FGF21

Gene Name		fibroblast growth factor 21
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Extracellular Region
	Molecular Function	Fibroblast Growth Factor Receptor Binding Protein Binding Growth Factor Activity
	Biological Process	Signal Transduction Cell-cell Signaling Positive Regulation Of Cell Proliferation Regulation Of Low-density Lipoprotein Particle Clearance Positive Regulation Of Low-density Lipoprotein Particle Receptor Biosynthetic Process Positive Regulation Of Glucose Import Positive Regulation Of ERK1 And ERK2 Cascade Positive Regulation Of MAPKKK Cascade By Fibroblast Growth Factor Receptor Signaling Pathway
Pathways
Drugs
Diseases
GWAS		Bipolar disorder ( 21926972) Dietary macronutrient intake ( 23372041 23636237) Retinal vascular caliber ( 21060863)
Protein-protein Interactions		5 interactors: CDC25A CDH7 KLB MAPK7 NEDD4
Entrez ID		26291
HPRD ID		09447
Ensembl ID		ENSG00000105550
Uniprot IDs		Q9NSA1
PDB IDs
Enriched GO Terms of Interacting Partners?		Regulation Of Transcription From RNA Polymerase II Promoter In Response To Stress Regulation Of DNA-templated Transcription In Response To Stress Cellular Response To UV Cellular Response To Light Stimulus Negative Regulation Of Transcription From RNA Polymerase II Promoter In Response To UV-induced DNA Damage Transmission Of Virus Development Involved In Symbiotic Interaction Response To UV Cellular Response To Radiation Negative Regulation Of CAMP Catabolic Process Regulation Of Nucleocytoplasmic Transport Negative Regulation Of Cyclic-nucleotide Phosphodiesterase Activity Neurotrophin TRK Receptor Signaling Pathway Neurotrophin Signaling Pathway Progesterone Receptor Signaling Pathway Negative Regulation Of NFAT Protein Import Into Nucleus Regulation Of Transcription From RNA Polymerase II Promoter In Response To UV-induced DNA Damage Immune Response Cellular Response To Laminar Fluid Shear Stress Negative Regulation Of Heterotypic Cell-cell Adhesion Positive Regulation Of MAPKKK Cascade By Fibroblast Growth Factor Receptor Signaling Pathway Glucocorticoid Receptor Signaling Pathway Response To Light Stimulus Regulation Of Phosphorus Metabolic Process Protein Targeting To Lysosome Negative Regulation Of Sodium Ion Transport Negative Regulation Of Vascular Endothelial Growth Factor Receptor Signaling Pathway Negative Regulation Of Transport Protein Localization To Lysosome Positive Regulation Of Transcription From RNA Polymerase II Promoter In Response To Stress Regulation Of Intracellular Transport Response To Radiation Cellular Response To Fluid Shear Stress Response To Laminar Fluid Shear Stress Regulation Of Intracellular Signal Transduction Immune Response-regulating Signaling Pathway Response To Inorganic Substance Negative Regulation Of Oxidative Stress-induced Intrinsic Apoptotic Signaling Pathway Receptor Catabolic Process Cellular Response To Organic Substance Single Organismal Cell-cell Adhesion Protein Targeting To Vacuole CAMP-mediated Signaling Ubiquitin-dependent Protein Catabolic Process Via The Multivesicular Body Sorting Pathway Negative Regulation Of Endothelial Cell Apoptotic Process Regulation Of Oxidative Stress-induced Intrinsic Apoptotic Signaling Pathway Establishment Of Protein Localization To Vacuole Cellular Response To Growth Factor Stimulus Negative Regulation Of Oxidative Stress-induced Cell Death Regulation Of Potassium Ion Transmembrane Transporter Activity
Tagcloud ?		1alpha 3beta akt1 akt2 ampk blots deletion diabetic exacerbates exacerbating examining fatty fibroblast germ gs gsk inactivated ko maintaining pgc protects reflected sirt1 spermatogenesis streptozotocin testes testicular tried