COL4A5 and HABP2

Number of citations of the paper that reports this interaction (PubMedID 1724753)
16

Data Source:
HPRD (in vivo)

		COL4A5	HABP2
Description		collagen type IV alpha 5 chain	hyaluronan binding protein 2
Image			No pdb structure
GO Annotations	Cellular Component	Extracellular Region Collagen Type IV Trimer Extracellular Space Endoplasmic Reticulum Lumen Extracellular Matrix Neuromuscular Junction Collagen-containing Extracellular Matrix	Extracellular Region Extracellular Space
	Molecular Function	Extracellular Matrix Structural Constituent Extracellular Matrix Structural Constituent Conferring Tensile Strength	Serine-type Endopeptidase Activity Calcium Ion Binding Glycosaminoglycan Binding Peptidase Activity
	Biological Process	Neuromuscular Junction Development Extracellular Matrix Organization Collagen-activated Tyrosine Kinase Receptor Signaling Pathway	Proteolysis Cell Adhesion
Pathways		Collagen degradation Collagen degradation Extracellular matrix organization Collagen biosynthesis and modifying enzymes Signaling by PDGF Assembly of collagen fibrils and other multimeric structures Integrin cell surface interactions Integrin cell surface interactions Anchoring fibril formation Crosslinking of collagen fibrils Laminin interactions Laminin interactions Non-integrin membrane-ECM interactions ECM proteoglycans NCAM1 interactions Collagen chain trimerization Regulation of expression of SLITs and ROBOs
Drugs			Hyaluronic acid
Diseases		Alport syndrome
GWAS			Blood protein levels ( 29875488) Cardiac troponin-I levels ( 31014085) Central corneal thickness ( 29760442) Eosinophil counts ( 27863252) Eosinophil percentage of white cells ( 27863252) Heel bone mineral density ( 28869591) Ischemic stroke ( 26732560) Peripheral arterial disease (traffic-related air pollution interaction) ( 27082954) Plasma factor VII activating protease levels ( 30070759) Urate levels ( 31578528) Waist-to-hip ratio adjusted for body mass index ( 28430825)
Interacting Genes		19 interacting genes: ANTXR2 ANXA7 APP CD93 CDKN1A DAZAP2 DCN FBLN2 FN1 GLA HABP2 MATN2 MMP9 NR1H2 OSM RNF10 SERPINE2 SMN1 TK1	7 interacting genes: COL4A1 COL4A2 COL4A3 COL4A4 COL4A5 COL4A6 KNG1
Entrez ID		1287	3026
HPRD ID		02363	04890
Ensembl ID		ENSG00000188153	ENSG00000148702
Uniprot IDs		A7MBN3 P29400 Q49AM6	Q14520
PDB IDs		5NAZ
Enriched GO Terms of Interacting Partners?
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