AP3B2 and CLTC

Number of citations of the paper that reports this interaction (PMID 9545220)
106

Data Source:
HPRD (in vitro)

		AP3B2	CLTC
Gene Name		adaptor-related protein complex 3, beta 2 subunit	clathrin, heavy chain (Hc)
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleoplasm Cytoplasm Golgi Apparatus AP-3 Adaptor Complex COPI-coated Vesicle Clathrin-coated Vesicle Membrane	Cytoplasm Spindle Cytosol Plasma Membrane Focal Adhesion Membrane Clathrin Coat Clathrin Coat Of Trans-Golgi Network Vesicle Clathrin Coat Of Coated Pit Clathrin-coated Vesicle Clathrin-coated Endocytic Vesicle Membrane Vesicle Trans-Golgi Network Membrane Melanosome Intracellular Membrane-bounded Organelle Protein Complex Extracellular Vesicular Exosome Clathrin Complex
	Molecular Function	Transporter Activity	Double-stranded RNA Binding Structural Molecule Activity Protein Binding Protein Kinase Binding Clathrin Light Chain Binding Poly(A) RNA Binding
	Biological Process	Intracellular Protein Transport Post-Golgi Vesicle-mediated Transport Anterograde Axon Cargo Transport Anterograde Synaptic Vesicle Transport	Osteoblast Differentiation Intracellular Protein Transport Post-Golgi Vesicle-mediated Transport Receptor-mediated Endocytosis Mitotic Nuclear Division Antigen Processing And Presentation Of Exogenous Peptide Antigen Via MHC Class II Receptor Internalization Transferrin Transport Membrane Organization Negative Regulation Of Hyaluronan Biosynthetic Process Negative Regulation Of Protein Localization To Plasma Membrane
Pathways			Formation of annular gap junctions EPH-ephrin mediated repulsion of cells Axon guidance Gap junction degradation Gap junction trafficking and regulation Gap junction trafficking WNT5A-dependent internalization of FZD4 EPH-Ephrin signaling Signaling by Wnt PCP/CE pathway beta-catenin independent WNT signaling
Drugs
Diseases
GWAS		Lipoprotein-associated phospholipase A2 activity change in response to statin therapy ( 23118302)
Protein-Protein Interactions		6 interactors: ADAP1 AP3S1 ATM CLTC CSNK1A1 RUFY1	60 interactors: AMPH AP1B1 AP1G1 AP2A2 AP2B1 AP3B1 AP3B2 ARMCX3 ARR3 ARRB1 ARRB2 C10orf88 CLINT1 CLTA CLTB DNAJC6 EHD1 EP300 EPN1 EPN2 ERG FYN GAK GGA1 GGA2 GGA3 GRIN1 GRIN2D HGS HIP1 HIP1R ITSN1 KIT LDLRAP1 MAP3K10 NCALD NDRG1 OCRL PICALM PPP1CA PPP1CC PRKACA PXN QARS SCYL2 SNX5 SNX9 SRC STAM STAMBP SYNJ1 TFAP2A TNK2 TOM1 VCL WNK1 XRCC6 YWHAG YWHAQ ZFYVE9
Entrez ID		8120	1213
HPRD ID		03699	00350
Ensembl ID		ENSG00000103723	ENSG00000141367
Uniprot IDs		B7ZKR7 B7ZKS0 Q13367	Q00610
PDB IDs			2XZG 4G55
Enriched GO Terms of Interacting Partners?		Vesicle-mediated Transport Signal Transduction Involved In Mitotic G2 DNA Damage Checkpoint Peptidyl-serine Phosphorylation Endocytosis Mitotic Cell Cycle Process Mitotic Cell Cycle Regulation Of Cellular Component Organization Negative Regulation Of Hyaluronan Biosynthetic Process Pre-B Cell Allelic Exclusion Cell Cycle Process Pre-B Cell Differentiation Histone MRNA Catabolic Process Replicative Senescence Mitotic Nuclear Division Negative Regulation Of G2/M Transition Of Mitotic Cell Cycle Immature B Cell Differentiation DNA Damage Induced Protein Phosphorylation Negative Regulation Of Cell Cycle G2/M Phase Transition Cell Cycle Positive Regulation Of DNA Damage Response, Signal Transduction By P53 Class Mediator Protein Transport Lipoprotein Catabolic Process	Vesicle-mediated Transport Endocytosis Transport Establishment Of Localization In Cell Intracellular Transport Cellular Localization Intracellular Protein Transport Cellular Protein Localization Epidermal Growth Factor Receptor Signaling Pathway Regulation Of Vesicle-mediated Transport ERBB Signaling Pathway Protein Transport Signaling Establishment Of Protein Localization Cell Communication Enzyme Linked Receptor Protein Signaling Pathway Protein Localization Negative Regulation Of Epidermal Growth Factor Receptor Signaling Pathway Regulation Of Endocytosis Negative Regulation Of ERBB Signaling Pathway Cellular Response To Growth Factor Stimulus Regulation Of Signaling Response To Growth Factor Membrane Organization Positive Regulation Of Transport Regulation Of Signal Transduction Negative Regulation Of Signal Transduction Transmembrane Receptor Protein Tyrosine Kinase Signaling Pathway Cellular Response To Stimulus Regulation Of Epidermal Growth Factor Receptor Signaling Pathway Regulation Of ERBB Signaling Pathway Synaptic Transmission Endosomal Transport Negative Regulation Of Signaling Post-Golgi Vesicle-mediated Transport Signal Transduction Regulation Of Defense Response To Virus By Virus Nervous System Development Receptor-mediated Endocytosis Regulation Of Cellular Component Organization Cell-cell Signaling Response To Stimulus Positive Regulation Of Receptor-mediated Endocytosis Neurotrophin TRK Receptor Signaling Pathway Neurotrophin Signaling Pathway Receptor Internalization Regulation Of Protein Metabolic Process Cell Surface Receptor Signaling Pathway Ephrin Receptor Signaling Pathway Positive Regulation Of Endocytosis
Tagcloud ?			alk clathrin contribution deregulated diffuse dlbcl dlbcls encoding feature formed lm1 lymphoma lymphomas maintenance nanomolar nod nvp otherwise providing rationale refractory repressed scid signalling subtype sustained tae684 thereby xenotransplant
Tagcloud (Difference) ?			alk clathrin contribution deregulated diffuse dlbcl dlbcls encoding feature formed lm1 lymphoma lymphomas maintenance nanomolar nod nvp otherwise providing rationale refractory repressed scid signalling subtype sustained tae684 thereby xenotransplant
Tagcloud (Intersection) ?