SEPTIN7 and CDC42EP3

Number of citations of the paper that reports this interaction (PubMedID 11584266)
73

Data Source:
BioGRID (pull down)

		SEPTIN7	CDC42EP3
Description		septin 7	CDC42 effector protein 3
Image			No pdb structure
GO Annotations	Cellular Component	Condensed Chromosome Kinetochore Stress Fiber Nucleus Spindle Cytosol Axoneme Septin Ring Microtubule Cytoskeleton Apical Plasma Membrane Midbody Septin Complex Cell Division Site Cleavage Furrow Extracellular Exosome Sperm Annulus Non-motile Cilium	Cytoplasm Cytosol Cytoskeleton Plasma Membrane Endomembrane System Actin Cytoskeleton
	Molecular Function	GTPase Activity Structural Molecule Activity Protein Binding GTP Binding Identical Protein Binding Cadherin Binding Molecular Adaptor Activity	Protein Binding Cytoskeletal Regulatory Protein Binding GTP-Rho Binding
	Biological Process	Spermatogenesis Regulation Of Embryonic Cell Shape Cell Differentiation Negative Regulation Of Cell Migration Cellular Protein Localization Positive Regulation Of Apoptotic Process Cilium Assembly Cytoskeleton-dependent Cytokinesis Positive Regulation Of Non-motile Cilium Assembly Negative Regulation Of G1/S Transition Of Mitotic Cell Cycle	Signal Transduction Rho Protein Signal Transduction Regulation Of Cell Shape Positive Regulation Of Actin Filament Polymerization Positive Regulation Of Pseudopodium Assembly
Pathways		MAPK6/MAPK4 signaling	MAPK6/MAPK4 signaling
Drugs
Diseases
GWAS			Facial attractiveness (male raters) ( 30946739) Height ( 28552196 20881960 23563607 31562340) Night sleep phenotypes ( 27126917) Rheumatoid arthritis ( 30891314) Total ventricular volume (Alzheimer's disease interaction) ( 21116278)
Interacting Genes		12 interacting genes: ANLN CDC42EP2 CDC42EP3 CDC42EP5 CENPE HDAC6 REL S100A4 SEPTIN10 SEPTIN11 SEPTIN5 SEPTIN9	11 interacting genes: CDC42 DAPK1 LRRK1 LRRK2 MFHAS1 RHOQ SEPTIN6 SEPTIN7 SNCA SRPK1 UMPS
Entrez ID		989	10602
HPRD ID		04398	09364
Ensembl ID		ENSG00000122545	ENSG00000163171
Uniprot IDs		A0A023T695 A0A024RA87 A8K3D0 B4DNE4 G3V1Q4 Q16181	Q9UKI2
PDB IDs		2QAG 3T5D 3TW4 6N0B 6N12
Enriched GO Terms of Interacting Partners?
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