MAML1

Gene Name		mastermind-like 1 (Drosophila)
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Gene Ontology Annotations	Cellular Component	MAML1-RBP-Jkappa- ICN1 Complex Nucleus Nucleoplasm Nuclear Speck Intracellular Membrane-bounded Organelle
	Molecular Function	Transcription Coactivator Activity Protein Binding Protein Kinase Binding Peptide Antigen Binding
	Biological Process	Atrioventricular Node Development Transcription Initiation From RNA Polymerase II Promoter Protein Phosphorylation Notch Signaling Pathway Positive Regulation Of Transcription Of Notch Receptor Target Gene Expression Positive Regulation Of Myotube Differentiation Myoblast Differentiation Positive Regulation Of Transcription From RNA Polymerase II Promoter Atrioventricular Node Cell Development
Pathways		Signaling by NOTCH1 HD Domain Mutants in Cancer Signaling by NOTCH1 HD+PEST Domain Mutants in Cancer Signaling by NOTCH NOTCH2 intracellular domain regulates transcription Notch-HLH transcription pathway Signaling by NOTCH1 t(7;9)(NOTCH1:M1580_K2555) Translocation Mutant NOTCH1 Intracellular Domain Regulates Transcription Signaling by NOTCH2 Generic Transcription Pathway Pre-NOTCH Transcription and Translation Signaling by NOTCH1 Pre-NOTCH Expression and Processing Signaling by NOTCH1 PEST Domain Mutants in Cancer Signaling by NOTCH1 in Cancer Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants Constitutive Signaling by NOTCH1 PEST Domain Mutants FBXW7 Mutants and NOTCH1 in Cancer
Drugs
Diseases
GWAS
Protein-protein Interactions		10 interactors: CDK8 CREBBP EP300 HDAC9 NOTCH1 NOTCH2 NOTCH3 NOTCH4 PIAS1 RBPJ
Entrez ID		9794
HPRD ID		05665
Ensembl ID		ENSG00000161021
Uniprot IDs		Q92585
PDB IDs		2F8X 3NBN 3V79
Enriched GO Terms of Interacting Partners?		Notch Signaling Pathway Transcription Initiation From RNA Polymerase II Promoter DNA-templated Transcription, Initiation Transcription, DNA-templated Notch Receptor Processing RNA Biosynthetic Process Interleukin-4 Secretion Positive Regulation Of Transcription Of Notch Receptor Target Regulation Of Transcription From RNA Polymerase II Promoter Cell Surface Receptor Signaling Pathway RNA Metabolic Process Interleukin-4 Production Notch Signaling Involved In Heart Development Negative Regulation Of Transcription From RNA Polymerase II Promoter Gene Expression Cellular Macromolecule Biosynthetic Process Macromolecule Biosynthetic Process Cardiovascular System Development Transcription From RNA Polymerase II Promoter Regulation Of Cell Differentiation Regulation Of Transcription, DNA-templated Negative Regulation Of Transcription, DNA-templated Regulation Of Nucleic Acid-templated Transcription Regulation Of RNA Biosynthetic Process Negative Regulation Of Nucleic Acid-templated Transcription Negative Regulation Of RNA Biosynthetic Process Regulation Of RNA Metabolic Process Cell Fate Commitment Nucleobase-containing Compound Metabolic Process Regulation Of Transcription From RNA Polymerase II Promoter In Response To Hypoxia Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Biosynthetic Process Regulation Of Gene Expression Negative Regulation Of Cell Differentiation Regulation Of Nitrogen Compound Metabolic Process Negative Regulation Of Gene Expression Positive Regulation Of Transcription, DNA-templated Immune System Process Defense Response Negative Regulation Of Biosynthetic Process Cellular Nitrogen Compound Metabolic Process Inflammatory Response To Antigenic Stimulus Cytokine Secretion Stem Cell Maintenance Regulation Of Muscle Cell Differentiation Signal Transduction Positive Regulation Of BMP Signaling Pathway Positive Regulation Of Macromolecule Biosynthetic Process N-terminal Peptidyl-lysine Acetylation
Tagcloud ?		adam33 allergen allergens allergic black boston cnot6 cockroach dataset dust fcer1a genotypic haplotype haplotypes house il5ra jak3 marginally mite nod1 rs11739089 rs12136904t rs6665683 rs6665683t rs7851969 sensitization sensitizations snps strongest