CORT and SSTR4

Number of citations of the paper that reports this interaction (PMID 9205124)
10

Data Source:
BioGRID (unspecified method)
HPRD (in vivo)

		CORT	SSTR4
Gene Name		cortistatin	somatostatin receptor 4
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Extracellular Space	Cytoplasm Plasma Membrane Integral Component Of Plasma Membrane Neuron Projection
	Molecular Function	G-protein Coupled Receptor Binding Neuropeptide Hormone Activity	Somatostatin Receptor Activity Neuropeptide Binding
	Biological Process	Adenylate Cyclase-inhibiting G-protein Coupled Receptor Signaling Pathway Synaptic Transmission	G-protein Coupled Receptor Signaling Pathway G-protein Coupled Receptor Signaling Pathway, Coupled To Cyclic Nucleotide Second Messenger Neuropeptide Signaling Pathway Synaptic Transmission Negative Regulation Of Cell Proliferation Cell Migration Arachidonic Acid Metabolic Process Negative Regulation Of CAMP Metabolic Process Forebrain Development Somatostatin Signaling Pathway Positive Regulation Of MAPK Cascade Cellular Response To Glucocorticoid Stimulus
Pathways			Defective ACTH causes Obesity and Pro-opiomelanocortinin deficiency (POMCD) Signaling by GPCR GPCR downstream signaling Peptide ligand-binding receptors Class A/1 (Rhodopsin-like receptors) G alpha (i) signalling events Metabolic disorders of biological oxidation enzymes GPCR ligand binding
Drugs
Diseases
GWAS			Obesity-related traits ( 23251661)
Protein-Protein Interactions		7 interactors: GHSR MRGPRX2 SSTR1 SSTR2 SSTR3 SSTR4 SSTR5	2 interactors: CORT SST
Entrez ID		1325	6754
HPRD ID		04150	01676
Ensembl ID		ENSG00000241563	ENSG00000132671
Uniprot IDs		O00230 Q8IUV6	P31391
PDB IDs
Enriched GO Terms of Interacting Partners?		Somatostatin Signaling Pathway Hormone-mediated Signaling Pathway Cellular Response To Estradiol Stimulus Neuropeptide Signaling Pathway Cellular Response To Peptide Hormone Stimulus Cellular Response To Peptide Cellular Response To Estrogen Stimulus G-protein Coupled Receptor Signaling Pathway, Coupled To Cyclic Nucleotide Second Messenger Response To Peptide Hormone Cellular Response To Organonitrogen Compound Cellular Response To Steroid Hormone Stimulus Response To Peptide G-protein Coupled Receptor Signaling Pathway Cellular Response To Glucocorticoid Stimulus Cellular Response To Corticosteroid Stimulus Cellular Response To Hormone Stimulus Response To Organonitrogen Compound Cell-cell Signaling Response To Estradiol Cellular Response To Organic Cyclic Compound Response To Hormone Cellular Response To Lipid Response To Glucocorticoid Response To Steroid Hormone Response To Corticosteroid Synaptic Transmission Response To Estrogen Negative Regulation Of Cell Proliferation Cell Surface Receptor Signaling Pathway Response To Lipid Response To Organic Cyclic Compound Cellular Response To Organic Substance Response To Nutrient Levels Cerebellum Development Forebrain Development Response To Extracellular Stimulus Metencephalon Development Response To Organic Substance Hindbrain Development Response To Starvation Regulation Of Cell Proliferation Regulation Of Insulin Secretion Regulation Of Peptide Hormone Secretion Signal Transduction Brain Development Head Development Multicellular Organismal Reproductive Process Regulation Of Hormone Secretion Signaling Multicellular Organism Reproduction	Hormone-mediated Apoptotic Signaling Pathway Synaptic Transmission Cell-cell Signaling Hyperosmotic Response G-protein Coupled Receptor Signaling Pathway Adenylate Cyclase-inhibiting G-protein Coupled Receptor Signaling Pathway
Tagcloud ?		b10 beta2 bioassays cleft clefts congenic corticosteroid dynamical dysmorphogenesis e14 fraser iir juriloff learn logic malformation outline palatal palate palates palatogenesis plasmin plasminogen proposes rules sequester slower tgf urokinase	arrays breast cohort component correlated correlation distribution epidermal estrogen evaluate hypothalamic independent interested luminal marker markers materials micro population principal produced sample somatostatin sstr2 subtype subtypes tma tumors
Tagcloud (Difference) ?		b10 beta2 bioassays cleft clefts congenic corticosteroid dynamical dysmorphogenesis e14 fraser iir juriloff learn logic malformation outline palatal palate palates palatogenesis plasmin plasminogen proposes rules sequester slower tgf urokinase	arrays breast cohort component correlated correlation distribution epidermal estrogen evaluate hypothalamic independent interested luminal marker markers materials micro population principal produced sample somatostatin sstr2 subtype subtypes tma tumors
Tagcloud (Intersection) ?