CEACAM1 and CEACAM6

Number of citations of the paper that reports this interaction (PMID 8018919)
8

Data Source:
HPRD (in vitro)

		CEACAM1	CEACAM6
Gene Name		carcinoembryonic antigen-related cell adhesion molecule 1 (biliary glycoprotein)	carcinoembryonic antigen-related cell adhesion molecule 6 (non-specific cross reacting antigen)
Image			No pdb structure
Gene Ontology Annotations	Cellular Component	Plasma Membrane Integral Component Of Plasma Membrane Membrane Integral Component Of Membrane Extracellular Vesicular Exosome	Plasma Membrane Integral Component Of Plasma Membrane Anchored Component Of Membrane
	Molecular Function	Molecular_function Protein Binding Protein Homodimerization Activity	Protein Binding
	Biological Process	Angiogenesis Homophilic Cell Adhesion Via Plasma Membrane Adhesion Molecules Integrin-mediated Signaling Pathway Blood Coagulation Cell Migration Leukocyte Migration	Signal Transduction Cell-cell Signaling Blood Coagulation Leukocyte Migration
Pathways		Fibronectin matrix formation Cell surface interactions at the vascular wall	Fibronectin matrix formation Cell surface interactions at the vascular wall
Drugs		Arcitumomab Alpha-D-Mannose
Diseases
GWAS
Protein-Protein Interactions		18 interactors: ADRB2 ANXA2 CARTPT CD209 CEACAM3 CEACAM5 CEACAM6 CEACAM7 CEACAM8 EGFR FLNA INSR MAP3K10 PTPN11 PTPN6 PXN SHC1 SRC	6 interactors: APP CARTPT CEACAM1 CEACAM5 CEACAM7 CEACAM8
Entrez ID		634	4680
HPRD ID		00191	01233
Ensembl ID		ENSG00000079385	ENSG00000086548
Uniprot IDs		P13688 Q3KRG8	P40199
PDB IDs		2GK2
Enriched GO Terms of Interacting Partners?		Activation Of Protein Kinase Activity Positive Regulation Of Intracellular Signal Transduction Regulation Of MAPK Cascade Positive Regulation Of MAPK Cascade Positive Regulation Of Protein Phosphorylation Positive Regulation Of Protein Kinase Activity Regulation Of Protein Phosphorylation Regulation Of Protein Kinase Activity Regulation Of MAP Kinase Activity Positive Regulation Of Kinase Activity Regulation Of Kinase Activity Positive Regulation Of Transferase Activity Positive Regulation Of Phosphorylation Positive Regulation Of Signal Transduction Positive Regulation Of Protein Modification Process Regulation Of Phosphorylation Positive Regulation Of MAP Kinase Activity Regulation Of Phosphorus Metabolic Process Positive Regulation Of Protein Serine/threonine Kinase Activity Positive Regulation Of Cellular Protein Metabolic Process Regulation Of Protein Metabolic Process Positive Regulation Of Protein Metabolic Process Regulation Of Intracellular Signal Transduction Regulation Of Body Fluid Levels Regulation Of Cellular Protein Metabolic Process Transmembrane Receptor Protein Tyrosine Kinase Signaling Pathway Response To Stress Leukocyte Migration Blood Coagulation Hemostasis Cellular Response To Organonitrogen Compound Peptidyl-tyrosine Phosphorylation Single Organismal Cell-cell Adhesion Regulation Of Catalytic Activity Activation Of MAPK Activity Cellular Response To Peptide Hormone Stimulus Enzyme Linked Receptor Protein Signaling Pathway Cellular Response To Peptide Cellular Response To Hormone Stimulus Epidermal Growth Factor Receptor Signaling Pathway ERBB Signaling Pathway Wound Healing Regulation Of Signal Transduction Positive Regulation Of Catalytic Activity Response To Wounding Positive Regulation Of Transport Response To Peptide Hormone Cell Adhesion Regulation Of Signaling Abortive Mitotic Cell Cycle	Blood Coagulation Hemostasis Regulation Of Body Fluid Levels Wound Healing Feeding Behavior Positive Regulation Of Epinephrine Secretion Response To Wounding Negative Regulation Of Cell Differentiation Somatostatin Secretion Synaptic Growth At Neuromuscular Junction Adult Behavior Collateral Sprouting In Absence Of Injury Negative Regulation Of Glucagon Secretion Leukocyte Migration Collateral Sprouting Axon Midline Choice Point Recognition Smooth Endoplasmic Reticulum Calcium Ion Homeostasis Cell Adhesion Axon Choice Point Recognition Locomotion Positive Regulation Of Transmission Of Nerve Impulse Neuron Remodeling Regulation Of Glucagon Secretion Response To Stress Adult Feeding Behavior Negative Regulation Of Appetite Positive Regulation Of Catecholamine Secretion Movement Of Cell Or Subcellular Component Regulation Of Transmission Of Nerve Impulse Negative Regulation Of Bone Resorption Negative Regulation Of Myotube Differentiation Regulation Of Cell Differentiation Negative Regulation Of Bone Remodeling Negative Regulation Of Anoikis Negative Regulation Of Tissue Remodeling Single-organism Behavior Regulation Of Anoikis Cellular Copper Ion Homeostasis Regulation Of Response To Food Negative Regulation Of Striated Muscle Cell Differentiation Secretion By Cell Regulation Of Appetite Copper Ion Homeostasis Suckling Behavior Cellular Chemical Homeostasis Positive Regulation Of G2/M Transition Of Mitotic Cell Cycle Behavior Neuron Maturation MRNA Polyadenylation Regulation Of Epidermal Growth Factor-activated Receptor Activity
Tagcloud ?		4l adhesion carcinoembryonic chemotactic clinicopathologic cxcl density explore extent immunohistochemistry infiltration ln lymph metastasis microarray neutrophil neutrophils node overexpression peritumoral poorer probe qrt squamous tissues tongue tscc upregulate upregulating	adarb2 asymptomatic carriers carrying cntnap2 col19a1 commonest consider def4 dopaminergic draxin fcer2 functionally g2019s hbg1 idiopathic initiating lrrk2 merit ncapg2 never parkinson pd pvrl2 seq slc2a14 snca tcl1b variations
Tagcloud (Difference) ?		4l adhesion carcinoembryonic chemotactic clinicopathologic cxcl density explore extent immunohistochemistry infiltration ln lymph metastasis microarray neutrophil neutrophils node overexpression peritumoral poorer probe qrt squamous tissues tongue tscc upregulate upregulating	adarb2 asymptomatic carriers carrying cntnap2 col19a1 commonest consider def4 dopaminergic draxin fcer2 functionally g2019s hbg1 idiopathic initiating lrrk2 merit ncapg2 never parkinson pd pvrl2 seq slc2a14 snca tcl1b variations
Tagcloud (Intersection) ?