POU3F1

Gene Name		POU class 3 homeobox 1
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleus Transcription Factor Complex
	Molecular Function	RNA Polymerase II Transcription Coactivator Activity Sequence-specific DNA Binding Transcription Factor Activity Sequence-specific DNA Binding
	Biological Process	Transcription, DNA-templated Axon Ensheathment Positive Regulation Of Gene Expression Myelination In Peripheral Nervous System Keratinocyte Differentiation Forebrain Development Positive Regulation Of Transcription, DNA-templated Positive Regulation Of Transcription From RNA Polymerase II Promoter
Pathways
Drugs
Diseases
GWAS		Rheumatoid arthritis ( 20453842) Visceral adipose tissue/subcutaneous adipose tissue ratio ( 22589738) Waist-to-hip circumference ratio (interaction) ( 23192594)
Protein-protein Interactions		3 interactors: HMGA1 HMGB2 POU3F4
Entrez ID		5453
HPRD ID		03921
Ensembl ID		ENSG00000185668
Uniprot IDs		Q03052
PDB IDs
Enriched GO Terms of Interacting Partners?		Base-excision Repair DNA Catabolic Process, Endonucleolytic Chromatin Assembly DNA Catabolic Process Nucleosome Organization Chromatin Assembly Or Disassembly Chromatin Remodeling DNA Packaging Oncogene-induced Cell Senescence Senescence-associated Heterochromatin Focus Assembly DNA Conformation Change Positive Regulation Of Cellular Senescence Nucleic Acid Phosphodiester Bond Hydrolysis Base-excision Repair, DNA Ligation Negative Regulation Of Chromatin Silencing Establishment Of Integrated Proviral Latency Positive Regulation Of Cell Aging Aromatic Compound Catabolic Process Establishment Of Viral Latency Positive Regulation Of Megakaryocyte Differentiation DNA Ligation Involved In DNA Repair Heterochromatin Assembly Negative Regulation Of Mesenchymal Cell Apoptotic Process DNA Unwinding Involved In DNA Replication DNA Ligation Nucleosome Disassembly Heterochromatin Organization DNA Repair Chromatin Modification Positive Regulation Of Gene Expression, Epigenetic Regulation Of Megakaryocyte Differentiation Apoptotic DNA Fragmentation Positive Regulation Of Erythrocyte Differentiation Response To Other Organism Chromatin Organization Regulation Of Gene Silencing Response To Biotic Stimulus Regulation Of Cellular Senescence Cochlea Morphogenesis Negative Regulation Of Extrinsic Apoptotic Signaling Pathway Via Death Domain Receptors Positive Chemotaxis Spermatid Nucleus Differentiation V(D)J Recombination Cellular Senescence Cellular Response To DNA Damage Stimulus Apoptotic Nuclear Changes Cellular Macromolecule Catabolic Process Regulation Of Hematopoietic Progenitor Cell Differentiation DNA Topological Change Negative Regulation Of Apoptotic Process
Tagcloud ?		acting additive c38 c40 caat cebpa cebpb collectively commitment composed concert elusive embryonic enhancer epidermis evolutionary fate keratinocyte keratinocytes layer modules p63 p63lre partly pluripotent redundant repress robust