AFG3L2

Gene Name		AFG3-like AAA ATPase 2
Image
Gene Ontology Annotations	Cellular Component	Mitochondrion Mitochondrial Inner Membrane Integral Component Of Membrane
	Molecular Function	Metalloendopeptidase Activity Protein Binding ATP Binding Zinc Ion Binding Unfolded Protein Binding
	Biological Process	Proteolysis Axonogenesis Neuromuscular Junction Development Mitochondrial Fusion Death Nerve Development Mitochondrial Protein Processing Regulation Of Multicellular Organism Growth Cristae Formation Myelination Muscle Fiber Development Righting Reflex
Pathways
Drugs		Adenosine triphosphate
Diseases
GWAS
Protein-protein Interactions		4 interactors: APP MAPK8IP2 PHC2 RAC2
Entrez ID		10939
HPRD ID		05205
Ensembl ID		ENSG00000141385
Uniprot IDs		Q8TA92 Q9Y4W6
PDB IDs		2LNA
Enriched GO Terms of Interacting Partners?		Mating Behavior Mating Cell Morphogenesis Involved In Neuron Differentiation Neuron Projection Morphogenesis Cell Morphogenesis Involved In Differentiation Regulation Of Receptor Activity Sexual Reproduction Neuron Projection Development Cell Projection Morphogenesis Cell Part Morphogenesis Learning Dendrite Development Neuron Development Synaptic Growth At Neuromuscular Junction Reproduction Cell Morphogenesis Platelet Activation Neuron Differentiation Cell Projection Organization Collateral Sprouting In Absence Of Injury Reproductive Process Learning Or Memory Collateral Sprouting Axon Midline Choice Point Recognition Nonassociative Learning Cognition Smooth Endoplasmic Reticulum Calcium Ion Homeostasis Axon Choice Point Recognition Generation Of Neurons Neurogenesis Neuron Remodeling Axon Guidance Regulation Of Hydrogen Peroxide Metabolic Process Multicellular Organismal Development Cell Development Blood Coagulation Hemostasis Regulation Of Respiratory Burst Cellular Component Assembly Single-organism Behavior Positive Regulation Of Lamellipodium Assembly Signal Complex Assembly Positive Regulation Of Lamellipodium Organization Axonogenesis Developmental Process Cellular Copper Ion Homeostasis Regulation Of Alpha-amino-3-hydroxy-5-methyl-4-isoxazole Propionate Selective Glutamate Receptor Activity Axon Development Nervous System Development Regulation Of Body Fluid Levels
Tagcloud ?		acetylcysteine anterograde antioxidants ataxia axonal axons consistently cytoskeletal deficiencies deleted depleted dynamin fragmentation gtpase hyperphosphorylation impair inner mitochondrial neurodegeneration neurons observe oma1 opa1 postnatally restored sca28 spinocerebellar transport