythm Maintenance Of Chromatin Silencing 'de Novo' AMP Biosynthetic Process Positive Regulation Of Skeletal Muscle Tissue Growth Negative Regulation Of Sequence-specific DNA Binding Transcription Factor Activity Secretory Columnal Luminar Epithelial Cell Differentiation Involved In Prostate Glandular Acinus Development Regulation Of Striated Muscle Tissue Development Regulation Of Gene Expression Response To Abiotic Stimulus Positive Regulation Of Transcription From RNA Polymerase II Promoter Involved In Heart Development AMP Biosynthetic Process Negative Regulation Of MHC Class II Biosynthetic Process Regulation Of Muscle Cell Differentiation Aspartate Metabolic Process Fungiform Papilla Formation Negative Regulation Of Cardiac Muscle Cell Proliferation Negative Regulation Of Cellular Metabolic Process Fungiform Papilla Morphogenesis	Negative Regulation Of Glycolytic Process Radial Glial Cell Differentiation Interleukin-6-mediated Signaling Pathway Positive Regulation Of Myoblast Differentiation JAK-STAT Cascade Involved In Growth Hormone Signaling Pathway Temperature Homeostasis Growth Hormone Receptor Signaling Pathway Regulation Of Glycolytic Process Cellular Response To Growth Hormone Stimulus Cellular Response To Interleukin-6 Negative Regulation Of Transcription, DNA-templated Positive Regulation Of Notch Signaling Pathway Negative Regulation Of Nucleic Acid-templated Transcription Negative Regulation Of RNA Biosynthetic Process Eating Behavior Negative Regulation Of Neuron Migration Response To Interleukin-6 Positive Regulation Of Myotube Differentiation Negative Regulation Of Gene Expression Acute-phase Response Response To Growth Hormone Negative Regulation Of Biosynthetic Process Astrocyte Differentiation Regulation Of Myoblast Differentiation Eye Photoreceptor Cell Differentiation JAK-STAT Cascade Regulation Of Cell Differentiation Regulation Of Neuron Migration Regulation Of Myotube Differentiation Skeletal Muscle Cell Differentiation Positive Regulation Of Striated Muscle Cell Differentiation Regulation Of Notch Signaling Pathway Somatic Stem Cell Maintenance Regulation Of Generation Of Precursor Metabolites And Energy Acute Inflammatory Response Positive Regulation Of Muscle Cell Differentiation Histone Lysine Methylation Negative Regulation Of Cellular Metabolic Process Peptidyl-lysine Methylation Feeding Behavior Regulation Of Striated Muscle Cell Differentiation Regulation Of Multicellular Organism Growth Transcription, DNA-templated Protein Import Into Nucleus Response To Estradiol Histone Methylation RNA Biosynthetic Process Nuclear Import Skeletal Muscle Tissue Development Response To Ethanol
Tagcloud ?		adenosylhomocysteine autoinhibited autoinhibition away bend bending cochaperones crevice ctd ctds flexibility helices interdomain intradomain k4 lobed methylate move outwards restricts sinefungin smyd2 smyd3 stabilizes structurally superimposable tetratricopeptide tpr
Tagcloud (Difference) ?		adenosylhomocysteine autoinhibited autoinhibition away bend bending cochaperones crevice ctd ctds flexibility helices interdomain intradomain k4 lobed methylate move outwards restricts sinefungin smyd2 smyd3 stabilizes structurally superimposable tetratricopeptide tpr
Tagcloud (Intersection) ?