CPN1 and CLEC4G

Number of citations of the paper that reports this interaction (PMID 18624398)
4

Data Source:
BioGRID (two hybrid)

		CPN1	CLEC4G
Gene Name		carboxypeptidase N, polypeptide 1	C-type lectin domain family 4, member G
Image			No pdb structure
Gene Ontology Annotations	Cellular Component	Extracellular Space	Integral Component Of Membrane
	Molecular Function	Metallocarboxypeptidase Activity Zinc Ion Binding	Protein Binding Carbohydrate Binding
	Biological Process	Proteolysis Bradykinin Catabolic Process Response To Glucocorticoid
Pathways		Peptide hormone metabolism Insulin processing
Drugs
Diseases
GWAS		Bone mineral density ( 22504420) Height ( 20881960) Liver enzyme levels ( 18940312) Liver enzyme levels (alanine transaminase) ( 22001757)
Protein-Protein Interactions		6 interactors: C3 C5 CDC42 CLEC4G CPN2 KNG1	19 interactors: APOA1 APOH ARSA ASGR1 AZU1 CAPN1 COX1 CPN1 EIF6 FTL GEM IFI35 MAP3K11 NUP214 PKLR PRDX1 RPSA SHBG WBP2
Entrez ID		1369	339390
HPRD ID		09120	16721
Ensembl ID		ENSG00000120054	ENSG00000182566
Uniprot IDs		B1AP59 P15169	B7ZKQ2 Q08G24 Q6UXB4 Q6XYD1
PDB IDs		2NSM
Enriched GO Terms of Interacting Partners?		Complement Activation, Alternative Pathway Protein Activation Cascade Positive Regulation Of Transport Regulation Of Catalytic Activity Negative Regulation Of Endopeptidase Activity Negative Regulation Of Peptidase Activity Regulation Of Complement Activation Positive Regulation Vascular Endothelial Growth Factor Production Negative Regulation Of Proteolysis Negative Regulation Of Protein Processing Regulation Of Vascular Endothelial Growth Factor Production Regulation Of Endopeptidase Activity Regulation Of Humoral Immune Response Negative Regulation Of Hydrolase Activity Regulation Of Protein Processing Defense Response Regulation Of Peptidase Activity Inflammatory Response Regulation Of Acute Inflammatory Response Positive Regulation Of Immune Response Regulation Of Proteolysis Regulation Of Cellular Protein Metabolic Process Positive Regulation Of Protein Phosphorylation Positive Regulation Of Angiogenesis Complement Activation, Classical Pathway Regulation Of Protein Stability Humoral Immune Response Mediated By Circulating Immunoglobulin Regulation Of Protein Metabolic Process Negative Regulation Of Catalytic Activity Complement Activation Innate Immune Response Negative Regulation Of Cellular Protein Metabolic Process Negative Regulation Of Macrophage Chemotaxis Positive Regulation Of Hair Follicle Cell Proliferation Positive Regulation Of Type IIa Hypersensitivity Positive Regulation Of Phosphorylation Regulation Of Immune Response Negative Regulation Of Protein Metabolic Process Positive Regulation Of Immune System Process Positive Regulation Of Protein Modification Process Immunoglobulin Mediated Immune Response B Cell Mediated Immunity Actin Filament Branching Submandibular Salivary Gland Formation Regulation Of Hair Follicle Cell Proliferation Positive Regulation Of Synapse Structural Plasticity Positive Regulation Of Activation Of Membrane Attack Complex Regulation Of Protein Phosphorylation Regulation Of Angiogenesis Leukocyte Migration	Positive Regulation Of Lipoprotein Lipase Activity Nuclear Export Ribosome Assembly Response To Extracellular Stimulus Response To Steroid Hormone Response To Organic Cyclic Compound Response To Stimulus Response To Estrogen Response To Nutrient Response To Hormone Regulation Of Interleukin-1 Beta Production Positive Regulation Of Fractalkine Biosynthetic Process Positive Regulation Of Interleukin-1 Beta Biosynthetic Process Negative Regulation Of Cell Adhesion Molecule Production Primary Spermatocyte Growth Nucleocytoplasmic Transport Nuclear Transport RNA Export From Nucleus RRNA Export From Nucleus Endonucleolytic Cleavage To Generate Mature 3'-end Of SSU-rRNA From (SSU-rRNA, 5.8S RRNA, LSU-rRNA) Negative Regulation Of Interleukin-1 Beta Secretion Positive Regulation Of Histone H3-K14 Acetylation Cellular Localization Catabolic Process Response To Organic Substance Positive Regulation Of Lipase Activity Viral Transcription Negative Regulation Of Very-low-density Lipoprotein Particle Remodeling Cholesterol Import Regulation Of Histone H3-K14 Acetylation Triglyceride Transport Receptor-mediated Endocytosis Lipid Metabolic Process Response To Stress Endonucleolytic Cleavage In ITS1 To Separate SSU-rRNA From 5.8S RRNA And LSU-rRNA From Tricistronic RRNA Transcript (SSU-rRNA, 5.8S RRNA, LSU-rRNA) Negative Regulation Of Interleukin-1 Secretion Establishment Of Localization In Cell Cellular Process Response To Lipid Bradykinin Catabolic Process RRNA Transport Pyruvate Biosynthetic Process Membrane Organization Response To Nutrient Levels Mature Ribosome Assembly RRNA 3'-end Processing High-density Lipoprotein Particle Clearance Cellular Response To Stimulus RNA Transport Protein Oxidation
Tagcloud ?		accumulates bimolecular catalyses complementation copine crystallinum cytoskeleton fermenting halophyte imbalanced interacted ka1 links mccpn1 mcskd1 mcsnrk1 mesembryanthemum myristoylation phosphorylate physically relate salt skd1 snrk1 stkc sucrose ternary uba ubiquitination
Tagcloud (Difference) ?		accumulates bimolecular catalyses complementation copine crystallinum cytoskeleton fermenting halophyte imbalanced interacted ka1 links mccpn1 mcskd1 mcsnrk1 mesembryanthemum myristoylation phosphorylate physically relate salt skd1 snrk1 stkc sucrose ternary uba ubiquitination
Tagcloud (Intersection) ?