SF3B2 and HNRNPC

Number of citations of the paper that reports this interaction (PMID 22365833)
24

Data Source:
BioGRID (two hybrid, two hybrid)

		SF3B2	HNRNPC
Gene Name		splicing factor 3b, subunit 2, 145kDa	heterogeneous nuclear ribonucleoprotein C (C1/C2)
Image
Gene Ontology Annotations	Cellular Component	Nucleoplasm Spliceosomal Complex U12-type Spliceosomal Complex Catalytic Step 2 Spliceosome	Nuclear Chromatin Nucleus Nucleoplasm Spliceosomal Complex Cytosol Membrane Protein Complex Extracellular Vesicular Exosome Catalytic Step 2 Spliceosome
	Molecular Function	Protein Binding Poly(A) RNA Binding	Nucleotide Binding RNA Polymerase II Core Promoter Proximal Region Sequence-specific DNA Binding RNA Polymerase II Distal Enhancer Sequence-specific DNA Binding RNA Binding MRNA 3'-UTR Binding Protein Binding Poly(U) RNA Binding Nucleosomal DNA Binding Identical Protein Binding Poly(A) RNA Binding
	Biological Process	MRNA Splicing, Via Spliceosome MRNA Processing RNA Splicing Gene Expression Viral Process	MRNA Splicing, Via Spliceosome Osteoblast Differentiation RNA Splicing Gene Expression ATP-dependent Chromatin Remodeling 3'-UTR-mediated MRNA Stabilization
Pathways		Processing of Capped Intron-Containing Pre-mRNA mRNA Splicing mRNA Splicing - Minor Pathway mRNA Splicing - Major Pathway	Processing of Capped Intron-Containing Pre-mRNA mRNA Splicing mRNA Splicing - Major Pathway
Drugs
Diseases
GWAS		Bipolar disorder ( 21926972)	Bipolar disorder ( 21738484)
Protein-Protein Interactions		25 interactors: APBB1 APP C7orf25 C8orf33 CSNK2A1 ERG FRA10AC1 HNRNPC KDM1A KIAA0368 LSM2 LSM3 PCBP2 PRPF40A RBM7 RBM8A SF3B4 SMAD3 SNRNP200 TCERG1 THOC1 TOE1 TTC14 U2AF1 ZCCHC10	48 interactors: AP1M1 BARD1 BRCA1 BRCA2 BRIP1 BTRC CCDC85B CDKN2A CELF1 CSNK1A1 CSNK2A1 CSNK2A2 DHX9 EPS8 ERG FAS FXR2 GRB2 HNRNPD IL7R KHDRBS3 KPNA2 KPNA3 KPNA4 KRAS LMO2 LMO3 PALB2 PDGFB PHKB PIN1 PRKDC PTBP2 RAD51 RALY RALYL RBM41 SDCBP SF3B2 SMARCD1 SREK1 SRPK2 SUMO1 SUMO1P1 UBE2I YWHAQ ZFYVE26 ZNF581
Entrez ID		10992	3183
HPRD ID		10410	01243
Ensembl ID		ENSG00000087365	ENSG00000092199
Uniprot IDs		Q13435	P07910
PDB IDs		2DO5	1TXP 1WF2 3LN4
Enriched GO Terms of Interacting Partners?		RNA Processing MRNA Processing RNA Splicing MRNA Metabolic Process RNA Metabolic Process Gene Expression MRNA Splicing, Via Spliceosome RNA Splicing, Via Transesterification Reactions Nucleobase-containing Compound Metabolic Process Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Cellular Nitrogen Compound Metabolic Process Nitrogen Compound Metabolic Process Cellular Metabolic Process MRNA Export From Nucleus Transcription, DNA-templated RNA Export From Nucleus RNA Biosynthetic Process MRNA 3'-end Processing Regulation Of Cell Cycle RNA 3'-end Processing Nuclear Export MRNA Transport Regulation Of Response To DNA Damage Stimulus Osteoblast Differentiation RNA Transport Exonucleolytic Nuclear-transcribed MRNA Catabolic Process Involved In Deadenylation-dependent Decay Nuclear-transcribed MRNA Catabolic Process, Exonucleolytic Nuclear-transcribed MRNA Catabolic Process RNA Localization MRNA Catabolic Process Regulation Of Gene Expression Negative Regulation Of Cell Cycle RNA Catabolic Process Posttranscriptional Regulation Of Gene Expression Cellular Macromolecule Catabolic Process Metabolic Process Termination Of RNA Polymerase II Transcription Transcription From RNA Polymerase II Promoter Regulation Of Cell Cycle Process Negative Regulation Of Protein Metabolic Process Apoptotic Process Nuclear-transcribed MRNA Catabolic Process, Deadenylation-dependent Decay Regulation Of RNA Metabolic Process Cellular Macromolecule Biosynthetic Process Positive Regulation Of Transforming Growth Factor Beta3 Production Regulation Of Primitive Erythrocyte Differentiation Negative Regulation Of Thymidylate Synthase Biosynthetic Process Negative Regulation Of Potassium Ion Export Negative Regulation Of Isotype Switching To IgA Isotypes	Nucleobase-containing Compound Metabolic Process Cellular Nitrogen Compound Metabolic Process Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Regulation Of Gene Expression Regulation Of Metabolic Process Regulation Of Nitrogen Compound Metabolic Process Cell Cycle Process Nitrogen Compound Metabolic Process Double-strand Break Repair Via Homologous Recombination Recombinational Repair Cellular Response To Stimulus Cell Cycle Double-strand Break Repair Negative Regulation Of Cellular Metabolic Process Regulation Of RNA Metabolic Process Positive Regulation Of Metabolic Process MRNA Splicing, Via Spliceosome RNA Splicing RNA Splicing, Via Transesterification Reactions Cellular Metabolic Process Regulation Of Cell Cycle Cellular Response To Organic Substance MRNA Processing DNA Repair Cellular Response To Cytokine Stimulus Regulation Of Cellular Process Response To Stimulus Positive Regulation Of Signal Transduction Cellular Response To DNA Damage Stimulus Cellular Response To Stress DNA Metabolic Process Regulation Of Cell Cycle Process Negative Regulation Of Gene Expression DNA Recombination Response To Cytokine Regulation Of Protein Metabolic Process MRNA Metabolic Process Response To Organic Substance Regulation Of Cellular Component Organization Response To Ionizing Radiation Regulation Of Transcription, DNA-templated Regulation Of Cellular Protein Metabolic Process Developmental Process Positive Regulation Of Cellular Metabolic Process NLS-bearing Protein Import Into Nucleus RNA Processing Regulation Of Nucleic Acid-templated Transcription Regulation Of RNA Biosynthetic Process Regulation Of Mitotic Cell Cycle
Tagcloud ?			17th 2d appreciation coordinately coupling d deep dihydroxyvitamin entitled epigenome exerts expanded extra fine hormones issue linking locations microrna ribonucleoprotein special splicing steroid transcriptionally tuning vdr vdre vitamin workshop
Tagcloud (Difference) ?			17th 2d appreciation coordinately coupling d deep dihydroxyvitamin entitled epigenome exerts expanded extra fine hormones issue linking locations microrna ribonucleoprotein special splicing steroid transcriptionally tuning vdr vdre vitamin workshop
Tagcloud (Intersection) ?