SEPTIN7 and CDC42EP2

Number of citations of the paper that reports this interaction (PubMedID 11584266)
73

Data Source:
BioGRID (pull down)
HPRD (in vitro)

		SEPTIN7	CDC42EP2
Description		septin 7	CDC42 effector protein 2
Image			No pdb structure
GO Annotations	Cellular Component	Condensed Chromosome Kinetochore Stress Fiber Nucleus Spindle Cytosol Axoneme Septin Ring Microtubule Cytoskeleton Apical Plasma Membrane Midbody Septin Complex Cell Division Site Cleavage Furrow Extracellular Exosome Sperm Annulus Non-motile Cilium	Cytoplasm Cytosol Cytoskeleton Plasma Membrane Endomembrane System Microtubule Cytoskeleton Membrane Phagocytic Vesicle
	Molecular Function	GTPase Activity Structural Molecule Activity Protein Binding GTP Binding Identical Protein Binding Cadherin Binding Molecular Adaptor Activity	Opioid Peptide Activity GTPase Activator Activity Protein Binding GTP-Rho Binding
	Biological Process	Spermatogenesis Regulation Of Embryonic Cell Shape Cell Differentiation Negative Regulation Of Cell Migration Cellular Protein Localization Positive Regulation Of Apoptotic Process Cilium Assembly Cytoskeleton-dependent Cytokinesis Positive Regulation Of Non-motile Cilium Assembly Negative Regulation Of G1/S Transition Of Mitotic Cell Cycle	Actin Filament Organization Rho Protein Signal Transduction Regulation Of Cell Shape Actin Cytoskeleton Organization Positive Regulation Of Actin Filament Polymerization Positive Regulation Of Pseudopodium Assembly Positive Regulation Of Protein Complex Assembly Positive Regulation Of GTPase Activity Cellular Response To Interferon-gamma
Pathways		MAPK6/MAPK4 signaling	MAPK6/MAPK4 signaling
Drugs
Diseases
GWAS			Acne (severe) ( 24927181) Mean corpuscular volume ( 27863252)
Interacting Genes		12 interacting genes: ANLN CDC42EP2 CDC42EP3 CDC42EP5 CENPE HDAC6 REL S100A4 SEPTIN10 SEPTIN11 SEPTIN5 SEPTIN9	7 interacting genes: ARHGAP26 CDC42 NME7 RHOQ SEPTIN6 SEPTIN7 SNCA
Entrez ID		989	10435
HPRD ID		04398	09363
Ensembl ID		ENSG00000122545	ENSG00000149798
Uniprot IDs		A0A023T695 A0A024RA87 A8K3D0 B4DNE4 G3V1Q4 Q16181	O14613
PDB IDs		2QAG 3T5D 3TW4 6N0B 6N12
Enriched GO Terms of Interacting Partners?
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