FLOT1 and INCENP

Number of citations of the paper that reports this interaction (PMID 20430883)
2

Data Source:
BioGRID (pull down)

		FLOT1	INCENP
Gene Name		flotillin 1	inner centromere protein antigens 135/155kDa
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Lysosomal Membrane Endosome Microtubule Organizing Center Caveola Focal Adhesion COP9 Signalosome Membrane Integral Component Of Membrane Flotillin Complex Centriolar Satellite Sarcolemma Melanosome Membrane Raft Extracellular Vesicular Exosome	Chromosome, Centromeric Region Kinetochore Condensed Chromosome Kinetochore Lateral Element Central Element Pericentric Heterochromatin Spindle Cytosol Microtubule Chromocenter Midbody Protein Complex
	Molecular Function	Protease Binding Protein Binding Ionotropic Glutamate Receptor Binding	Protein Binding
	Biological Process	Axonogenesis Extracellular Matrix Disassembly Regulation Of Rho Protein Signal Transduction Establishment Of Protein Localization To Plasma Membrane	Mitotic Cell Cycle Cytokinesis Chromosome Segregation Mitotic Nuclear Division
Pathways			Mitotic Prometaphase Separation of Sister Chromatids Resolution of Sister Chromatid Cohesion Mitotic Anaphase Mitotic Metaphase and Anaphase Cell Cycle, Mitotic M Phase
Drugs
Diseases
GWAS		Ulcerative colitis ( 20848476)	Phospholipid levels (plasma) ( 21829377)
Protein-Protein Interactions		16 interactors: APP ARG1 AURKB CAPN10 CBL FLOT2 FYN GOLM1 INCENP NGB PSMD4 SHBG SORBS1 SORBS2 SORBS3 SRPK1	10 interactors: AURKA AURKB AURKC BIRC5 CBX5 CDCA8 EVI5 FLOT1 H2AFZ HIST2H3C
Entrez ID		10211	3619
HPRD ID		06105	05103
Ensembl ID		ENSG00000137312	ENSG00000149503
Uniprot IDs		B4DVY7 O75955 Q5ST80	Q9NQS7
PDB IDs			2QFA 4AF3
Enriched GO Terms of Interacting Partners?		Cellular Response To Peptide Hormone Stimulus Cellular Response To Peptide Cell Adhesion Response To Peptide Hormone Cellular Response To Organonitrogen Compound Response To Peptide Regulation Of Signaling Positive Regulation Of Cell Cycle Process Organelle Organization Positive Regulation Of Glucose Import Chromosome Segregation Cellular Response To Hormone Stimulus Positive Regulation Of Glucose Transport Actin Cytoskeleton Organization Cytoskeleton Organization Positive Regulation Of Phosphatidylinositol 3-kinase Signaling Actin Filament-based Process Regulation Of L-arginine Import Primary Spermatocyte Growth Positive Regulation Of Cell Cycle Regulation Of Glucose Import Actin Filament Organization Positive Regulation Of Signal Transduction Anaphase-promoting Complex-dependent Proteasomal Ubiquitin-dependent Protein Catabolic Process Regulation Of Epidermal Growth Factor Receptor Signaling Pathway Regulation Of Signal Transduction Regulation Of Phosphatidylinositol 3-kinase Signaling Regulation Of ERBB Signaling Pathway Synaptic Growth At Neuromuscular Junction Type B Pancreatic Cell Apoptotic Process Developmental Cell Growth Response To Organonitrogen Compound Regulation Of Apoptotic Process Feeding Behavior Regulation Of Glucose Transport Histone H3-S28 Phosphorylation Collateral Sprouting In Absence Of Injury Negative Regulation Of Protein Metabolic Process Cytokinesis Negative Regulation Of Apoptotic Process Regulation Of Cell Death Negative Regulation Of Programmed Cell Death Spindle Stabilization Response To Hormone Nucleus Organization Apoptotic Process Collateral Sprouting Axon Midline Choice Point Recognition Negative Regulation Of Cell Death Dendrite Development	Mitotic Spindle Organization Cell Division Histone-serine Phosphorylation Spindle Assembly Mitotic Spindle Assembly Mitotic Nuclear Division Positive Regulation Of Cell Division Spindle Organization Histone Phosphorylation Spindle Stabilization Regulation Of Cytokinesis Positive Regulation Of Cell Cycle Process Chromosome Segregation Regulation Of Cell Division Mitotic Spindle Midzone Assembly Mitotic Spindle Elongation Positive Regulation Of Cell Cycle Mitotic Cell Cycle Process Cell Cycle Mitotic Cell Cycle Spindle Midzone Assembly Attachment Of Spindle Microtubules To Kinetochore Cellular Localization Cytokinesis Peptidyl-serine Phosphorylation Microtubule Cytoskeleton Organization Organelle Assembly Regulation Of Cell Cycle Process Cell Cycle Process Positive Regulation Of Cytokinesis Negative Regulation Of Microtubule Depolymerization Positive Regulation Of Mitotic Nuclear Division Spindle Checkpoint Establishment Of Chromosome Localization Negative Regulation Of Microtubule Polymerization Or Depolymerization Microtubule-based Process Negative Regulation Of Protein Binding Microtubule Anchoring Regulation Of Cell Cycle Anaphase-promoting Complex-dependent Proteasomal Ubiquitin-dependent Protein Catabolic Process Regulation Of Microtubule Polymerization Or Depolymerization Negative Regulation Of Spindle Checkpoint Histone Modification Chromosome Organization Organelle Localization Protein Complex Assembly Protein Localization Negative Regulation Of Protein Complex Disassembly Negative Regulation Of Transcription, DNA-templated Negative Regulation Of Binding
Tagcloud ?		anchorage archived caveolin chicken chorioallantoic constitutive downregulation electrophoretic escc esccs esophageal essc flot2 hyperactivation intermediaries inverse inversely k63 luciferase mir polyubiquitination raft rafts rip1 suppressive traf2 transwell upregulating vital	allele aurkb birc5 cdca8 consortium contribution cpc division european exon familial fifteen fixed genotyped inherited investigates meta modest passenger pivotal rs1675126 rs2071214 snp snps spite sporadic synonymous top variability
Tagcloud (Difference) ?		anchorage archived caveolin chicken chorioallantoic constitutive downregulation electrophoretic escc esccs esophageal essc flot2 hyperactivation intermediaries inverse inversely k63 luciferase mir polyubiquitination raft rafts rip1 suppressive traf2 transwell upregulating vital	allele aurkb birc5 cdca8 consortium contribution cpc division european exon familial fifteen fixed genotyped inherited investigates meta modest passenger pivotal rs1675126 rs2071214 snp snps spite sporadic synonymous top variability
Tagcloud (Intersection) ?