CDH7 and FGF21

Number of citations of the paper that reports this interaction (PMID 21988832)
14

Data Source:
BioGRID (two hybrid)

		CDH7	FGF21
Gene Name		cadherin 7, type 2	fibroblast growth factor 21
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Plasma Membrane Integral Component Of Membrane	Extracellular Region
	Molecular Function	Calcium Ion Binding	Fibroblast Growth Factor Receptor Binding Protein Binding Growth Factor Activity
	Biological Process	Homophilic Cell Adhesion Via Plasma Membrane Adhesion Molecules Single Organismal Cell-cell Adhesion Cell Junction Assembly Adherens Junction Organization Cell-cell Junction Organization	Signal Transduction Cell-cell Signaling Positive Regulation Of Cell Proliferation Regulation Of Low-density Lipoprotein Particle Clearance Positive Regulation Of Low-density Lipoprotein Particle Receptor Biosynthetic Process Positive Regulation Of Glucose Import Positive Regulation Of ERK1 And ERK2 Cascade Positive Regulation Of MAPKKK Cascade By Fibroblast Growth Factor Receptor Signaling Pathway
Pathways		Cell junction organization Cell-cell junction organization Adherens junctions interactions
Drugs
Diseases
GWAS		Cardiac Troponin-T levels ( 23247143)	Bipolar disorder ( 21926972) Dietary macronutrient intake ( 23372041 23636237) Retinal vascular caliber ( 21060863)
Protein-Protein Interactions		6 interactors: CDH12 CDH15 CDH6 CDH9 CTNNB1 FGF21	5 interactors: CDC25A CDH7 KLB MAPK7 NEDD4
Entrez ID		1005	26291
HPRD ID		12049	09447
Ensembl ID		ENSG00000081138	ENSG00000105550
Uniprot IDs		Q9ULB5	Q9NSA1
PDB IDs
Enriched GO Terms of Interacting Partners?		Adherens Junction Organization Cell Junction Assembly Cell-cell Junction Organization Homophilic Cell Adhesion Via Plasma Membrane Adhesion Molecules Cell-cell Adhesion Via Plasma-membrane Adhesion Molecules Cell-cell Adhesion Cell Adhesion Cellular Component Assembly Positive Regulation Of Muscle Cell Differentiation Schwann Cell Proliferation Negative Regulation Of Mitotic Cell Cycle, Embryonic Cellular Response To Insulin-like Growth Factor Stimulus Positive Regulation Of Epithelial Cell Proliferation Involved In Prostate Gland Development Canonical Wnt Signaling Pathway Involved In Positive Regulation Of Epithelial To Mesenchymal Transition Regulation Of Muscle Cell Differentiation Positive Regulation Of Heparan Sulfate Proteoglycan Biosynthetic Process Canonical Wnt Signaling Pathway Involved In Positive Regulation Of Cardiac Outflow Tract Cell Proliferation Glial Cell Fate Determination Oviduct Development Regulation Of Centriole-centriole Cohesion Renal Inner Medulla Development Renal Outer Medulla Development Mesenchymal Cell Proliferation Involved In Lung Development Positive Regulation Of Determination Of Dorsal Identity Positive Regulation Of Low-density Lipoprotein Particle Receptor Biosynthetic Process Embryonic Skeletal Limb Joint Morphogenesis Canonical Wnt Signaling Pathway Involved In Regulation Of Cell Proliferation Lung Induction Central Nervous System Vasculogenesis Trachea Formation Cellular Response To Indole-3-methanol Regulation Of Centromeric Sister Chromatid Cohesion Renal Vesicle Formation Regulation Of Mitotic Cell Cycle, Embryonic Negative Regulation Of Protein Sumoylation Positive Regulation Of Branching Involved In Lung Morphogenesis Positive Regulation Of MAPKKK Cascade By Fibroblast Growth Factor Receptor Signaling Pathway Regulation Of Low-density Lipoprotein Particle Receptor Biosynthetic Process Regulation Of Secondary Heart Field Cardioblast Proliferation Positive Regulation Of Fibroblast Growth Factor Receptor Signaling Pathway Regulation Of Branching Involved In Lung Morphogenesis Mesenchymal To Epithelial Transition Involved In Metanephros Morphogenesis Fungiform Papilla Formation Canonical Wnt Signaling Pathway Involved In Negative Regulation Of Apoptotic Process Establishment Of Blood-brain Barrier Regulation Of Low-density Lipoprotein Particle Clearance Positive Regulation Of Receptor Biosynthetic Process Muscle Cell Differentiation Fungiform Papilla Morphogenesis Glial Cell Proliferation	Regulation Of Transcription From RNA Polymerase II Promoter In Response To Stress Regulation Of DNA-templated Transcription In Response To Stress Cellular Response To UV Cellular Response To Light Stimulus Negative Regulation Of Transcription From RNA Polymerase II Promoter In Response To UV-induced DNA Damage Transmission Of Virus Development Involved In Symbiotic Interaction Response To UV Cellular Response To Radiation Negative Regulation Of CAMP Catabolic Process Regulation Of Nucleocytoplasmic Transport Negative Regulation Of Cyclic-nucleotide Phosphodiesterase Activity Neurotrophin TRK Receptor Signaling Pathway Neurotrophin Signaling Pathway Progesterone Receptor Signaling Pathway Negative Regulation Of NFAT Protein Import Into Nucleus Regulation Of Transcription From RNA Polymerase II Promoter In Response To UV-induced DNA Damage Immune Response Cellular Response To Laminar Fluid Shear Stress Negative Regulation Of Heterotypic Cell-cell Adhesion Positive Regulation Of MAPKKK Cascade By Fibroblast Growth Factor Receptor Signaling Pathway Glucocorticoid Receptor Signaling Pathway Response To Light Stimulus Regulation Of Phosphorus Metabolic Process Protein Targeting To Lysosome Negative Regulation Of Sodium Ion Transport Negative Regulation Of Vascular Endothelial Growth Factor Receptor Signaling Pathway Negative Regulation Of Transport Protein Localization To Lysosome Positive Regulation Of Transcription From RNA Polymerase II Promoter In Response To Stress Regulation Of Intracellular Transport Response To Radiation Cellular Response To Fluid Shear Stress Response To Laminar Fluid Shear Stress Regulation Of Intracellular Signal Transduction Immune Response-regulating Signaling Pathway Response To Inorganic Substance Negative Regulation Of Oxidative Stress-induced Intrinsic Apoptotic Signaling Pathway Receptor Catabolic Process Cellular Response To Organic Substance Single Organismal Cell-cell Adhesion Protein Targeting To Vacuole CAMP-mediated Signaling Ubiquitin-dependent Protein Catabolic Process Via The Multivesicular Body Sorting Pathway Negative Regulation Of Endothelial Cell Apoptotic Process Regulation Of Oxidative Stress-induced Intrinsic Apoptotic Signaling Pathway Establishment Of Protein Localization To Vacuole Cellular Response To Growth Factor Stimulus Negative Regulation Of Oxidative Stress-induced Cell Death Regulation Of Potassium Ion Transmembrane Transporter Activity
Tagcloud ?			1alpha 3beta akt1 akt2 ampk blots deletion diabetic exacerbates exacerbating examining fatty fibroblast germ gs gsk inactivated ko maintaining pgc protects reflected sirt1 spermatogenesis streptozotocin testes testicular tried
Tagcloud (Difference) ?			1alpha 3beta akt1 akt2 ampk blots deletion diabetic exacerbates exacerbating examining fatty fibroblast germ gs gsk inactivated ko maintaining pgc protects reflected sirt1 spermatogenesis streptozotocin testes testicular tried
Tagcloud (Intersection) ?