ADAP1 and AP3B2

Number of citations of the paper that reports this interaction (PMID 12565890)
3

Data Source:
HPRD (in vitro)

		ADAP1	AP3B2
Gene Name		ArfGAP with dual PH domains 1	adaptor-related protein complex 3, beta 2 subunit
Image			No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleus Cytoplasm Plasma Membrane	Nucleoplasm Cytoplasm Golgi Apparatus AP-3 Adaptor Complex COPI-coated Vesicle Clathrin-coated Vesicle Membrane
	Molecular Function	Protein Binding Phosphatidylinositol-3,4,5-trisphosphate Binding ARF GTPase Activator Activity Zinc Ion Binding Inositol 1,3,4,5 Tetrakisphosphate Binding	Transporter Activity
	Biological Process	Cell Surface Receptor Signaling Pathway Regulation Of ARF GTPase Activity Regulation Of GTPase Activity Positive Regulation Of GTPase Activity	Intracellular Protein Transport Post-Golgi Vesicle-mediated Transport Anterograde Axon Cargo Transport Anterograde Synaptic Vesicle Transport
Pathways
Drugs
Diseases
GWAS			Lipoprotein-associated phospholipase A2 activity change in response to statin therapy ( 23118302)
Protein-Protein Interactions		23 interactors: ANP32A AP3B2 CSNK1A1 DVL3 GADD45A GOLGA2 GSK3B NCL PIK3CA PRKCA PRKCE PRKCI PRKCZ PRKD1 PSME3 PURA RANBP9 RPS9 SDCBP2 SF3A3 SRSF2 SUB1 SUPV3L1	6 interactors: ADAP1 AP3S1 ATM CLTC CSNK1A1 RUFY1
Entrez ID		11033	8120
HPRD ID		09733	03699
Ensembl ID		ENSG00000105963	ENSG00000103723
Uniprot IDs		O75689	B7ZKR7 B7ZKS0 Q13367
PDB IDs		3FEH 3FM8 3LJU 3MDB
Enriched GO Terms of Interacting Partners?		Peptidyl-serine Phosphorylation Intracellular Signal Transduction Intracellular Transport Regulation Of Cellular Amino Acid Metabolic Process Positive Regulation Of Cellular Metabolic Process Regulation Of Cellular Ketone Metabolic Process Positive Regulation Of Cellular Protein Metabolic Process Regulation Of Cellular Protein Metabolic Process Establishment Of Localization In Cell Positive Regulation Of Phosphorylation Cellular Response To Growth Factor Stimulus Positive Regulation Of Protein Metabolic Process Enzyme Linked Receptor Protein Signaling Pathway Response To Growth Factor Positive Regulation Of Protein Modification Process Positive Regulation Of Signal Transduction Neurotrophin TRK Receptor Signaling Pathway Regulation Of Protein Metabolic Process Transmembrane Receptor Protein Tyrosine Kinase Signaling Pathway Neurotrophin Signaling Pathway Negative Regulation Of Cell Death Vascular Endothelial Growth Factor Receptor Signaling Pathway Positive Regulation Of Metabolic Process Positive Regulation Of Protein Phosphorylation Regulation Of Protein Phosphorylation Cellular Localization Regulation Of Nitrogen Compound Metabolic Process Positive Regulation Of Canonical Wnt Signaling Pathway Positive Regulation Of Catalytic Activity Regulation Of Cell Death Positive Regulation Of Wnt Signaling Pathway Negative Regulation Of Apoptotic Process Negative Regulation Of Programmed Cell Death Regulation Of Phosphorylation Epidermal Growth Factor Receptor Signaling Pathway Protein Phosphorylation Fibroblast Growth Factor Receptor Signaling Pathway ERBB Signaling Pathway Regulation Of MAPK Cascade Positive Regulation Of Cell Adhesion Regulation Of Glucose Import Signaling Cellular Response To Fibroblast Growth Factor Stimulus Cell Communication Regulation Of Metabolic Process Platelet Activation Response To Fibroblast Growth Factor Negative Regulation Of Glial Cell Apoptotic Process Anatomical Structure Morphogenesis Positive Regulation Of Phospholipase Activity	Vesicle-mediated Transport Signal Transduction Involved In Mitotic G2 DNA Damage Checkpoint Peptidyl-serine Phosphorylation Endocytosis Mitotic Cell Cycle Process Mitotic Cell Cycle Regulation Of Cellular Component Organization Negative Regulation Of Hyaluronan Biosynthetic Process Pre-B Cell Allelic Exclusion Cell Cycle Process Pre-B Cell Differentiation Histone MRNA Catabolic Process Replicative Senescence Mitotic Nuclear Division Negative Regulation Of G2/M Transition Of Mitotic Cell Cycle Immature B Cell Differentiation DNA Damage Induced Protein Phosphorylation Negative Regulation Of Cell Cycle G2/M Phase Transition Cell Cycle Positive Regulation Of DNA Damage Response, Signal Transduction By P53 Class Mediator Protein Transport Lipoprotein Catabolic Process
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