NPHP4

Gene Name		nephronophthisis 4
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Centrosome Cytosol Cell-cell Junction Tight Junction Membrane Photoreceptor Connecting Cilium Ciliary Transition Zone Ribbon Synapse Ciliary Base
	Molecular Function	Structural Molecule Activity Protein Binding
	Biological Process	Organelle Organization Signal Transduction Visual Behavior Single Organismal Cell-cell Adhesion Actin Cytoskeleton Organization Sperm Motility Hippo Signaling Photoreceptor Cell Outer Segment Organization Photoreceptor Cell Maintenance Retina Development In Camera-type Eye Negative Regulation Of Canonical Wnt Signaling Pathway
Pathways		Signaling by Hippo Organelle biogenesis and maintenance Assembly of the primary cilium Anchoring of the basal body to the plasma membrane
Drugs
Diseases
GWAS		QT interval ( 19305408) Response to taxane treatment (placlitaxel) ( 23006423)
Protein-protein Interactions		2 interactors: NPHP1 RPGRIP1
Entrez ID		261734
HPRD ID		06238
Ensembl ID		ENSG00000131697
Uniprot IDs		O75161 Q8IWC0
PDB IDs
Enriched GO Terms of Interacting Partners?		Photoreceptor Cell Development Retina Development In Camera-type Eye Camera-type Eye Development Eye Development Photoreceptor Cell Outer Segment Organization Sensory Organ Development Neuron Development Neuron Differentiation Eye Photoreceptor Cell Development Excretion Eye Photoreceptor Cell Differentiation Generation Of Neurons Neurogenesis Tissue Development Visual Behavior Cell Development Nervous System Development Spermatid Differentiation Eye Morphogenesis Visual Perception Sensory Perception Of Light Stimulus Organ Development Cilium Organization
Tagcloud ?		5e 8e beadchip carbohydrate ckd clu cpg cric determining epigenetically filtration glomerular humanmethylation hypermethylated infinium ingenuity insufficiency iqsec1 islands kidney methylated networks nfkbib nfkbil2 nos3 slope tcf3 tgfb3 tgfbi