NACC2 and MTA3

Number of citations of the paper that reports this interaction (PMID 22926524)
0

Data Source:
BioGRID (pull down)

		NACC2	MTA3
Gene Name		NACC family member 2, BEN and BTB (POZ) domain containing	metastasis associated 1 family, member 3
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Nuclear Chromatin Nucleus NuRD Complex Nuclear Body	Nucleus Nucleoplasm Intracellular Membrane-bounded Organelle
	Molecular Function	RNA Polymerase II Core Promoter Proximal Region Sequence-specific DNA Binding RNA Polymerase II Transcription Factor Binding Transcription Factor Activity RNA Polymerase II Core Promoter Proximal Region Sequence-specific DNA Binding Transcription Factor Activity Involved In Negative Regulation Of Transcription Histone Deacetylase Activity Protein Binding Protein Homodimerization Activity Histone Deacetylase Binding	Chromatin Binding Sequence-specific DNA Binding Transcription Factor Activity Protein Binding Zinc Ion Binding Sequence-specific DNA Binding
	Biological Process	Transcription From RNA Polymerase II Promoter Positive Regulation Of Cell Proliferation Negative Regulation Of Cell Proliferation Posttranscriptional Regulation Of Gene Expression Histone Deacetylation Cellular Protein Complex Localization Negative Regulation Of Transcription, DNA-templated Protein Homooligomerization Negative Regulation Of G1/S Transition Of Mitotic Cell Cycle By Negative Regulation Of Transcription From RNA Polymerase II Promoter Positive Regulation Of Intrinsic Apoptotic Signaling Pathway In Response To DNA Damage	Chromatin Organization Regulation Of Transcription, DNA-templated
Pathways			Chromatin modifying enzymes Chromatin organization HDACs deacetylate histones RNA Polymerase I, RNA Polymerase III, and Mitochondrial Transcription RNA Polymerase I Transcription RNA Polymerase I Transcription Initiation RNA Polymerase I Promoter Clearance
Drugs
Diseases
GWAS
Protein-Protein Interactions		5 interactors: EPS8 HDAC2 MTA1 MTA2 MTA3	6 interactors: ARNT BCL6 ESR1 GRB2 KDM1A NACC2
Entrez ID		138151	57504
HPRD ID		09831	12359
Ensembl ID		ENSG00000148411	ENSG00000057935
Uniprot IDs		Q96BF6	E7EQY4 Q9BTC8
PDB IDs
Enriched GO Terms of Interacting Partners?		Chromatin Organization Regulation Of Gene Expression, Epigenetic Chromosome Organization Organelle Organization Histone Deacetylation Protein Deacetylation ATP-dependent Chromatin Remodeling Circadian Regulation Of Gene Expression Positive Regulation Of Protein Autoubiquitination Circadian Rhythm Chromatin Remodeling Regulation Of Protein Autoubiquitination Maintenance Of Chromatin Silencing Actin Polymerization-dependent Cell Motility Locomotory Behavior Negative Regulation Of Nucleic Acid-templated Transcription Negative Regulation Of RNA Biosynthetic Process Negative Regulation Of MHC Class II Biosynthetic Process Exit From Mitosis Fungiform Papilla Formation Negative Regulation Of Cardiac Muscle Cell Proliferation Rhythmic Process Negative Regulation Of Biosynthetic Process Fungiform Papilla Morphogenesis Behavioral Response To Ethanol Locomotor Rhythm Positive Regulation Of Receptor Biosynthetic Process Regulation Of Actin Cytoskeleton Organization Fungiform Papilla Development Regulation Of Sarcomere Organization Eyelid Development In Camera-type Eye Histone Modification Regulation Of Actin Filament-based Process Hair Follicle Placode Formation Positive Regulation Of Oligodendrocyte Differentiation Tongue Morphogenesis Negative Regulation Of Cardiac Muscle Tissue Development Single-organism Behavior Rac Protein Signal Transduction Regulation Of Receptor Biosynthetic Process Circadian Behavior Histone H4 Deacetylation Rhythmic Behavior Regulation Of Cytoskeleton Organization Barbed-end Actin Filament Capping Actin Crosslink Formation Dendritic Cell Migration Regulation Of Transcription, DNA-templated Entrainment Of Circadian Clock By Photoperiod Regulation Of Nucleic Acid-templated Transcription	Positive Regulation Of Cell Proliferation Regulation Of Signal Transduction Positive Regulation Of Hormone Biosynthetic Process Regulation Of Signaling Regulation Of Cell Proliferation Positive Regulation Of Erythrocyte Differentiation Regulation Of Intracellular Signal Transduction Regulation Of Transcription From RNA Polymerase II Promoter Regulation Of Hormone Biosynthetic Process Transcription From RNA Polymerase II Promoter Positive Regulation Of Immune System Process Regulation Of Hormone Metabolic Process Regulation Of Erythrocyte Differentiation Transcription, DNA-templated RNA Biosynthetic Process Negative Regulation Of Signal Transduction Positive Regulation Of Cellular Metabolic Process Negative Regulation Of Signaling Single Organism Reproductive Process Negative Regulation Of Intracellular Signal Transduction Positive Regulation Of Signal Transduction Regulation Of Immune System Process Reproductive Process Negative Regulation Of Gene Expression Positive Regulation Of Myeloid Cell Differentiation Reproductive Structure Development Organ Development Reproductive System Development In Utero Embryonic Development Regulation Of Apoptotic Process Positive Regulation Of Reactive Oxygen Species Metabolic Process Regulation Of Cell Death RNA Metabolic Process Negative Regulation Of G1/S Transition Of Mitotic Cell Cycle By Negative Regulation Of Transcription From RNA Polymerase II Promoter Regulation Of Primitive Erythrocyte Differentiation Chromatin Modification Cell Differentiation Positive Regulation Of Metabolic Process Gene Expression Embryonic Placenta Development Negative Regulation Of Sequence-specific DNA Binding Transcription Factor Activity Regulation Of Histone Modification Regulation Of Response To DNA Damage Stimulus Cellular Macromolecule Biosynthetic Process Cell Development Macromolecule Biosynthetic Process Chromatin Organization Developmental Process Involved In Reproduction Regulation Of Reactive Oxygen Species Metabolic Process Regulation Of Intrinsic Apoptotic Signaling Pathway
Tagcloud ?			adds aggressive axis claudin clinicopathological cohorts depicted determining dfs diminished diminution discovered downregulated drives ductal emt lowest mesenchymal operable partly progesterone raf registered rkip shorter sized snail subtype subtyping
Tagcloud (Difference) ?			adds aggressive axis claudin clinicopathological cohorts depicted determining dfs diminished diminution discovered downregulated drives ductal emt lowest mesenchymal operable partly progesterone raf registered rkip shorter sized snail subtype subtyping
Tagcloud (Intersection) ?