CRYAA and CRYGD

Number of citations of the paper that reports this interaction (PMID 22655036)
6

Data Source:
BioGRID (pull down)

		CRYAA	CRYGD
Gene Name		crystallin, alpha A	crystallin, gamma D
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleus Cytoplasm Extracellular Vesicular Exosome	Nucleus Cytoplasm
	Molecular Function	Structural Constituent Of Eye Lens Protein Binding Identical Protein Binding Metal Ion Binding Unfolded Protein Binding	Structural Constituent Of Eye Lens Protein Binding
	Biological Process	Visual Perception Negative Regulation Of Intracellular Transport Protein Refolding Negative Regulation Of Apoptotic Process Response To Stimulus Protein Homooligomerization	Lens Development In Camera-type Eye Visual Perception Cellular Response To Reactive Oxygen Species Lens Fiber Cell Differentiation
Pathways
Drugs
Diseases
GWAS
Protein-Protein Interactions		17 interactors: ALB BCL2L1 CRYAB CRYBA1 CRYBB2 CRYGC CRYGD CRYZ CS GORASP2 HSPB1 HSPB2 LALBA MIP SDCBP SPG21 WDYHV1	3 interactors: CRYAA CRYAB CRYGC
Entrez ID		1409	1421
HPRD ID		00427	00436
Ensembl ID		ENSG00000160202	ENSG00000118231
Uniprot IDs		E9PHE4 P02489	P07320
PDB IDs			1H4A 1HK0 1LD0 2G98 2KFB 2KLJ 4GR7 4JGF
Enriched GO Terms of Interacting Partners?		Visual Perception Sensory Perception Of Light Stimulus Camera-type Eye Development Eye Development Lens Development In Camera-type Eye Sensory Organ Development Sensory Perception Cellular Response To Gamma Radiation Neurological System Process Bile Acid And Bile Salt Transport Response To Gamma Radiation Cellular Response To Ionizing Radiation Apoptotic Process In Bone Marrow Retina Homeostasis Maintenance Of Mitochondrion Location Lactose Biosynthetic Process Response To Platinum Ion Hemolysis By Symbiont Of Host Erythrocytes Positive Regulation Of Circadian Sleep/wake Cycle, Non-REM Sleep Negative Regulation Of Intrinsic Apoptotic Signaling Pathway Response To Stimulus Interaction With Host Organ Development Positive Regulation Of Extracellular Vesicular Exosome Assembly Positive Regulation Of Endothelial Cell Chemotaxis By VEGF-activated Vascular Endothelial Growth Factor Receptor Signaling Pathway Suppression By Virus Of Host Apoptotic Process Anatomical Structure Development Negative Regulation Of Apoptotic Process Negative Regulation Of Programmed Cell Death Positive Regulation Of Cell Migration By Vascular Endothelial Growth Factor Signaling Pathway Disaccharide Metabolic Process Canalicular Bile Acid Transport Positive Regulation Of Behavior Monocarboxylic Acid Transport Response To Unfolded Protein Regulation Of Extracellular Vesicular Exosome Assembly Negative Regulation Of Cell Death Cellular Response To Radiation System Development Response To Ionizing Radiation Protein Processing Involved In Protein Targeting To Mitochondrion Response To Cycloheximide Cellular Process Regulating Host Cell Cycle In Response To Virus Mitochondrial Transport Regulation Of Intrinsic Apoptotic Signaling Pathway Tubulin Complex Assembly Positive Regulation Of Endothelial Cell Chemotaxis Negative Regulation Of Execution Phase Of Apoptosis Regulation Of Circadian Sleep/wake Cycle, Non-REM Sleep Response To Stress	Negative Regulation Of Intracellular Transport Visual Perception Sensory Perception Of Light Stimulus Protein Homooligomerization Camera-type Eye Development Negative Regulation Of Transport Eye Development Tubulin Complex Assembly Protein Oligomerization Regulation Of Intracellular Transport Sensory Organ Development Apoptotic Process Involved In Morphogenesis Cellular Response To Gamma Radiation Apoptotic Process Involved In Development Sensory Perception Negative Regulation Of Apoptotic Process Developmental Programmed Cell Death Negative Regulation Of Programmed Cell Death Microtubule Polymerization Or Depolymerization Negative Regulation Of Cell Death Negative Regulation Of Reactive Oxygen Species Metabolic Process Protein Complex Assembly Regulation Of Cellular Localization Response To Gamma Radiation Neurological System Process Cellular Response To Ionizing Radiation Negative Regulation Of Cysteine-type Endopeptidase Activity Involved In Apoptotic Process Negative Regulation Of Cysteine-type Endopeptidase Activity Regulation Of Apoptotic Process Lens Development In Camera-type Eye Regulation Of Cell Death Stress-activated MAPK Cascade Stress-activated Protein Kinase Signaling Cascade Response To Estradiol Response To Hydrogen Peroxide
Tagcloud ?		aiims beaded bfsp1 cataract congenital cryab cryba1 cryba4 crybb1 crybb2 crybb3 crygs crystallin cx d85n delhi e155k e75k expands filament fourteen gja3 gja8 m1v ophthalmic sciences studio transparency y67n	2j 6v2 beadchip bxd crosses cryab cryba1 crybb3 cryga crystallin crystallins dba extralenticular genenetwork genomatix hamilton hei hle hlec illumina immunoblots inbred maf mafa mousewg retina rgc ri sentrix
Tagcloud (Difference) ?		aiims beaded bfsp1 cataract congenital cryba4 crybb1 crybb2 crygs cx d85n delhi e155k e75k expands filament fourteen gja3 gja8 m1v ophthalmic sciences studio transparency y67n	2j 6v2 beadchip bxd crosses cryga crystallins dba extralenticular genenetwork genomatix hamilton hei hle hlec illumina immunoblots inbred maf mafa mousewg retina rgc ri sentrix
Tagcloud (Intersection) ?		cryab cryba1 crybb3 crystallin