FLOT1 and CAPN10

Number of citations of the paper that reports this interaction (PMID 21988832)
14

Data Source:
BioGRID (two hybrid)

		FLOT1	CAPN10
Gene Name		flotillin 1	calpain 10
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Lysosomal Membrane Endosome Microtubule Organizing Center Caveola Focal Adhesion COP9 Signalosome Membrane Integral Component Of Membrane Flotillin Complex Centriolar Satellite Sarcolemma Melanosome Membrane Raft Extracellular Vesicular Exosome	Cell Mitochondrion Cytosol Plasma Membrane
	Molecular Function	Protease Binding Protein Binding Ionotropic Glutamate Receptor Binding	SNARE Binding Calcium-dependent Cysteine-type Endopeptidase Activity Cytoskeletal Protein Binding
	Biological Process	Axonogenesis Extracellular Matrix Disassembly Regulation Of Rho Protein Signal Transduction Establishment Of Protein Localization To Plasma Membrane	Proteolysis Cellular Component Disassembly Involved In Execution Phase Of Apoptosis Actin Cytoskeleton Reorganization Positive Regulation Of Insulin Secretion Positive Regulation Of Intracellular Transport Cellular Response To Insulin Stimulus Positive Regulation Of Glucose Import Type B Pancreatic Cell Apoptotic Process Positive Regulation Of Type B Pancreatic Cell Apoptotic Process
Pathways
Drugs
Diseases
GWAS		Ulcerative colitis ( 20848476)
Protein-Protein Interactions		16 interactors: APP ARG1 AURKB CAPN10 CBL FLOT2 FYN GOLM1 INCENP NGB PSMD4 SHBG SORBS1 SORBS2 SORBS3 SRPK1	4 interactors: EFNB1 FANCC FLOT1 PSMA7
Entrez ID		10211	11132
HPRD ID		06105	05595
Ensembl ID		ENSG00000137312	ENSG00000142330
Uniprot IDs		B4DVY7 O75955 Q5ST80	Q9HC96
PDB IDs
Enriched GO Terms of Interacting Partners?		Cellular Response To Peptide Hormone Stimulus Cellular Response To Peptide Cell Adhesion Response To Peptide Hormone Cellular Response To Organonitrogen Compound Response To Peptide Regulation Of Signaling Positive Regulation Of Cell Cycle Process Organelle Organization Positive Regulation Of Glucose Import Chromosome Segregation Cellular Response To Hormone Stimulus Positive Regulation Of Glucose Transport Actin Cytoskeleton Organization Cytoskeleton Organization Positive Regulation Of Phosphatidylinositol 3-kinase Signaling Actin Filament-based Process Regulation Of L-arginine Import Primary Spermatocyte Growth Positive Regulation Of Cell Cycle Regulation Of Glucose Import Actin Filament Organization Positive Regulation Of Signal Transduction Anaphase-promoting Complex-dependent Proteasomal Ubiquitin-dependent Protein Catabolic Process Regulation Of Epidermal Growth Factor Receptor Signaling Pathway Regulation Of Signal Transduction Regulation Of Phosphatidylinositol 3-kinase Signaling Regulation Of ERBB Signaling Pathway Synaptic Growth At Neuromuscular Junction Type B Pancreatic Cell Apoptotic Process Developmental Cell Growth Response To Organonitrogen Compound Regulation Of Apoptotic Process Feeding Behavior Regulation Of Glucose Transport Histone H3-S28 Phosphorylation Collateral Sprouting In Absence Of Injury Negative Regulation Of Protein Metabolic Process Cytokinesis Negative Regulation Of Apoptotic Process Regulation Of Cell Death Negative Regulation Of Programmed Cell Death Spindle Stabilization Response To Hormone Nucleus Organization Apoptotic Process Collateral Sprouting Axon Midline Choice Point Recognition Negative Regulation Of Cell Death Dendrite Development
Tagcloud ?		anchorage archived caveolin chicken chorioallantoic constitutive downregulation electrophoretic escc esccs esophageal essc flot2 hyperactivation intermediaries inverse inversely k63 luciferase mir polyubiquitination raft rafts rip1 suppressive traf2 transwell upregulating vital	6c calpain carcinoma cdna clinicopathological clinocopathologcial correction differentially esophageal gaec1 greatest knocking kyse150 microarray microarrays mts normalized oncogene parental prominently psilencer rnai squamous tnrc6c transfected transfecting trinucleotide u133 vector
Tagcloud (Difference) ?		anchorage archived caveolin chicken chorioallantoic constitutive downregulation electrophoretic escc esccs essc flot2 hyperactivation intermediaries inverse inversely k63 luciferase mir polyubiquitination raft rafts rip1 suppressive traf2 transwell upregulating vital	6c calpain carcinoma cdna clinicopathological clinocopathologcial correction differentially gaec1 greatest knocking kyse150 microarray microarrays mts normalized oncogene parental prominently psilencer rnai squamous tnrc6c transfected transfecting trinucleotide u133 vector
Tagcloud (Intersection) ?		esophageal