ACKR2 and CCL14

Number of citations of the paper that reports this interaction (PMID 9405404)
30

Data Source:
BioGRID (pull down)
HPRD (in vivo)

		ACKR2	CCL14
Gene Name		atypical chemokine receptor 2	chemokine (C-C motif) ligand 14
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Early Endosome Actin Filament Plasma Membrane Integral Component Of Plasma Membrane Recycling Endosome	Extracellular Space
	Molecular Function	Chemokine Receptor Activity Scavenger Receptor Activity C-C Chemokine Receptor Activity C-X-C Chemokine Receptor Activity C-C Chemokine Binding	Chemokine Activity
	Biological Process	Receptor-mediated Endocytosis Chemotaxis Inflammatory Response Immune Response G-protein Coupled Receptor Signaling Pathway Multicellular Organismal Development Neutrophil Activation Chemokine-mediated Signaling Pathway	Cellular Calcium Ion Homeostasis Immune Response Positive Regulation Of Cell Proliferation Cell Chemotaxis
Pathways		Defective ACTH causes Obesity and Pro-opiomelanocortinin deficiency (POMCD) Signaling by GPCR Peptide ligand-binding receptors Chemokine receptors bind chemokines Class A/1 (Rhodopsin-like receptors) Metabolic disorders of biological oxidation enzymes GPCR ligand binding
Drugs
Diseases
GWAS
Protein-Protein Interactions		16 interactors: APP CCL11 CCL13 CCL14 CCL19 CCL2 CCL21 CCL25 CCL27 CCL28 CCL3 CCL3L3 CCL4 CCL5 CCL7 CCL8	7 interactors: ACKR2 AKT2 CCR1 CCR3 CCR5 DDX39A PIK3R1
Entrez ID		1238	6358
HPRD ID		09095	03231
Ensembl ID		ENSG00000144648	ENSG00000213494
Uniprot IDs		O00590	Q16627
PDB IDs			2Q8R 2Q8T
Enriched GO Terms of Interacting Partners?		Cell Chemotaxis Chemotaxis Cell Migration Locomotion Immune Response Cell Motility Cellular Calcium Ion Homeostasis Calcium Ion Homeostasis Movement Of Cell Or Subcellular Component Cellular Metal Ion Homeostasis Inflammatory Response Response To External Stimulus Cellular Cation Homeostasis Cellular Ion Homeostasis Metal Ion Homeostasis Regulation Of Leukocyte Migration Cellular Chemical Homeostasis Immune System Process Ion Homeostasis Cellular Homeostasis Leukocyte Chemotaxis Eosinophil Chemotaxis Leukocyte Migration Chemical Homeostasis Eosinophil Migration Positive Regulation Of Leukocyte Chemotaxis Regulation Of Lymphocyte Migration Defense Response Positive Regulation Of Leukocyte Migration Positive Regulation Of Chemotaxis Positive Regulation Of Natural Killer Cell Chemotaxis Regulation Of Cell Migration Positive Regulation Of Behavior Regulation Of Cell Motility Granulocyte Chemotaxis Regulation Of Chemotaxis Homeostatic Process Regulation Of Locomotion Regulation Of Cellular Component Movement Positive Regulation Of Cell Migration Positive Regulation Of Cell Motility Regulation Of Behavior Positive Regulation Of Cellular Component Movement Positive Regulation Of Locomotion Monocyte Chemotaxis Negative Regulation Of Leukocyte Tethering Or Rolling Negative Regulation Of Leukocyte Migration Cellular Response To Stimulus Response To Stress Regulation Of Granulocyte Chemotaxis	Chemokine-mediated Signaling Pathway Cellular Response To Organic Substance Inflammatory Response Cytokine-mediated Signaling Pathway Dendritic Cell Chemotaxis Locomotion Cellular Chemical Homeostasis Response To Organic Substance Positive Regulation Of Cytosolic Calcium Ion Concentration Defense Response Cellular Response To Cytokine Stimulus Chemotaxis Cytosolic Calcium Ion Homeostasis Dendritic Cell Migration Cellular Homeostasis Response To Cytokine Leukocyte Migration Cell Surface Receptor Signaling Pathway Positive Regulation Of Glucose Import Chemical Homeostasis Positive Regulation Of Glucose Transport Cellular Calcium Ion Homeostasis Calcium Ion Homeostasis Establishment Of Localization In Cell Positive Regulation Of Cell Motility Positive Regulation Of Cellular Component Movement Cellular Defense Response Positive Regulation Of Locomotion Regulation Of Glucose Import Regulation Of Osteoclast Differentiation Cellular Metal Ion Homeostasis G-protein Coupled Receptor Signaling Pathway Cellular Localization Cellular Cation Homeostasis Cellular Ion Homeostasis Metal Ion Homeostasis Immune Response Regulation Of Glucose Transport NFAT Protein Import Into Nucleus Homeostatic Process Viral Process Leukocyte Chemotaxis Ion Homeostasis Regulation Of Myeloid Leukocyte Differentiation Transport Regulation Of Cell Migration Intracellular Transport Transcription Factor Import Into Nucleus Regulation Of Cell Motility Signal Transduction
Tagcloud ?			17f 28a 6ckine ccl13 ccl16 ccl17 ccl18 ccl19 ccl21 ccl22 ccl23 ccl25 ccl26 ccl27 ccl28 ccl7 ccl8 ctack cxcl11 cxcl3 cxcl7 il18 lymphotactin mpif parc tarc teck tnfsf14 xcl1
Tagcloud (Difference) ?			17f 28a 6ckine ccl13 ccl16 ccl17 ccl18 ccl19 ccl21 ccl22 ccl23 ccl25 ccl26 ccl27 ccl28 ccl7 ccl8 ctack cxcl11 cxcl3 cxcl7 il18 lymphotactin mpif parc tarc teck tnfsf14 xcl1
Tagcloud (Intersection) ?