CCR8 and CCL16

Number of citations of the paper that reports this interaction (PMID 10910894)
8

Data Source:
HPRD (in vivo, in vitro)

		CCR8	CCL16
Gene Name		chemokine (C-C motif) receptor 8	chemokine (C-C motif) ligand 16
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Plasma Membrane Integral Component Of Plasma Membrane	Extracellular Region Extracellular Space
	Molecular Function	Chemokine Receptor Activity Coreceptor Activity C-C Chemokine Receptor Activity	Chemokine Activity Chemoattractant Activity
	Biological Process	Chemotaxis Immune Response Cell Adhesion G-protein Coupled Receptor Signaling Pathway Positive Regulation Of Cytosolic Calcium Ion Concentration Chemokine-mediated Signaling Pathway	Chemotaxis Inflammatory Response Immune Response Cell Communication Cell-cell Signaling Positive Chemotaxis Cell Chemotaxis
Pathways		Defective ACTH causes Obesity and Pro-opiomelanocortinin deficiency (POMCD) Signaling by GPCR GPCR downstream signaling Peptide ligand-binding receptors Chemokine receptors bind chemokines Class A/1 (Rhodopsin-like receptors) G alpha (i) signalling events Metabolic disorders of biological oxidation enzymes GPCR ligand binding	Defective ACTH causes Obesity and Pro-opiomelanocortinin deficiency (POMCD) Signaling by GPCR GPCR downstream signaling Peptide ligand-binding receptors Chemokine receptors bind chemokines Class A/1 (Rhodopsin-like receptors) G alpha (i) signalling events Metabolic disorders of biological oxidation enzymes GPCR ligand binding
Drugs
Diseases
GWAS
Protein-Protein Interactions		6 interactors: CCL1 CCL16 CCL17 CCL4 TPST1 TPST2	4 interactors: CCR1 CCR5 CCR8 HRH4
Entrez ID		1237	6360
HPRD ID		03497	03233
Ensembl ID		ENSG00000179934	ENSG00000161573
Uniprot IDs		P51685	O15467
PDB IDs
Enriched GO Terms of Interacting Partners?		Cell Chemotaxis Peptidyl-tyrosine Sulfation Protein Sulfation Inflammatory Response Sulfation Chemotaxis Cell Migration Cell Motility Locomotion Immune Response Defense Response Movement Of Cell Or Subcellular Component Response To External Stimulus Prevention Of Polyspermy Immune System Process Cell-cell Signaling Positive Regulation Of Natural Killer Cell Chemotaxis Negative Regulation By Host Of Viral Transcription Sulfur Compound Metabolic Process Fusion Of Sperm To Egg Plasma Membrane Plasma Membrane Fusion Egg Activation Response To Stress Negative Regulation Of Viral Transcription Negative Regulation Of Myoblast Differentiation Positive Regulation Of Calcium-mediated Signaling Positive Chemotaxis Regulation Of Lymphocyte Migration Interaction With Symbiont Regulation Of Myoblast Differentiation Regulation Of Calcium-mediated Signaling Negative Regulation Of Muscle Cell Differentiation Positive Regulation Of Leukocyte Chemotaxis	Positive Regulation Of Cytosolic Calcium Ion Concentration Cytosolic Calcium Ion Homeostasis Cellular Calcium Ion Homeostasis Calcium Ion Homeostasis Chemokine-mediated Signaling Pathway Cellular Metal Ion Homeostasis Cellular Cation Homeostasis Cellular Ion Homeostasis Metal Ion Homeostasis Cellular Chemical Homeostasis Ion Homeostasis Cellular Homeostasis Chemical Homeostasis Dendritic Cell Chemotaxis G-protein Coupled Receptor Signaling Pathway Dendritic Cell Migration Homeostatic Process Inflammatory Response Cytokine-mediated Signaling Pathway Cellular Response To Cytokine Stimulus Chemotaxis Response To Cytokine Leukocyte Chemotaxis Cell Chemotaxis Cell Surface Receptor Signaling Pathway Leukocyte Migration Locomotion Immune Response Defense Response Calcium Ion Transport Release Of Sequestered Calcium Ion Into Cytosol By Sarcoplasmic Reticulum Response To External Stimulus Positive Regulation Of Monocyte Chemotaxis Sarcoplasmic Reticulum Calcium Ion Transport Cellular Response To Organic Substance Regulation Of Monocyte Chemotaxis Signal Transduction Immune System Process Signaling Negative Regulation Of Bone Mineralization Cell Communication Negative Regulation Of Biomineral Tissue Development Response To Cholesterol Regulation Of MAPK Cascade Response To Organic Substance Positive Regulation Of Osteoclast Differentiation Release Of Sequestered Calcium Ion Into Cytosol Cellular Response To Stimulus Regulation Of Sequestering Of Calcium Ion Cell Migration
Tagcloud ?		3p21 bimodal call chemokine chemokines chemotaxis chemr1 ckr cloning cxcr1 cxcr4 faint freshly l1 leukocytes lymphocytes mobilization nomenclature phytohemagglutinin responsiveness served stably stromal subnanomolar ter1 termed transfected unusual	17f 28a 6ckine ccl13 ccl14 ccl17 ccl18 ccl19 ccl21 ccl22 ccl23 ccl25 ccl26 ccl27 ccl28 ccl7 ccl8 ctack cxcl11 cxcl3 cxcl7 il18 lymphotactin mpif parc tarc teck tnfsf14 xcl1
Tagcloud (Difference) ?		3p21 bimodal call chemokine chemokines chemotaxis chemr1 ckr cloning cxcr1 cxcr4 faint freshly l1 leukocytes lymphocytes mobilization nomenclature phytohemagglutinin responsiveness served stably stromal subnanomolar ter1 termed transfected unusual	17f 28a 6ckine ccl13 ccl14 ccl17 ccl18 ccl19 ccl21 ccl22 ccl23 ccl25 ccl26 ccl27 ccl28 ccl7 ccl8 ctack cxcl11 cxcl3 cxcl7 il18 lymphotactin mpif parc tarc teck tnfsf14 xcl1
Tagcloud (Intersection) ?