CD2BP2 and CD2

Number of citations of the paper that reports this interaction (PMID 10404223)
15

Data Source:
HPRD (two hybrid, in vitro, in vivo)

		CD2BP2	CD2
Gene Name		CD2 (cytoplasmic tail) binding protein 2	CD2 molecule
Image
Gene Ontology Annotations	Cellular Component	Nucleus Nucleoplasm U5 SnRNP Cytoplasm Nuclear Speck U4/U6 X U5 Tri-snRNP Complex	Extracellular Region Plasma Membrane Integral Component Of Plasma Membrane Cell-cell Junction External Side Of Plasma Membrane Cytoplasmic Side Of Plasma Membrane Cell Surface Anchored Component Of Plasma Membrane
	Molecular Function	Protein Binding Ribonucleoprotein Complex Binding	Receptor Activity Receptor Binding Protein Binding Protein Homodimerization Activity
	Biological Process	Spliceosomal Tri-snRNP Complex Assembly MRNA Splicing, Via Spliceosome RNA Splicing Gene Expression Negative Regulation Of Phosphatase Activity	Membrane Raft Polarization Apoptotic Process Cell Surface Receptor Signaling Pathway Blood Coagulation Single Organismal Cell-cell Adhesion Natural Killer Cell Activation Positive Regulation Of Myeloid Dendritic Cell Activation Positive Regulation Of Tumor Necrosis Factor Production Heterotypic Cell-cell Adhesion T Cell Activation Regulation Of T Cell Differentiation Leukocyte Migration Positive Regulation Of Interferon-gamma Secretion Positive Regulation Of Interleukin-8 Secretion
Pathways		Processing of Capped Intron-Containing Pre-mRNA mRNA Splicing mRNA Splicing - Major Pathway	Cell surface interactions at the vascular wall
Drugs			Alefacept Alpha-D-Mannose
Diseases
GWAS
Protein-Protein Interactions		11 interactors: AKNA CD2 CSNK2A1 PPP1CA PPP1CC PRPF6 PSMF1 SMU1 SNRPB TXNL4A WBP11	19 interactors: CD247 CD2AP CD2BP2 CD4 CD48 CD5 CD53 CD58 CD59 FYN LCK LGALS1 LINC00311 LYAR MXD1 PSTPIP1 PTPRC SH3KBP1 SP1
Entrez ID		10421	914
HPRD ID		05127	01750
Ensembl ID		ENSG00000169217	ENSG00000116824
Uniprot IDs		O95400	P06729 Q53F96
PDB IDs		1GYF 1L2Z 1SYX	1CDB 1GYA 1HNF 1L2Z 1QA9 2J6O 2J7I
Enriched GO Terms of Interacting Partners?		Ribonucleoprotein Complex Biogenesis RNA Splicing MRNA Processing Triglyceride Catabolic Process Entrainment Of Circadian Clock By Photoperiod Ribonucleoprotein Complex Assembly MRNA Metabolic Process Photoperiodism Entrainment Of Circadian Clock Acylglycerol Catabolic Process RNA Processing MRNA Splicing, Via Spliceosome RNA Splicing, Via Transesterification Reactions Gene Expression Cell Cycle Spliceosomal SnRNP Assembly Mitotic Cell Cycle Rhythmic Process Glycogen Metabolic Process Spliceosomal Complex Assembly Negative Regulation Of Proteasomal Protein Catabolic Process Negative Regulation Of Transforming Growth Factor Beta Receptor Signaling Pathway Positive Regulation Of Myeloid Dendritic Cell Activation Negative Regulation Of Cellular Protein Catabolic Process Circadian Regulation Of Gene Expression Polysaccharide Metabolic Process Cell Division Triglyceride Metabolic Process Regulation Of Circadian Rhythm RNA Metabolic Process Regulation Of Transforming Growth Factor Beta Receptor Signaling Pathway Neutral Lipid Metabolic Process Negative Regulation Of Transmembrane Receptor Protein Serine/threonine Kinase Signaling Pathway Negative Regulation Of Cellular Response To Growth Factor Stimulus Negative Regulation Of Protein Catabolic Process Cellular Nitrogen Compound Metabolic Process Membrane Raft Polarization Energy Reserve Metabolic Process Transforming Growth Factor Beta Receptor Signaling Pathway Negative Regulation Of Mitotic Cell Cycle Phase Transition Positive Regulation Of Interferon-gamma Secretion Cellular Lipid Catabolic Process Positive Regulation Of Wnt Signaling Pathway Cellular Macromolecular Complex Assembly Membrane Raft Localization Mitotic Cell Cycle Checkpoint Nitrogen Compound Metabolic Process Circadian Rhythm Mitotic Cell Cycle Process Regulation Of Myeloid Dendritic Cell Activation	Positive Regulation Of T Cell Activation Positive Regulation Of Homotypic Cell-cell Adhesion Positive Regulation Of Cell-cell Adhesion Regulation Of T Cell Activation T Cell Costimulation Positive Regulation Of Cell Activation Regulation Of Cell-cell Adhesion Positive Regulation Of Cell Adhesion Regulation Of Lymphocyte Activation Regulation Of Cell Activation Immune System Process Regulation Of Defense Response To Virus By Virus Regulation Of Cell Adhesion T Cell Receptor Signaling Pathway Antigen Receptor-mediated Signaling Pathway Positive Regulation Of Immune System Process Defense Response Regulation Of Defense Response To Virus Innate Immune Response Cell Migration Locomotion Regulation Of Immune System Process Immune Response-activating Cell Surface Receptor Signaling Pathway Immune Response Cell Motility Signal Transduction Cellular Response To Stimulus Immune Response-regulating Cell Surface Receptor Signaling Pathway Cell Activation Response To Wounding Signaling Lymphocyte Activation Response To Stimulus Cell Communication Blood Coagulation Hemostasis Immune Response-regulating Signaling Pathway Positive Regulation Of Gamma-delta T Cell Differentiation Leukocyte Activation Leukocyte Migration Regulation Of Immune Response Lymphocyte Differentiation Positive Regulation Of Gamma-delta T Cell Activation Single Organismal Cell-cell Adhesion Response To Stress Viral Process T Cell Aggregation T Cell Activation Regulation Of Gamma-delta T Cell Differentiation Lymphocyte Aggregation
Tagcloud ?		24h 48h anova aureus bcap31 caprine challenged chemotactic cxcl6 dairy fosl2 goats granulocyte halves ilt5 infused intramammary intricacy junb lymphotoxin mapk13 mastitis mhcii microarrays mscs pbs udder udders veterinary	2c4 assign b10 b3 b9 complementation crossed crosses crossing facs gbp guanylate hlas hybrids ifn jak1 oas oligoadenylate pairwise permitted responsiveness restore rounds submitted synthetase u3 u4 unresponsive unresponsiveness
Tagcloud (Difference) ?		24h 48h anova aureus bcap31 caprine challenged chemotactic cxcl6 dairy fosl2 goats granulocyte halves ilt5 infused intramammary intricacy junb lymphotoxin mapk13 mastitis mhcii microarrays mscs pbs udder udders veterinary	2c4 assign b10 b3 b9 complementation crossed crosses crossing facs gbp guanylate hlas hybrids ifn jak1 oas oligoadenylate pairwise permitted responsiveness restore rounds submitted synthetase u3 u4 unresponsive unresponsiveness
Tagcloud (Intersection) ?