SEC23A and CDK18

Number of citations of the paper that reports this interaction (PMID 16091426)
19

Data Source:
HPRD (in vivo, two hybrid)

		SEC23A	CDK18
Gene Name		Sec23 homolog A (S. cerevisiae)	cyclin-dependent kinase 18
Image			No pdb structure
Gene Ontology Annotations	Cellular Component	Golgi Membrane Endoplasmic Reticulum Endoplasmic Reticulum Membrane Cytosol ER To Golgi Transport Vesicle Membrane COPII Vesicle Coat Smooth Endoplasmic Reticulum Membrane Perinuclear Region Of Cytoplasm	Cellular_component
	Molecular Function	Protein Binding Zinc Ion Binding	Cyclin-dependent Protein Serine/threonine Kinase Activity Protein Binding ATP Binding
	Biological Process	Antigen Processing And Presentation Of Peptide Antigen Via MHC Class I Intracellular Protein Transport ER To Golgi Vesicle-mediated Transport Vesicle-mediated Transport Protein N-linked Glycosylation Via Asparagine Antigen Processing And Presentation Of Exogenous Peptide Antigen Via MHC Class II Post-translational Protein Modification Cellular Protein Metabolic Process Small Molecule Metabolic Process COPII Vesicle Coating Membrane Organization	Protein Phosphorylation Regulation Of Cell Cycle
Pathways		Diseases of glycosylation Metabolism of lipids and lipoproteins Defective ALG14 causes congenital myasthenic syndrome (ALG14-CMS) Transport to the Golgi and subsequent modification Defective MGAT2 causes MGAT2-CDG (CDG-2a) Defective ALG1 causes ALG1-CDG (CDG-1k) Antigen Presentation: Folding, assembly and peptide loading of class I MHC Defective MOGS causes MOGS-CDG (CDG-2b) Regulation of cholesterol biosynthesis by SREBP (SREBF) Defective ALG9 causes ALG9-CDG (CDG-1l) Defective MAN1B1 causes MRT15 MHC class II antigen presentation Class I MHC mediated antigen processing & presentation COPII (Coat Protein 2) Mediated Vesicle Transport ER to Golgi Transport Defective ALG11 causes ALG11-CDG (CDG-1p) Defective ALG2 causes ALG2-CDG (CDG-1i) Defective ALG3 causes ALG3-CDG (CDG-1d) Post-translational protein modification Defective DPAGT1 causes DPAGT1-CDG (CDG-1j) and CMSTA2 Defective B4GALT1 causes B4GALT1-CDG (CDG-2d) Defective ALG6 causes ALG6-CDG (CDG-1c) Defective RFT1 causes RFT1-CDG (CDG-1n) Asparagine N-linked glycosylation Defective ALG8 causes ALG8-CDG (CDG-1h) Defective MPDU1 causes MPDU1-CDG (CDG-1f) Defective ALG12 causes ALG12-CDG (CDG-1g) Diseases associated with N-glycosylation of proteins Adaptive Immune System
Drugs
Diseases
GWAS
Protein-Protein Interactions		9 interactors: CDK16 CDK18 DCTN1 GLRA2 NDRG1 SDCBP2 SEC16A SEC24B SEC24C	18 interactors: APP CCDC102B CCDC85B CCNDBP1 CCNK GOLGA2 KIFC3 KRT31 KRT40 LZTS2 MIPOL1 MTUS2 PNMA1 SEC23A TRIM27 TRIM54 TSGA10 YWHAQ
Entrez ID		10484	5129
HPRD ID		06714	01354
Ensembl ID		ENSG00000100934	ENSG00000117266
Uniprot IDs		B3KXI2 F5H365 Q15436	Q07002 Q59G02
PDB IDs		2NUP 2NUT 2YRC 2YRD 3EFO 3EG9 3EGD 3EGX
Enriched GO Terms of Interacting Partners?		COPII Vesicle Coating COPII-coated Vesicle Budding Vesicle Targeting, To, From Or Within Golgi Localization Within Membrane Vesicle Targeting Establishment Of Vesicle Localization Vesicle Localization Membrane Budding Establishment Of Organelle Localization Antigen Processing And Presentation Of Exogenous Peptide Antigen Via MHC Class II Antigen Processing And Presentation Of Peptide Antigen Via MHC Class II ER To Golgi Vesicle-mediated Transport Antigen Processing And Presentation Of Peptide Or Polysaccharide Antigen Via MHC Class II Organelle Localization Establishment Of Localization In Cell Nervous System Development Vesicle Organization Cellular Localization Antigen Processing And Presentation Of Peptide Antigen Vesicle-mediated Transport Golgi Vesicle Transport Intracellular Transport Antigen Processing And Presentation Membrane Organization Neural Nucleus Development Transport Protein N-linked Glycosylation Via Asparagine Protein N-linked Glycosylation Regulation Of Cargo Loading Into COPII-coated Vesicle Cochlear Nucleus Development System Development Antigen Processing And Presentation Of Peptide Antigen Via MHC Class I Cytoplasmic Transport Pulmonary Artery Morphogenesis Positive Regulation Of Spindle Checkpoint Coronary Artery Morphogenesis Post-translational Protein Modification Growth Hormone Secretion Multicellular Organismal Development Auditory Receptor Cell Stereocilium Organization Anatomical Structure Development Positive Regulation Of Cell Cycle Checkpoint Regulation Of Cell Cycle Coronary Vasculature Morphogenesis Pons Development Lung Lobe Morphogenesis Auditory Receptor Cell Morphogenesis Regulation Of Establishment Of Planar Polarity Involved In Neural Tube Closure Protein Complex Assembly Immune System Process
Tagcloud ?		allow atf6 bbf2h7 canonical cartilage chondrocytes cleaved contrary dual expresses facilitates golgi hedgehog indian luminal neighbouring patched preferentially processed promote resident secreted simultaneously structurally terminus trafficking transducers transmembrane triggered	analyze animal ccnd1 ccni ccni2 cdk16 cdk3 cdk4 cdk8 cdk9 cdkis cdkn1a cdkn2a cdks comprehensive confirm cyclin database diabetic diagram islets microarray pancreatic pattern qrt reproduce snps t2d
Tagcloud (Difference) ?		allow atf6 bbf2h7 canonical cartilage chondrocytes cleaved contrary dual expresses facilitates golgi hedgehog indian luminal neighbouring patched preferentially processed promote resident secreted simultaneously structurally terminus trafficking transducers transmembrane triggered	analyze animal ccnd1 ccni ccni2 cdk16 cdk3 cdk4 cdk8 cdk9 cdkis cdkn1a cdkn2a cdks comprehensive confirm cyclin database diabetic diagram islets microarray pancreatic pattern qrt reproduce snps t2d
Tagcloud (Intersection) ?