SEC23A and SDCBP2

Number of citations of the paper that reports this interaction (PMID 21988832)
14

Data Source:
BioGRID (two hybrid)

		SEC23A	SDCBP2
Gene Name		Sec23 homolog A (S. cerevisiae)	syndecan binding protein (syntenin) 2
Image			No pdb structure
Gene Ontology Annotations	Cellular Component	Golgi Membrane Endoplasmic Reticulum Endoplasmic Reticulum Membrane Cytosol ER To Golgi Transport Vesicle Membrane COPII Vesicle Coat Smooth Endoplasmic Reticulum Membrane Perinuclear Region Of Cytoplasm	Cytoplasm Plasma Membrane Extracellular Vesicular Exosome
	Molecular Function	Protein Binding Zinc Ion Binding	Protein C-terminus Binding Protein Homodimerization Activity Protein Heterodimerization Activity
	Biological Process	Antigen Processing And Presentation Of Peptide Antigen Via MHC Class I Intracellular Protein Transport ER To Golgi Vesicle-mediated Transport Vesicle-mediated Transport Protein N-linked Glycosylation Via Asparagine Antigen Processing And Presentation Of Exogenous Peptide Antigen Via MHC Class II Post-translational Protein Modification Cellular Protein Metabolic Process Small Molecule Metabolic Process COPII Vesicle Coating Membrane Organization	Nervous System Development Intracellular Signal Transduction Intracellular Transport
Pathways		Diseases of glycosylation Metabolism of lipids and lipoproteins Defective ALG14 causes congenital myasthenic syndrome (ALG14-CMS) Transport to the Golgi and subsequent modification Defective MGAT2 causes MGAT2-CDG (CDG-2a) Defective ALG1 causes ALG1-CDG (CDG-1k) Antigen Presentation: Folding, assembly and peptide loading of class I MHC Defective MOGS causes MOGS-CDG (CDG-2b) Regulation of cholesterol biosynthesis by SREBP (SREBF) Defective ALG9 causes ALG9-CDG (CDG-1l) Defective MAN1B1 causes MRT15 MHC class II antigen presentation Class I MHC mediated antigen processing & presentation COPII (Coat Protein 2) Mediated Vesicle Transport ER to Golgi Transport Defective ALG11 causes ALG11-CDG (CDG-1p) Defective ALG2 causes ALG2-CDG (CDG-1i) Defective ALG3 causes ALG3-CDG (CDG-1d) Post-translational protein modification Defective DPAGT1 causes DPAGT1-CDG (CDG-1j) and CMSTA2 Defective B4GALT1 causes B4GALT1-CDG (CDG-2d) Defective ALG6 causes ALG6-CDG (CDG-1c) Defective RFT1 causes RFT1-CDG (CDG-1n) Asparagine N-linked glycosylation Defective ALG8 causes ALG8-CDG (CDG-1h) Defective MPDU1 causes MPDU1-CDG (CDG-1f) Defective ALG12 causes ALG12-CDG (CDG-1g) Diseases associated with N-glycosylation of proteins Adaptive Immune System
Drugs
Diseases
GWAS
Protein-Protein Interactions		9 interactors: CDK16 CDK18 DCTN1 GLRA2 NDRG1 SDCBP2 SEC16A SEC24B SEC24C	41 interactors: ADAP1 ARF4 BEND7 C11orf57 C1orf35 CT45A3 CT45A5 CTH DPPA2 EIF1AD FAM133A FAM13C FAM9B FBXO28 GABRA3 LGALS14 LGALS2 LYAR NFASC NPM2 NRXN1 NUF2 PAFAH1B3 PRPF38A PRPF40A PRR13 PTMS RNPS1 SDCBP SEC23A SREK1IP1 TDO2 THAP6 TIFA TM4SF1 TNP1 YTHDC1 ZCCHC10 ZCCHC17 ZNF581 ZRSR2
Entrez ID		10484	27111
HPRD ID		06714	18032
Ensembl ID		ENSG00000100934	ENSG00000125775
Uniprot IDs		B3KXI2 F5H365 Q15436	Q9H190
PDB IDs		2NUP 2NUT 2YRC 2YRD 3EFO 3EG9 3EGD 3EGX
Enriched GO Terms of Interacting Partners?		COPII Vesicle Coating COPII-coated Vesicle Budding Vesicle Targeting, To, From Or Within Golgi Localization Within Membrane Vesicle Targeting Establishment Of Vesicle Localization Vesicle Localization Membrane Budding Establishment Of Organelle Localization Antigen Processing And Presentation Of Exogenous Peptide Antigen Via MHC Class II Antigen Processing And Presentation Of Peptide Antigen Via MHC Class II ER To Golgi Vesicle-mediated Transport Antigen Processing And Presentation Of Peptide Or Polysaccharide Antigen Via MHC Class II Organelle Localization Establishment Of Localization In Cell Nervous System Development Vesicle Organization Cellular Localization Antigen Processing And Presentation Of Peptide Antigen Vesicle-mediated Transport Golgi Vesicle Transport Intracellular Transport Antigen Processing And Presentation Membrane Organization Neural Nucleus Development Transport Protein N-linked Glycosylation Via Asparagine Protein N-linked Glycosylation Regulation Of Cargo Loading Into COPII-coated Vesicle Cochlear Nucleus Development System Development Antigen Processing And Presentation Of Peptide Antigen Via MHC Class I Cytoplasmic Transport Pulmonary Artery Morphogenesis Positive Regulation Of Spindle Checkpoint Coronary Artery Morphogenesis Post-translational Protein Modification Growth Hormone Secretion Multicellular Organismal Development Auditory Receptor Cell Stereocilium Organization Anatomical Structure Development Positive Regulation Of Cell Cycle Checkpoint Regulation Of Cell Cycle Coronary Vasculature Morphogenesis Pons Development Lung Lobe Morphogenesis Auditory Receptor Cell Morphogenesis Regulation Of Establishment Of Planar Polarity Involved In Neural Tube Closure Protein Complex Assembly Immune System Process	RNA Splicing MRNA Processing MRNA Metabolic Process RNA Processing Cellular Component Assembly Protein Complex Assembly Involved In Synapse Maturation Fertilization, Exchange Of Chromosomal Proteins Gamma-aminobutyric Acid Receptor Clustering Protein Sulfhydration Protein-pyridoxal-5-phosphate Linkage Via Peptidyl-N6-pyridoxal Phosphate-L-lysine Cellular Nitrogen Compound Metabolic Process Locomotion MRNA Splicing, Via Spliceosome RNA Splicing, Via Transesterification Reactions Spliceosomal Complex Assembly Male Pronucleus Assembly Guanylate Kinase-associated Protein Clustering Neuroligin Clustering Protein-pyridoxal-5-phosphate Linkage Transsulfuration Tryptophan Catabolic Process To Acetyl-CoA Gene Expression Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Nitrogen Compound Metabolic Process Gephyrin Clustering Synaptic Vesicle Clustering Hydrogen Sulfide Biosynthetic Process
Tagcloud ?		allow atf6 bbf2h7 canonical cartilage chondrocytes cleaved contrary dual expresses facilitates golgi hedgehog indian luminal neighbouring patched preferentially processed promote resident secreted simultaneously structurally terminus trafficking transducers transmembrane triggered
Tagcloud (Difference) ?		allow atf6 bbf2h7 canonical cartilage chondrocytes cleaved contrary dual expresses facilitates golgi hedgehog indian luminal neighbouring patched preferentially processed promote resident secreted simultaneously structurally terminus trafficking transducers transmembrane triggered
Tagcloud (Intersection) ?