CEACAM5 and CEACAM1

Number of citations of the paper that reports this interaction (PMID 21982860)
4

Data Source:
BioGRID (pull down)

		CEACAM5	CEACAM1
Gene Name		carcinoembryonic antigen-related cell adhesion molecule 5	carcinoembryonic antigen-related cell adhesion molecule 1 (biliary glycoprotein)
Image
Gene Ontology Annotations	Cellular Component	Integral Component Of Plasma Membrane Basolateral Plasma Membrane Anchored Component Of Membrane Extracellular Vesicular Exosome Integral Component Of External Side Of Plasma Membrane	Plasma Membrane Integral Component Of Plasma Membrane Membrane Integral Component Of Membrane Extracellular Vesicular Exosome
	Molecular Function	GPI Anchor Binding Identical Protein Binding Protein Homodimerization Activity	Molecular_function Protein Binding Protein Homodimerization Activity
	Biological Process	Negative Regulation Of Myotube Differentiation Homotypic Cell-cell Adhesion Negative Regulation Of Apoptotic Process Negative Regulation Of Anoikis	Angiogenesis Homophilic Cell Adhesion Via Plasma Membrane Adhesion Molecules Integrin-mediated Signaling Pathway Blood Coagulation Cell Migration Leukocyte Migration
Pathways			Fibronectin matrix formation Cell surface interactions at the vascular wall
Drugs			Arcitumomab Alpha-D-Mannose
Diseases
GWAS
Protein-Protein Interactions		6 interactors: CEACAM1 CEACAM6 EWSR1 HNRNPM PTCHD2 UQCC2	18 interactors: ADRB2 ANXA2 CARTPT CD209 CEACAM3 CEACAM5 CEACAM6 CEACAM7 CEACAM8 EGFR FLNA INSR MAP3K10 PTPN11 PTPN6 PXN SHC1 SRC
Entrez ID		1048	634
HPRD ID		00274	00191
Ensembl ID		ENSG00000105388	ENSG00000079385
Uniprot IDs		P06731 Q68DM9	P13688 Q3KRG8
PDB IDs		1E07 2QSQ 2QST 2VER	2GK2
Enriched GO Terms of Interacting Partners?		Leukocyte Migration Positive Regulation Of Mitochondrial Translation Regulation Of Mitochondrial Translation Regulation Of Oxidative Phosphorylation Mitochondrial Respiratory Chain Complex III Assembly Alternative MRNA Splicing, Via Spliceosome Blood Coagulation Regulation Of Skeletal Muscle Cell Differentiation Hemostasis	Activation Of Protein Kinase Activity Positive Regulation Of Intracellular Signal Transduction Regulation Of MAPK Cascade Positive Regulation Of MAPK Cascade Positive Regulation Of Protein Phosphorylation Positive Regulation Of Protein Kinase Activity Regulation Of Protein Phosphorylation Regulation Of Protein Kinase Activity Regulation Of MAP Kinase Activity Positive Regulation Of Kinase Activity Regulation Of Kinase Activity Positive Regulation Of Transferase Activity Positive Regulation Of Phosphorylation Positive Regulation Of Signal Transduction Positive Regulation Of Protein Modification Process Regulation Of Phosphorylation Positive Regulation Of MAP Kinase Activity Regulation Of Phosphorus Metabolic Process Positive Regulation Of Protein Serine/threonine Kinase Activity Positive Regulation Of Cellular Protein Metabolic Process Regulation Of Protein Metabolic Process Positive Regulation Of Protein Metabolic Process Regulation Of Intracellular Signal Transduction Regulation Of Body Fluid Levels Regulation Of Cellular Protein Metabolic Process Transmembrane Receptor Protein Tyrosine Kinase Signaling Pathway Response To Stress Leukocyte Migration Blood Coagulation Hemostasis Cellular Response To Organonitrogen Compound Peptidyl-tyrosine Phosphorylation Single Organismal Cell-cell Adhesion Regulation Of Catalytic Activity Activation Of MAPK Activity Cellular Response To Peptide Hormone Stimulus Enzyme Linked Receptor Protein Signaling Pathway Cellular Response To Peptide Cellular Response To Hormone Stimulus Epidermal Growth Factor Receptor Signaling Pathway ERBB Signaling Pathway Wound Healing Regulation Of Signal Transduction Positive Regulation Of Catalytic Activity Response To Wounding Positive Regulation Of Transport Response To Peptide Hormone Cell Adhesion Regulation Of Signaling Abortive Mitotic Cell Cycle
Tagcloud ?		adenocarcinoma adenocarcinomas ampulla arising bile bircs bm7 cardia compromising ctc ctcs ducts epcam esophagus great immunomagnetic intestine krt19 muc1 multimarker oncology pancreas pb problematic rectum scgb2a2 stomach vater vu1d9	4l adhesion carcinoembryonic chemotactic clinicopathologic cxcl density explore extent immunohistochemistry infiltration ln lymph metastasis microarray neutrophil neutrophils node overexpression peritumoral poorer probe qrt squamous tissues tongue tscc upregulate upregulating
Tagcloud (Difference) ?		adenocarcinoma adenocarcinomas ampulla arising bile bircs bm7 cardia compromising ctc ctcs ducts epcam esophagus great immunomagnetic intestine krt19 muc1 multimarker oncology pancreas pb problematic rectum scgb2a2 stomach vater vu1d9	4l adhesion carcinoembryonic chemotactic clinicopathologic cxcl density explore extent immunohistochemistry infiltration ln lymph metastasis microarray neutrophil neutrophils node overexpression peritumoral poorer probe qrt squamous tissues tongue tscc upregulate upregulating
Tagcloud (Intersection) ?