CRYAA and CRYBA1

Number of citations of the paper that reports this interaction (PMID 19401464)
3

Data Source:
BioGRID (pull down, imaging technique, two hybrid, fluorescent resonance energy transfer)

		CRYAA	CRYBA1
Gene Name		crystallin, alpha A	crystallin, beta A1
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleus Cytoplasm Extracellular Vesicular Exosome	Nucleus Cytoplasm
	Molecular Function	Structural Constituent Of Eye Lens Protein Binding Identical Protein Binding Metal Ion Binding Unfolded Protein Binding	Molecular_function Structural Constituent Of Eye Lens Protein Binding Protein Homodimerization Activity
	Biological Process	Visual Perception Negative Regulation Of Intracellular Transport Protein Refolding Negative Regulation Of Apoptotic Process Response To Stimulus Protein Homooligomerization	Lens Development In Camera-type Eye Visual Perception
Pathways
Drugs
Diseases
GWAS
Protein-Protein Interactions		17 interactors: ALB BCL2L1 CRYAB CRYBA1 CRYBB2 CRYGC CRYGD CRYZ CS GORASP2 HSPB1 HSPB2 LALBA MIP SDCBP SPG21 WDYHV1	7 interactors: CRYAA CRYAB CRYBB1 CRYBB2 CRYBB3 RBPMS RHOXF2
Entrez ID		1409	1411
HPRD ID		00427	00429
Ensembl ID		ENSG00000160202	ENSG00000108255
Uniprot IDs		E9PHE4 P02489	P05813
PDB IDs
Enriched GO Terms of Interacting Partners?		Visual Perception Sensory Perception Of Light Stimulus Camera-type Eye Development Eye Development Lens Development In Camera-type Eye Sensory Organ Development Sensory Perception Cellular Response To Gamma Radiation Neurological System Process Bile Acid And Bile Salt Transport Response To Gamma Radiation Cellular Response To Ionizing Radiation Apoptotic Process In Bone Marrow Retina Homeostasis Maintenance Of Mitochondrion Location Lactose Biosynthetic Process Response To Platinum Ion Hemolysis By Symbiont Of Host Erythrocytes Positive Regulation Of Circadian Sleep/wake Cycle, Non-REM Sleep Negative Regulation Of Intrinsic Apoptotic Signaling Pathway Response To Stimulus Interaction With Host Organ Development Positive Regulation Of Extracellular Vesicular Exosome Assembly Positive Regulation Of Endothelial Cell Chemotaxis By VEGF-activated Vascular Endothelial Growth Factor Receptor Signaling Pathway Suppression By Virus Of Host Apoptotic Process Anatomical Structure Development Negative Regulation Of Apoptotic Process Negative Regulation Of Programmed Cell Death Positive Regulation Of Cell Migration By Vascular Endothelial Growth Factor Signaling Pathway Disaccharide Metabolic Process Canalicular Bile Acid Transport Positive Regulation Of Behavior Monocarboxylic Acid Transport Response To Unfolded Protein Regulation Of Extracellular Vesicular Exosome Assembly Negative Regulation Of Cell Death Cellular Response To Radiation System Development Response To Ionizing Radiation Protein Processing Involved In Protein Targeting To Mitochondrion Response To Cycloheximide Cellular Process Regulating Host Cell Cycle In Response To Virus Mitochondrial Transport Regulation Of Intrinsic Apoptotic Signaling Pathway Tubulin Complex Assembly Positive Regulation Of Endothelial Cell Chemotaxis Negative Regulation Of Execution Phase Of Apoptosis Regulation Of Circadian Sleep/wake Cycle, Non-REM Sleep Response To Stress	Visual Perception Sensory Perception Of Light Stimulus Sensory Perception Neurological System Process Regulation Of Intracellular Transport Negative Regulation Of Intracellular Transport Tubulin Complex Assembly Protein Homooligomerization Regulation Of Cellular Localization
Tagcloud ?		aiims beaded bfsp1 cataract congenital cryab cryba1 cryba4 crybb1 crybb2 crybb3 crygs crystallin cx d85n delhi e155k e75k expands filament fourteen gja3 gja8 m1v ophthalmic sciences studio transparency y67n	17q11 assayed base betaa3 betaa3a1 bits blindness cataracts causally cczs cosegregates creates crystallin digestion intron lowers mapped morphologically mutational nlaiii opacities q12 sequenced splice splicing sutural tgagt zonular
Tagcloud (Difference) ?		aiims beaded bfsp1 cataract congenital cryab cryba4 crybb1 crybb2 crybb3 crygs cx d85n delhi e155k e75k expands filament fourteen gja3 gja8 m1v ophthalmic sciences studio transparency y67n	17q11 assayed base betaa3 betaa3a1 bits blindness cataracts causally cczs cosegregates creates digestion intron lowers mapped morphologically mutational nlaiii opacities q12 sequenced splice splicing sutural tgagt zonular
Tagcloud (Intersection) ?		cryba1 crystallin