CXCL13 and CCR10

Number of citations of the paper that reports this interaction (PMID 10706668)
23

Data Source:
HPRD (in vitro)

		CXCL13	CCR10
Gene Name		chemokine (C-X-C motif) ligand 13	chemokine (C-C motif) receptor 10
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Extracellular Region Extracellular Space	Plasma Membrane Integral Component Of Plasma Membrane Cell Surface
	Molecular Function	Chemokine Activity Heparin Binding Fibroblast Growth Factor Binding CXCR5 Chemokine Receptor Binding CCR10 Chemokine Receptor Binding Protein Heterodimerization Activity Receptor Agonist Activity CXCR3 Chemokine Receptor Binding	G-protein Coupled Receptor Activity C-C Chemokine Receptor Activity
	Biological Process	Germinal Center Formation Lymphocyte Chemotaxis Across High Endothelial Venule Chronic Inflammatory Response Regulation Of Humoral Immune Response Inflammatory Response Immune Response Cell Surface Receptor Signaling Pathway G-protein Coupled Receptor Signaling Pathway Positive Regulation Of Cytosolic Calcium Ion Concentration Cell-cell Signaling Positive Regulation Of T Cell Chemotaxis Response To Lipopolysaccharide Activation Of Rap GTPase Activity Positive Regulation Of Integrin Activation Positive Regulation Of Cell-cell Adhesion Mediated By Integrin B Cell Chemotaxis Endothelial Cell Chemotaxis To Fibroblast Growth Factor B Cell Chemotaxis Across High Endothelial Venule Regulation Of Cell Proliferation Defense Response To Bacterium Regulation Of Angiogenesis Lymph Node Development Chemokine-mediated Signaling Pathway Negative Regulation Of Endothelial Cell Chemotaxis To Fibroblast Growth Factor	Chemotaxis Immune Response G-protein Coupled Receptor Signaling Pathway Positive Regulation Of Cytosolic Calcium Ion Concentration Chemokine-mediated Signaling Pathway
Pathways		Defective ACTH causes Obesity and Pro-opiomelanocortinin deficiency (POMCD) Signaling by GPCR GPCR downstream signaling Peptide ligand-binding receptors Chemokine receptors bind chemokines Class A/1 (Rhodopsin-like receptors) G alpha (i) signalling events Metabolic disorders of biological oxidation enzymes GPCR ligand binding	Defective ACTH causes Obesity and Pro-opiomelanocortinin deficiency (POMCD) Signaling by GPCR GPCR downstream signaling Peptide ligand-binding receptors Chemokine receptors bind chemokines Class A/1 (Rhodopsin-like receptors) G alpha (i) signalling events Metabolic disorders of biological oxidation enzymes GPCR ligand binding
Drugs
Diseases
GWAS		Cardiac Troponin-T levels ( 23247143)
Protein-Protein Interactions		8 interactors: ACKR4 CCL19 CCL21 CCR10 CXCR3 CXCR5 EEF1G FGF2	10 interactors: CCL19 CCL2 CCL21 CCL25 CCL27 CCL28 CCL7 CCR7 CXCL13 PRRC2A
Entrez ID		10563	2826
HPRD ID		05513	02586
Ensembl ID		ENSG00000156234
Uniprot IDs		O43927 Q53X90	P46092
PDB IDs
Enriched GO Terms of Interacting Partners?		Chemotaxis Positive Regulation Of Cytosolic Calcium Ion Concentration Response To External Stimulus Cytosolic Calcium Ion Homeostasis Chemokine-mediated Signaling Pathway Locomotion Cellular Calcium Ion Homeostasis Calcium Ion Homeostasis Positive Regulation Of Chemotaxis Positive Regulation Of Behavior Regulation Of Chemotaxis Cellular Metal Ion Homeostasis Positive Regulation Of Phosphatidylinositol 3-kinase Activity Cellular Cation Homeostasis Cellular Ion Homeostasis Regulation Of Ion Homeostasis Metal Ion Homeostasis Release Of Sequestered Calcium Ion Into Cytosol Regulation Of Sequestering Of Calcium Ion Regulation Of Behavior Regulation Of Dendritic Cell Dendrite Assembly Cellular Chemical Homeostasis Calcium Ion Transport Into Cytosol Cytosolic Calcium Ion Transport Ion Homeostasis Immune System Process Regulation Of Phosphatidylinositol 3-kinase Activity Immune Response Regulation Of Lipid Kinase Activity Cellular Homeostasis Response To Organic Substance Establishment Of T Cell Polarity Positive Regulation Of Locomotion Chemical Homeostasis Positive Regulation Of Dendritic Cell Antigen Processing And Presentation Leukocyte Chemotaxis Regulation Of Leukocyte Migration Inflammatory Response Cytokine-mediated Signaling Pathway Positive Regulation Of ERK1 And ERK2 Cascade Dendritic Cell Chemotaxis Positive Regulation Of Glycoprotein Biosynthetic Process Immunological Synapse Formation Leukocyte Activation Positive Regulation Of Glycoprotein Metabolic Process G-protein Coupled Receptor Signaling Pathway Response To Prostaglandin E Cell Chemotaxis Cellular Response To Cytokine Stimulus Regulation Of Cell Migration	Cell Chemotaxis Regulation Of Leukocyte Migration Chemotaxis Positive Regulation Of Leukocyte Chemotaxis Cell Migration Positive Regulation Of Leukocyte Migration Cell Motility Leukocyte Migration Leukocyte Chemotaxis Positive Regulation Of Chemotaxis Regulation Of Cell Migration Cellular Calcium Ion Homeostasis Positive Regulation Of Behavior Calcium Ion Homeostasis Regulation Of Cell Motility Regulation Of Chemotaxis Locomotion Regulation Of Locomotion Immune Response Regulation Of Cellular Component Movement Positive Regulation Of Cell Adhesion Cellular Metal Ion Homeostasis Movement Of Cell Or Subcellular Component Regulation Of Behavior Inflammatory Response Cellular Cation Homeostasis Regulation Of Dendritic Cell Dendrite Assembly Cellular Ion Homeostasis Metal Ion Homeostasis Negative Regulation Of Leukocyte Migration Cellular Chemical Homeostasis Response To External Stimulus Negative Regulation Of Leukocyte Tethering Or Rolling Ion Homeostasis Regulation Of Cell Adhesion Regulation Of Lymphocyte Migration Immune System Process Regulation Of Granulocyte Chemotaxis Positive Regulation Of Cell Migration Establishment Of T Cell Polarity Positive Regulation Of Cell Motility Cellular Homeostasis Regulation Of Immune System Process Positive Regulation Of Cellular Component Movement Positive Regulation Of Locomotion Regulation Of Cell-cell Adhesion Positive Regulation Of Cytosolic Calcium Ion Concentration Positive Regulation Of Dendritic Cell Antigen Processing And Presentation Chemical Homeostasis Positive Regulation Of Cell-matrix Adhesion
Tagcloud ?		aaa aaas adventitial aneurysms aorta arteries atherosclerosis atherothrombosis atherothrombotic ccl19 ccl20 ccl21 chemokine chemokines chemotaxis conditioned contributors converted cryosections evolutive immunofluorescence medium qpcr sma smcs tertiary tlos trigger	allograft allografts alloreactivity archived arrays augur cd138 cd154 cd19 cd27 existed ig iga igg igll1 immunocyte immunocytes intestine itx mucosal prone protracted reconstitution rejecting rejection repopulation serial stap1 undergoes
Tagcloud (Difference) ?		aaa aaas adventitial aneurysms aorta arteries atherosclerosis atherothrombosis atherothrombotic ccl19 ccl20 ccl21 chemokine chemokines chemotaxis conditioned contributors converted cryosections evolutive immunofluorescence medium qpcr sma smcs tertiary tlos trigger	allograft allografts alloreactivity archived arrays augur cd138 cd154 cd19 cd27 existed ig iga igg igll1 immunocyte immunocytes intestine itx mucosal prone protracted reconstitution rejecting rejection repopulation serial stap1 undergoes
Tagcloud (Intersection) ?