CNTROB and LYST

Number of citations of the paper that reports this interaction (PMID 11984006)
18

Data Source:
HPRD (two hybrid)

		CNTROB	LYST
Gene Name		centrobin, centrosomal BRCA2 interacting protein	lysosomal trafficking regulator
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Cytoplasm Centrosome Centriole	Cytosol Endomembrane System Microtubule Cytoskeleton Extrinsic Component Of Membrane
	Molecular Function	Protein Binding Protein Domain Specific Binding	Protein Binding Phospholipid Binding
	Biological Process	Centriole Replication Centrosome Separation Mitotic Cytokinetic Process	Neutrophil Mediated Immunity T Cell Mediated Immunity Phospholipid Metabolic Process Microtubule-based Process Lysosome Organization Blood Coagulation Leukocyte Chemotaxis Melanosome Organization Endosome To Lysosome Transport Via Multivesicular Body Sorting Pathway Positive Regulation Of Natural Killer Cell Activation Secretion Of Lysosomal Enzymes Mast Cell Secretory Granule Organization Natural Killer Cell Mediated Cytotoxicity Response To Drug Defense Response To Bacterium Defense Response To Protozoan Pigmentation Defense Response To Virus Phospholipid Homeostasis
Pathways
Drugs
Diseases
GWAS
Protein-Protein Interactions		4 interactors: APTX COASY LYST TTC23	24 interactors: ATN1 CALM1 CELF4 CENPJ CNTROB CSNK2B DGCR14 DNAJC14 EFS ESRRA HGS HNRNPM KPNB1 MED12 MRPL17 MRPS31 NCDN PCBP4 TNNI3 VTA1 YWHAB YWHAQ YWHAZ ZNF521
Entrez ID		116840	1130
HPRD ID		13991	06060
Ensembl ID		ENSG00000170037	ENSG00000143669
Uniprot IDs		Q8N137	Q99698
PDB IDs
Enriched GO Terms of Interacting Partners?		Mast Cell Secretory Granule Organization Polynucleotide 3' Dephosphorylation Endosome To Lysosome Transport Via Multivesicular Body Sorting Pathway Endosome Transport Via Multivesicular Body Sorting Pathway Secretion Of Lysosomal Enzymes Phospholipid Homeostasis Pantothenate Metabolic Process DNA Ligation Phosphate-containing Compound Metabolic Process Coenzyme A Biosynthetic Process Early Endosome To Late Endosome Transport Neutrophil Mediated Immunity Melanosome Organization Single Strand Break Repair Pigment Granule Organization Defense Response To Protozoan Natural Killer Cell Mediated Cytotoxicity Positive Regulation Of Natural Killer Cell Activation Coenzyme A Metabolic Process Natural Killer Cell Mediated Immunity Response To Protozoan DNA Catabolic Process, Exonucleolytic Leukocyte Mediated Cytotoxicity T Cell Mediated Immunity Secretory Granule Organization Organophosphate Metabolic Process Anion Homeostasis Lysosome Organization Cellular Pigmentation Water-soluble Vitamin Metabolic Process	Positive Regulation Of Protein Insertion Into Mitochondrial Membrane Involved In Apoptotic Signaling Pathway Positive Regulation Of Mitochondrial Outer Membrane Permeabilization Involved In Apoptotic Signaling Pathway Regulation Of Mitochondrial Outer Membrane Permeabilization Involved In Apoptotic Signaling Pathway Positive Regulation Of Mitochondrion Organization Mitochondrion Organization Protein Targeting Alternative MRNA Splicing, Via Spliceosome Regulation Of Mitochondrion Organization Centriole Replication Membrane Organization Gene Expression Protein Transport Centriole Assembly Establishment Of Protein Localization Epidermal Growth Factor Receptor Signaling Pathway Multicellular Organismal Development Centrosome Duplication ERBB Signaling Pathway Positive Regulation Of Transport Substantia Nigra Development Regulation Of Intracellular Transport Intrinsic Apoptotic Signaling Pathway Nervous System Development Positive Regulation Of Apoptotic Signaling Pathway MRNA Splicing, Via Spliceosome RNA Splicing, Via Transesterification Reactions Neural Nucleus Development Intracellular Protein Transport Centrosome Cycle Protein Localization Positive Regulation Of Intracellular Transport Apoptotic Process Establishment Of Localization In Cell Developmental Process Mitochondrial Translational Elongation Mitochondrial Translational Initiation Mitochondrial Translational Termination Regulation Of Systemic Arterial Blood Pressure By Ischemic Conditions Programmed Cell Death Intracellular Transport Regulation Of Cellular Localization Cell Death Death Anatomical Structure Development Mitochondrial Translation System Development Midbrain Development Golgi Reassembly Positive Regulation Of Cyclic-nucleotide Phosphodiesterase Activity RNA Splicing
Tagcloud ?			ataxin atp13a2 atxn3 b12 cag cgg chediak coexist cytopathies fmr1 fragile gaucher gba glucocerebrosidase hereditary higashi idiopathic joseph kufor levodopa machado park2 parkin parkinsonism pn polg1 premutation rakeb tremor
Tagcloud (Difference) ?			ataxin atp13a2 atxn3 b12 cag cgg chediak coexist cytopathies fmr1 fragile gaucher gba glucocerebrosidase hereditary higashi idiopathic joseph kufor levodopa machado park2 parkin parkinsonism pn polg1 premutation rakeb tremor
Tagcloud (Intersection) ?