RNF10 and COL4A5

Number of citations of the paper that reports this interaction (PubMedID 16169070)
820

Data Source:
HPRD (two hybrid)

		RNF10	COL4A5
Description		ring finger protein 10	collagen type IV alpha 5 chain
Image		No pdb structure
GO Annotations	Cellular Component	Nucleus Cytoplasm	Extracellular Region Collagen Type IV Trimer Extracellular Space Endoplasmic Reticulum Lumen Extracellular Matrix Neuromuscular Junction Collagen-containing Extracellular Matrix
	Molecular Function	Ubiquitin-protein Transferase Activity Protein Binding Transcription Regulatory Region DNA Binding Metal Ion Binding	Extracellular Matrix Structural Constituent Extracellular Matrix Structural Constituent Conferring Tensile Strength
	Biological Process	Negative Regulation Of Schwann Cell Proliferation Positive Regulation Of Myelination Positive Regulation Of Transcription, DNA-templated Positive Regulation Of Transcription By RNA Polymerase II Protein Autoubiquitination	Neuromuscular Junction Development Extracellular Matrix Organization Collagen-activated Tyrosine Kinase Receptor Signaling Pathway
Pathways			Collagen degradation Collagen degradation Extracellular matrix organization Collagen biosynthesis and modifying enzymes Signaling by PDGF Assembly of collagen fibrils and other multimeric structures Integrin cell surface interactions Integrin cell surface interactions Anchoring fibril formation Crosslinking of collagen fibrils Laminin interactions Laminin interactions Non-integrin membrane-ECM interactions ECM proteoglycans NCAM1 interactions Collagen chain trimerization Regulation of expression of SLITs and ROBOs
Drugs
Diseases			Alport syndrome
GWAS		Chronotype ( 26955885) Reticulocyte fraction of red cells ( 27863252) Sensorimotor dexterity ( 31596458) Type 1 diabetes nephropathy ( 23028342)
Interacting Genes		27 interacting genes: CCDC90B COL4A5 EEF1A1 GRB2 KDM1A LRIF1 MDM2 SETDB1 SNCA TERF1 TLE1 TRIM26 UBE2D1 UBE2D2 UBE2D3 UBE2D4 UBE2E1 UBE2E2 UBE2H UBE2I UBE2J2 UBE2O UBE2U UBE2V1 UBE2W UBTD1 UTP14A	19 interacting genes: ANTXR2 ANXA7 APP CD93 CDKN1A DAZAP2 DCN FBLN2 FN1 GLA HABP2 MATN2 MMP9 NR1H2 OSM RNF10 SERPINE2 SMN1 TK1
Entrez ID		9921	1287
HPRD ID		11496	02363
Ensembl ID		ENSG00000022840	ENSG00000188153
Uniprot IDs		A0A024RBP0 Q8N5U6	A7MBN3 P29400 Q49AM6
PDB IDs			5NAZ
Enriched GO Terms of Interacting Partners?
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