G3BP2 and PHACTR2

		G3BP2	PHACTR2
Description		G3BP stress granule assembly factor 2	phosphatase and actin regulator 2
Image			No pdb structure
GO Annotations	Cellular Component	Cytoplasm Cytosol Cytoplasmic Stress Granule Ribonucleoprotein Complex	Plasma Membrane Platelet Alpha Granule Membrane
	Molecular Function	RNA Binding MRNA Binding Protein Binding Receptor Signaling Complex Scaffold Activity	Actin Binding Protein Phosphatase Inhibitor Activity Protein Binding
	Biological Process	Cytoplasmic Sequestering Of NF-kappaB Ras Protein Signal Transduction Positive Regulation Of Signal Transduction Viral Process Stress Granule Assembly Innate Immune Response MRNA Transport Protein Homooligomerization Positive Regulation Of Stress Granule Assembly	Platelet Degranulation Negative Regulation Of Phosphoprotein Phosphatase Activity
Pathways			Platelet degranulation
Drugs
Diseases
GWAS		Response to (pegylated) interferon in HBeAg-negative hepatitis B ( 30715261) Subjective response to lithium treatment in bipolar disorder ( 26503763) Testicular germ cell tumor ( 28604728)	3-month functional outcome in non-lacunar ischaemic stroke (modified Rankin score) ( 30796134) Erectile dysfunction in type 1 diabetes ( 22704111) Inflammatory bowel disease ( 23128233) Lung Cancer (DNA repair capacity) ( 23108145) Obesity-related traits ( 23251661) Perceived sweetness of sucrose ( 31005972)
Interacting Genes		9 interacting genes: AGO4 CDKL2 MDM2 NFKB1 NFKBIA PHACTR2 PIN1 SDAD1 USO1	1 interacting genes: G3BP2
Entrez ID		9908	9749
HPRD ID		06570	16378
Ensembl ID		ENSG00000138757	ENSG00000112419
Uniprot IDs		A0A024RDB2 A0A024RDE5 Q9UN86	O75167
PDB IDs		5DRV
Enriched GO Terms of Interacting Partners?
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