PER2

Gene Name		period circadian clock 2
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleus Nucleoplasm Nucleolus Cytoplasm Perinuclear Region Of Cytoplasm
	Molecular Function	Transcription Regulatory Region Sequence-specific DNA Binding Transcription Factor Binding Transcription Factor Activity Core Promoter Binding Transcription Corepressor Binding Transcription Coactivator Activity Signal Transducer Activity Protein Binding Kinase Binding Nuclear Hormone Receptor Binding Pre-mRNA Binding Histone Deacetylase Binding Ubiquitin Binding RNA Polymerase Binding Histone Methyltransferase Binding
	Biological Process	Negative Regulation Of Transcription From RNA Polymerase II Promoter Response To Ischemia Glycogen Biosynthetic Process Gluconeogenesis Transcription, DNA-templated Fatty Acid Metabolic Process Signal Transduction Circadian Rhythm Regulation Of Vasoconstriction Lactate Biosynthetic Process Negative Regulation Of Protein Ubiquitination Circadian Regulation Of Gene Expression Regulation Of Circadian Rhythm Negative Regulation Of Circadian Rhythm Negative Regulation Of Transcription, DNA-templated Regulation Of Neurogenesis Regulation Of Insulin Secretion White Fat Cell Differentiation Regulation Of Cell Cycle Regulation Of Glutamate Uptake Involved In Transmission Of Nerve Impulse Negative Regulation Of DNA-templated Transcription, Termination Negative Regulation Of Fat Cell Proliferation Histone H3 Deacetylation Circadian Regulation Of Translation Negative Regulation Of Transcription Regulatory Region DNA Binding
Pathways		BMAL1:CLOCK,NPAS2 activates circadian gene expression
Drugs
Diseases
GWAS
Protein-protein Interactions		9 interactors: CRY1 CRY2 CSNK1D CSNK1E PER1 PER3 TIMELESS TP53 TPT1
Entrez ID		8864
HPRD ID		04575
Ensembl ID		ENSG00000132326
Uniprot IDs		O15055
PDB IDs
Enriched GO Terms of Interacting Partners?		Regulation Of Circadian Rhythm Circadian Rhythm Rhythmic Process Circadian Regulation Of Gene Expression Entrainment Of Circadian Clock By Photoperiod Photoperiodism Entrainment Of Circadian Clock Negative Regulation Of Glucocorticoid Receptor Signaling Pathway Negative Regulation Of Transcription From RNA Polymerase II Promoter Blue Light Signaling Pathway Negative Regulation Of Intracellular Steroid Hormone Receptor Signaling Pathway Response To Blue Light Negative Regulation Of Signal Transduction Negative Regulation Of Transcription, DNA-templated Negative Regulation Of Nucleic Acid-templated Transcription Negative Regulation Of RNA Biosynthetic Process Regulation Of Intracellular Steroid Hormone Receptor Signaling Pathway Negative Regulation Of Signaling Negative Regulation Of Gene Expression Negative Regulation Of Biosynthetic Process Response To Light Stimulus Cellular Response To Light Stimulus Cellular Response To DNA Damage Stimulus Regulation Of Signal Transduction Protein-chromophore Linkage Response To Radiation Regulation Of Transcription From RNA Polymerase II Promoter Nucleobase-containing Compound Metabolic Process Cellular Response To Radiation Regulation Of Signaling Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Response To Abiotic Stimulus Negative Regulation Of Circadian Rhythm Regulation Of Gene Expression Cellular Nitrogen Compound Metabolic Process Negative Regulation Of Cellular Metabolic Process DNA Repair Transcription, DNA-templated Nitrogen Compound Metabolic Process RNA Biosynthetic Process Response To Stimulus Mitotic Cell Cycle Process Cell Cycle Phase Transition Mitotic Cell Cycle Cellular Response To Stress Cellular Response To Stimulus Response To External Stimulus Positive Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process Positive Regulation Of Proteasomal Protein Catabolic Process
Tagcloud ?		aperiodic arnt brighton brosens chan circadian clock conceptus congruently cryptochrome decidual decidualizing disorganized grossly hescs kaput lacey lucas midluteal miscarriages moore muter oscillations predicated preponderance quenby silences synchronizes uncoupling