SERINC3 and RPS15

Number of citations of the paper that reports this interaction (PMID 21988832)
14

Data Source:
BioGRID (two hybrid)

		SERINC3	RPS15
Gene Name		serine incorporator 3	ribosomal protein S15
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Golgi Apparatus Plasma Membrane Integral Component Of Membrane	Nucleus Nucleoplasm Cytoplasm Cytosol Focal Adhesion Membrane Cytosolic Small Ribosomal Subunit
	Molecular Function	L-serine Transmembrane Transporter Activity	DNA Binding Structural Constituent Of Ribosome Protein Binding Poly(A) RNA Binding
	Biological Process	Phosphatidylserine Metabolic Process Sphingolipid Metabolic Process L-serine Transport Positive Regulation Of Endoplasmic Reticulum Stress-induced Intrinsic Apoptotic Signaling Pathway	Ribosomal Small Subunit Assembly Ribosomal Small Subunit Export From Nucleus Nuclear-transcribed MRNA Catabolic Process, Nonsense-mediated Decay Osteoblast Differentiation RRNA Processing Translation Translational Initiation Translational Elongation Translational Termination SRP-dependent Cotranslational Protein Targeting To Membrane Gene Expression Viral Process Viral Life Cycle Viral Transcription Ribosomal Small Subunit Biogenesis Cellular Protein Metabolic Process
Pathways			Nonsense-Mediated Decay (NMD) Translation initiation complex formation Translation SRP-dependent cotranslational protein targeting to membrane Eukaryotic Translation Termination Peptide chain elongation Influenza Infection Viral mRNA Translation L13a-mediated translational silencing of Ceruloplasmin expression Influenza Life Cycle Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC) Ribosomal scanning and start codon recognition Formation of the ternary complex, and subsequently, the 43S complex Influenza Viral RNA Transcription and Replication GTP hydrolysis and joining of the 60S ribosomal subunit Eukaryotic Translation Initiation Activation of the mRNA upon binding of the cap-binding complex and eIFs, and subsequent binding to 43S Formation of a pool of free 40S subunits Eukaryotic Translation Elongation Cap-dependent Translation Initiation Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)
Drugs
Diseases
GWAS		Bipolar disorder ( 22925353) Ulcerative colitis ( 21297633)
Protein-Protein Interactions		2 interactors: BMP10 RPS15	6 interactors: G2E3 PLA2G12A RAPGEF1 RPS4X SERINC3 UPF2
Entrez ID		10955	6209
HPRD ID		06201	01613
Ensembl ID		ENSG00000132824	ENSG00000115268
Uniprot IDs		B4DUE9 Q13530	K7ELC2 K7EM56 P62841
PDB IDs			2ZKQ 3J3A
Enriched GO Terms of Interacting Partners?		Ribosomal Small Subunit Export From Nucleus Organelle Assembly Positive Regulation Of Sarcomere Organization Regulation Of Cardiac Muscle Hypertrophy In Response To Stress Atrial Cardiac Muscle Tissue Morphogenesis Ribosomal Subunit Export From Nucleus Negative Regulation Of Cardiac Muscle Hypertrophy Negative Regulation Of Muscle Hypertrophy Ribosomal Small Subunit Assembly Positive Regulation Of Cell Proliferation Involved In Heart Morphogenesis Pathway-restricted SMAD Protein Phosphorylation Heart Trabecula Formation Adult Heart Development Regulation Of Sarcomere Organization Positive Regulation Of Cardiac Muscle Hypertrophy Ventricular Cardiac Muscle Cell Development Cardiac Muscle Cell Proliferation Positive Regulation Of Organelle Assembly Heart Trabecula Morphogenesis Ribosome Assembly Ventricular Cardiac Muscle Cell Differentiation Regulation Of Cardiac Muscle Hypertrophy Activin Receptor Signaling Pathway Positive Regulation Of Cardiac Muscle Cell Proliferation Cardiac Atrium Morphogenesis Regulation Of Heart Morphogenesis Cardiac Muscle Tissue Growth Negative Regulation Of Endothelial Cell Migration Positive Regulation Of Heart Growth Ribosomal Small Subunit Biogenesis Ventricular Cardiac Muscle Tissue Morphogenesis Positive Regulation Of Pathway-restricted SMAD Protein Phosphorylation Regulation Of Cardiac Muscle Cell Proliferation Negative Regulation Of Epithelial Cell Migration Positive Regulation Of Organ Growth Trabecula Morphogenesis Sarcomere Organization Ventricular Cardiac Muscle Tissue Development Regulation Of Pathway-restricted SMAD Protein Phosphorylation SMAD Protein Signal Transduction Cardiac Muscle Tissue Morphogenesis Regulation Of Heart Growth Positive Regulation Of Striated Muscle Cell Differentiation Regulation Of Cardiac Muscle Tissue Development Muscle Tissue Morphogenesis Positive Regulation Of Striated Muscle Tissue Development Positive Regulation Of Muscle Tissue Development Cardiac Muscle Cell Development Muscle Organ Morphogenesis Cardiac Ventricle Morphogenesis	Phosphatidylserine Metabolic Process Nuclear-transcribed MRNA Catabolic Process, Nonsense-mediated Decay Nuclear-transcribed MRNA Catabolic Process Regulation Of Intrinsic Apoptotic Signaling Pathway MRNA Catabolic Process RNA Catabolic Process
Tagcloud ?			abcg2 accepted actb b2m colostrum correct dgat1 elf5 errors gapdh geometric gtp incurred lactating lactation milk mrpl39 normalization ppp1r11 reference rn18s1 rps9 somatic srebf2 steps thereafter uxt yak yaks
Tagcloud (Difference) ?			abcg2 accepted actb b2m colostrum correct dgat1 elf5 errors gapdh geometric gtp incurred lactating lactation milk mrpl39 normalization ppp1r11 reference rn18s1 rps9 somatic srebf2 steps thereafter uxt yak yaks
Tagcloud (Intersection) ?